Abstract: A high percentage of rare species in Central Asia experience limited conditions for distribution. Geographic centers with higher species diversity are generally constrained in terms of territory: they are formed when ranges overlap. But in Central Asia and along its borders with Russia, centers of biodiversity overlap at the very marginal edges of ranges. Central Asian species cross into Russian territory, where desert and steppe are replaced by thick forest. Here the northern borders of their ranges are sharply fragmented and isolated. Typical examples for Central Asia are the ranges of the cheetah (Acinonyx jubatus), Asian leopard (Panthera pardus caucasica), striped hyena (Hyaena hyaena), Bukhara deer (Census elaphus bactrianus), markhor (Capra falconeri), blue sheep (Pseudois nayauf) and argali (Ovis ammon). In Russia are the Altai subspecies of argali, the Siberian argali (O.a.ammon), the mountain goat (Capra sibirica), Mongolian gazelle (Procapra gutturosa), snow leopard (Uncia uncia), Pallas' cat (Felis manul), dhole (Cuon alpinus), grey marmot (Marmota baibacina), Mongolian marmot (M. sibirica) and tolai hare (Lepus tolai). Where the numbers o f individuals has fallen to extreme lows, the most effective mechanism for species survival may be supporting the integrity of ranges, in order to preserve population exchanges between neighboring groups. The geographic location of reserves and other protected territories is vitally important for the survival of Central Asian species, given the acute fragmentation of their ranges. These reserves should include significant, viable centers of population the key places. Wherever the creation of permanent protected territories is impossible, a new tactic must be found, such as introducing temporary limitations on the use of land for agriculture and hunting. But all protected territories, whether temporary or permanent, should be connected, forming a core and periphery. The marginal range areas must not be forgotten, if total protection of endangered populations is to be accomplished.