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Author Wahlberg, C.; Tarkkanen, A.
Title On the multiple ocular coloboma with retinal dysplasia (MOC) in snow leopards, Pantera uncia Type Book Chapter
Year (up) 1980 Publication International Pedigree Book of Snow Leopards Abbreviated Journal
Volume 2 Issue Pages 183-194
Keywords multiple; Coloboma; retinal; Retinal-Dysplasia; dysplasia; snow; snow leopards; snow leopard; snow-leopards; snow-leopard; leopards; leopard; uncia; International; pedigree
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Publisher Helsinki Zoo Place of Publication Helsinki Editor Blomqvist, L.
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Notes Approved no
Call Number SLN @ rana @ 1096 Serial 999
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Author Phillips, L.G.
Title Palpebral coloboma in three snow leopards Type Report
Year (up) 1981 Publication Abbreviated Journal
Volume Issue Pages 1-8
Keywords snow leopard, captive, Henry Doorly Zoo, Omaha, Palpebral coloboma
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Language English Summary Language Original Title
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Notes Approved no
Call Number SLN @ rana @ Serial 1193
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Author Wahlberg, C.; Tarkkanen, A.; Blomqvist, L.
Title Further observations on the multiple ocular coloboma (MOC) in the snow leopard, Panthers uncia Type Book Chapter
Year (up) 1982 Publication International Pedigree Book of Snow Leopards Abbreviated Journal
Volume 3 Issue Pages 139-144
Keywords observations; multiple; Coloboma; snow; snow leopard; snow-leopard; leopard; uncia; International; pedigree; snow leopards; snow-leopards; leopards; Syndrome; eye; colobomatous; retinal; Retinal-Dysplasia; dysplasia; Case; zoo; factor
Abstract The first observation of the occurrence of multiple ocular coloboma (MOC) in a snow leopard was reported in the International Pedigree Book of Snow Leopards Volume I in 1978 (1). The lesions in this syndrome consist of coloboma of the upper eye lid and uveal coloboma of the globe. Even colobomatous retinal cysts and retinal dysplasia have been noted. The ethiology of in all ten cases of MOC in the snow leopards kept at the Helsinki Zoo were described and discussed in detail in Volume II of the International Pedigree Book of Snow Leopards (2,3). Three cases of MOC in the snow leopards kept at Henry Doorly Zoo, Omaha, Ne., have been described by Phillips (4), one case is known of in Amsterdam (van Bree, personal communication), and two cases in Zoo Zurich (Isenbugel and Weilenmann, pers. comm.) The ethiology of the defect is still not known although various theories ranging from genetic to exogenous factors have been presented.
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Publisher Helsinki Zoo Place of Publication Helsinki Editor Blomqvist, L.
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Notes Approved no
Call Number SLN @ rana @ 982 Serial 1000
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Author Schaffer, E.; Wiesner, H.; Von Hegel, G.
Title Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) Type Journal Article
Year (up) 1988 Publication Tierarztl Prax Abbreviated Journal
Volume 16 Issue 1 Pages 87-91
Keywords Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german
Abstract In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin.
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ISSN 0303-6286 ISBN Medium
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Notes Document Type: German Approved no
Call Number SLN @ rana @ 112 Serial 851
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Author Martin, C.L.; Stiles, J.; Willis, M.
Title Feline colobomatous syndrome Type Journal Article
Year (up) 1997 Publication Veterinary-and-Comparative-Ophthalmology Abbreviated Journal
Volume 7 Issue 1 Pages 39-43
Keywords Blindness; Colobomatous-Syndrome; Congenital-Disease; Eye-Disease; Eyelid-Agenesis; Microphthalmos; Nervous-System; Nervous-System-Disease; Optic-Nerve; Retinal-Dysplasia; Sense-Organs; Veterinary-Medicine; veterinary; medical; browse; colobomatous; Syndrome; congenital; Disease; eye; eyelid; agenesis; nervous; system; Optic; Nerve; retinal; dysplasia; sense; organs; medicine; 1330
Abstract A syndrome of multiple congenital ocular anomalies in a litter of domestic kittens is described which appears identical to the multiple colobomatous syndrome described in captive Snow Leopards. The lesions varied between kittens in the litter, but ranged from microphthalmos with blindness to mild alterations in the lateral lid margins that resulted in trichiasis. The syndrome of eyelid agenesis in the domestic cat may encompass a broad range of congenital ocular lesions and multiple siblings, but the cause and mechanism of lesion formation is unknown.
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Notes Document Type: English Approved no
Call Number SLN @ rana @ 319 Serial 650
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Author Barnett, K.C.; Lewis, J.C.M.
Title Multiple ocular colobomas in the snow leopard (Uncia uncia) Type Miscellaneous
Year (up) 2002 Publication Veterinary Ophthalmology Abbreviated Journal
Volume 5 Issue Pages 197-199
Keywords captive; Coloboma; cub; eyelid; ocular fundus; snow leopard; Uncia uncia
Abstract Two singleton female snow leopard cubs are reported with bilateral central upper lid colobomas. In addition, one cub had a coloboma of the fundus in one eye extending from the lower optic disc region. Surgical treatment by wedge resection was successful in both cases. Details of ocular colobomas in the other snow leopards reported in the literature are described and it is suggested that the exact etiology of the condition in this species may be discovered by further study of similar colobomas in the domestic cat.
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Notes Approved no
Call Number SLN @ rana @ 913 Serial 119
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