We are delighted to welcome Dr. Uma Ramakrishnan for this thematic discussion on how genetics can be brought to bear more effectively on specific aspects of snow leopard conservation. Dr. Uma Ramakrishnan starts by exploring the reasons species go extinct, and describes how genetic methods and data can inform our understanding of species’ futures. Uma gives some examples of her work with tigers, and summarise their knowledge on snow leopard conservation genetics, including work to estimate snow leopard population size. Finally, she describes ongoing efforts (in collaboration with scientists at Stanford University) to understand more about snow leopards globally and locally. Dr. Byron Weckworth, Director of Panthera’s Snow Leopard and Conservation Genetic programs, joins us as principal discussant.