||There are two isolated snow leopard populations in Uzbekistan, both of which are located along the fringe of the species' distribution. These groups are the Pamir-Alai and the Tien-Shan, of which are united to snow leopard range in neighboring Tadjikistan and Kyrgyzstan. Apart from animals inhabiting the Hissar Nature Reserve, the Pamir-Alai population consists of animals inhabiting the upper portion of the Tupalang River basin and the mountains around Baisuntau. This population is currently estimated at about 30 individuals, from which as many as 10 individuals are reported to be killed or captured annually. However, we suspect the loss rate is more like five to eight individuals, with the entire Pamir-Alai group in Uzbekistan numbering 22 – 25 animals. The Tien-Shan snow leopard sub-population group of Uzbekistan occupies the high-mountain portions of practically all of the large ridges in the area, including Chatkal, Pskem, Ugam and Talass Alatau. The number of snow leopards harvested from this sub-population appears to be five or seven individuals, with the total number placed at 27-32 individuals. The major factors restricting snow leopard numbers in Uzbekistan appears to be poaching of both snow leopard and its large prey species like ibex, as well as disturbance associated with the intensive development of the alpine lands for pasturing livestock. In order to preserve the snow leopard in Uzbekistan it will be necessary to control and eliminate poaching. Additional habitat could be provided by expanding the Chatkal Nature Reserve by adding lands in the Shavassai River basin as well as Akbulak River basin.