Jalanka, H. H., & Roeken, B. (1990). The use of Medetomidine, Medetomidine-Ketamine combinations, and Atipamezole in nondomestic mammals: A review. Journal-of-Zoo-and-Wildlife-Medicine, 21(3), 259–282.
Abstract: The recent development of potent and specifica lphar-adrenoceptoar gonistsa nd antagonists has enhanced their use in nondomestic animal immobilization and reversal. Medetomidine, a new potent alphar-agonist, in combination with the dissociative anesthetic ketamine, has been used to immobilize a variety of nondomestic mammals. Medetomidine alone induces sedation in a dose-dependent way, and complete immobilization has been achieved with high doses in semidomesticated reindeer (Rangifer tarandus) and blue foxes (Alopex lagopus). Howbver, we feel that ketamine should be added to the immobilization mixture to ensure complete immobilization and operator safety. In ketamine combinations, medetomidine doses are usually 60-100 pg/kg. The required ketamine doses are remarkably low:0.8-1.6 mglkg in most ruminants,2.5-3.0 mgUgin felids,u rsids,a nd canids,a nd 5.G-8.0m glkgi n primates,w olverines(Gulog ulo),ando therm uitelids. Clinically, the resulting immobilization is characterized by a smooth onset, good to excellent myorelaxation, and areflexia at higher doses. Determinations of hematologic, serum biochemicil, arterial blood gas,a nd acid-bases tatusp arametersi ndicate that the immobilization is physiologically sound. We have had no fatalities attributable to the immobilization mixture ( I ,240 immobilizations). The alphar-adrenoceptora ntagonist,a tipamezole,i s highly efective in reversingt he immobilization induced by medetomidine, medetomidine-ketamine combinations, or xylazine. In ruminants, the medetomidine-ketamine-induced immobilization can be rapidly and persistently reversed by administering 100-l 50 1rg/kg of alipamezole i.v. and the rest s.c., adjusting the total atipamezole dose to an atipamezole: medetomidine ratio of approximately 4-5 (w/w). Becauseth e required ketamine doses are relatively high in carnivores, we prefer to use a lower atipamezole dose (totil atipamezoie: medetomidine ratio approximately 2-3 w/w) and to administer it i.m. or s.c. Using thii regimen, reversals are calm and animals show minimal “residual ketamine effect.” Because atipamezole is a competitive antagonist, its dose should be reduced if it is administered late in the immobilization period when a large part of medetomidine has been endogenously metabolized. Xylazine-induced immobilization is rapidly reversed by I mg of atipamezole for every 8-12 mg of xylazine used.
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De Groot, H., Van Swieten, P., & Aalberse, R. C. (1990). Evidence for a Fel d I-like molecule in the “big cats” (Felidae species). J Allergy Clin Immunol, 86(1), 107–116.
Abstract: In this study, we investigated the cross-reactivity pattern of IgE and IgG4 antibodies to the major feline allergen, Fel d I. We studied the IgE and IgG4 response of 11 cat-allergic patients against Fel d I-like structures in eight members of the Felidae family: ocelot, puma, serval, siberian tiger, lion, jaguar, snow leopard, and caracal. Hair from these “big cats” was collected, extracted, and used in a RAST system and histamine-release test. By means of a RAST-inhibition assay with affinity-purified Fel d I from cat dander, it was established that, in the Felidae species, a Fel d I equivalent is present that reacts with IgE and IgG4 antibodies. We found that all patients had cross-reacting IgE antibodies to seven of the Felidae tested; no IgE antibodies reactive with the caracal were found. Eight of 10 patients with IgG4 antibodies directed to cat dander also had IgG4 antibodies directed to several Felidae species, including the caracal. However, the correlation between the IgE and the IgG4 antibody specificity was low, indicating that, in the case of Fel d I IgE and IgG4, antibodies do not necessarily have the same specificity.
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Fox, J. L., & Nurbu, C. (1990). Hemis, a national park for snow leopards in India's Trans-Himalaya. Int.Pedigree Book of Snow Leopards, 6, 71–84.
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Fox, J. L., Sinha, S.P., Chundawat, R.S. (1992). Activity patterns and habitat use of ibex in the Himalaya mountains of India. Journal of Mammology, 73(3), 527–534.
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Meiers, S. T. (1992). Habitat use by captive puma (Felis concolor) and snow leopards (Pathera uncia) at the Lincoln Park Zoo, Chicago, Illinois. Ph.D. thesis, DePaul University, .
Abstract: Between May 1990 and January 1991, behavioral observations were made of two captive pumas (Felis concolor Linnaeus), and two captive snow leopards (Panthera uncia Schreber) in their outdoor exhibits at the Lincoln Park Zoological Gardens, Chicago, Illinois. Behaviors compared within and between species included: 1) time spend in the different habitat types; 2) time budgets for the different behaviors: laying, moving, sitting, standing, crouching, in the tree, drinking, urinating, defecating, within their inside dens, and “behavior not determined” when the identity or behavior of the individuals could not be determined; and 3) mobility of the animals within their exhibits. Also examined were: 4) preferences for different habitat types; 5) recommendations for future exhibit designs. Both species located themselves within their exhibits in a non-random manner. The majority of cats' time was spent in elevated locations (i.e., gunite ledges approximately 1-5.5 m above ground-level). Snow leopards exhibited this tendency to a greater extent than did the pumas. Both species also spent the majority of their time in the lying-down behavior; again snow leopards displayed this tendency significantly more than the pumas. Pumas were highly mobile and changed locations and behaviors in their exhibit significantly more than the snow leopards. No significant differences were noted between conspecifics in regard to habitat type preference, or mobility within the exhibit. Suggestions for future exhibit design include elevated locations for the cats to lay and look around within and outside their exhibits, caves for access to shade or relief from inclement weather, and ground surfaces to move about on. Features for exhibit design should take into consideration the natural habitat of the cat to occupy the exhibit.
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Miller, D. J., & Jackson, R. (1994). Livestock and Snow Leopards:making room for competing users on the Tibetian Plateau. In J.L.Fox, & D.Jizeng (Eds.), (pp. 315–328). Usa: Islt.
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Fox, J., Nurbu, C., Bhatt, S., & Chandola, A. (1994). Wildlife conservation and land-use changes in the Transhimalayan region of Ladakh, India (Vol. 14).
Abstract: Changes in economy and land use are under way in the Indian Transhimalayan region of Ladakh, creating both negative and positive prospects for wildlife conservation in this sparsely populations and previously remote area. New livestock breeds, irrigation developments, farming practices, foreign tourists, and a large military presence are changing the way people view and use the mountainous land that surrounds them. With only 0.3% of the land currently arable, changes in wildlife and natural resource conservation are most apparent on Ladakh's extensive rangelands which are apparently undergoing a redistribution of use associated with social changes and recently introduced animal husbandry and farming practices. International endangered species such as the snow leopard, several wild ungulates, and the black-necked crane provide special incentive for conservation efforts in what are some of the best remaining natural areas in the mountainous regions to the north of the Himalayan crest. The success of newly created protected areas for wildlife conservation in Ladakh rests on an understanding of the effects of various development directions, a commitment to environmentally sensitive development amid the many competing demands on Ladakh's natural resources, conservation laws appropriate to human needs, and a clear recognition that solutions can be neither directly adaptable from other mountainous areas nor even widely applicable across the Himalayan region.
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Jafri, R. H., & Shah, F. (1994). The role of education and research in the conservation of snow leopard and its habitat in Northern Pakistan. In J.L.Fox, & D.Jizeng (Eds.), (pp. 273–277). Usa: Islt.
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Lutz, H., Isenbugel, E., & Lehmann, R. (1994). Retrovirus serology in snow leopards and other wild felids in European zoos. In J.L.Fox, & D.Jizeng (Eds.), (pp. 203–208). Usa: Islt.
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McCarthy, T. (2000). Ecology and Conservation of Snow Leopards, Gobi Brown Bears, and Wild Bactrian Camels in Mongolia. Ph.D. thesis, University of Massachusetts, Amherst, .
Abstract: Snow leopard ecology, distribution and abundance in Mongolia were studied between 1993 and 1999. I placed VHF and satellite radio-collars on 4 snow leopards, 2 males and 2 females, to determine home ranges, habitat use, movements, and activity. Home ranges of snow leopards in Mongolia were substantially larger than reported elsewhere. Males ranged over 61 – 142 km2 and female 58 to 1,590 km2. Cats had crepuscular activity patterns with daily movements averaging 5.1 km. Intraspecific distances averaged 1.3 km for males to 7.8 km for males. Leopards selected moderately to very-broken habitat with slopes > 20o, in areas containing ibex. Leopard distribution and abundance was determined using sign surveys. Leopard range in Mongolia is approximately 103,000 km2 but cats are not uniformly distributed within that range. High-density areas include the eastern and central Transaltai Gobi and the northern Altai ranges. Relative leopard densities compared well with relative ibex densities on a regional basis. A snow leopard conservation plan was drafted for Mongolia that identifies problems and threats, and provides an action plan. Wild Bactrian camels occur in the Great Gobi National Park (GGNP) and are thought to be declining due to low recruitment. I surveyed camels by jeep and at oases, observing 142 (4.2% young) and 183 (5.3% young) in 1997 and 1998. Current range was estimated at 33,300 km2. Some winter and calving ranges were recently abandoned. Track sizes and tooth ages from skulls were used to assess demographics. A deterministic model was produced that predicts camel extinction within 25 to 50 years under current recruitment rates and population estimates. Gobi brown bears are endemic to Mongolia and may number less than 35. Three population isolates may occur. I collected genetic material from bears at oases using hair traps. Microsatellite analyses of nuclear DNA determined sixteen unique genotypes, only two of which occurred at more than one oases. Genetic diversity was very low with expected heterozygosity = 0.32, and alleles per locus = 2.3. Mitochondrial DNA sequences were compared to other clades of brown bear and found to fall outside of all known lineages.
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