Abstract: There is adducing information about number and modern condition of C.ferox, G.barbatus, A.chrisa‰tus, M.menzbieri, U.arctosisabellinus, L.lutra seistanica, H.hiena, F.lynx isabellina, U.uncia, C.elaphus bactrianus, G.subgutturoza, C.falconeri, O. ammon severtzovi, O. orientalis bochariensis and other species during last years in Chatkal, Nuratau, Hissar, Surkhan and Kyzylkum nature reserves. There is prognosis in changing of number.