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Author De Groot, H.; Van Swieten, P.; Aalberse, R.C.
Title Evidence for a Fel d I-like molecule in the “big cats” (Felidae species) Type Journal Article
Year (up) 1990 Publication J Allergy Clin Immunol Abbreviated Journal
Volume 86 Issue 1 Pages 107-116
Keywords Adolescence; Adult; Allergens; immunology; Animal; Antibodies; Monoclonal; diagnostic; use; Antibody; Specificity; Carnivora; Cats; Comparative; study; Cross; Reactions; Hair; Histamine; Release; Human; IgE; analysis; IgG; Middle; Age; Radioallergosorbent; Test; methods; Support; Non-U.S.Gov't; browse; us; government; gov't; 240
Abstract In this study, we investigated the cross-reactivity pattern of IgE and IgG4 antibodies to the major feline allergen, Fel d I. We studied the IgE and IgG4 response of 11 cat-allergic patients against Fel d I-like structures in eight members of the Felidae family: ocelot, puma, serval, siberian tiger, lion, jaguar, snow leopard, and caracal. Hair from these “big cats” was collected, extracted, and used in a RAST system and histamine-release test. By means of a RAST-inhibition assay with affinity-purified Fel d I from cat dander, it was established that, in the Felidae species, a Fel d I equivalent is present that reacts with IgE and IgG4 antibodies. We found that all patients had cross-reacting IgE antibodies to seven of the Felidae tested; no IgE antibodies reactive with the caracal were found. Eight of 10 patients with IgG4 antibodies directed to cat dander also had IgG4 antibodies directed to several Felidae species, including the caracal. However, the correlation between the IgE and the IgG4 antibody specificity was low, indicating that, in the case of Fel d I IgE and IgG4, antibodies do not necessarily have the same specificity.
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ISSN 0091-6749 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 157 Serial 233
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Author Chundawat, R.S.
Title Studies on Snow Leopard and Prey Species in Hemis National Park Type Miscellaneous
Year (up) 1993 Publication Abbreviated Journal
Volume xi Issue Pages
Keywords Himalayas; India; protected-areas-network; flagship-species; Ladkh; Jammu; Kashmir; transects; field-study; research; scat; browse; 4670
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Publisher Islt Place of Publication Seattle Editor
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Notes Full Text at URLJournal Title: Snow Line Approved no
Call Number SLN @ rana @ 454 Serial 225
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Author Hochstrasser, K.; Wachter, E.; Reisinger, P.W.; Greim, M.; Albrecht, G.J.; Gebhard, W.
Title Amino acid sequences of mammalian kazal-type proteinase inhibitors from salivary glands Type Journal Article
Year (up) 1993 Publication Comp Biochem Physiol B Abbreviated Journal
Volume 106 Issue 1 Pages 103-108
Keywords Amino; Acid; Sequence; Animal; Carnivora; Comparative; study; Cysteine; chemistry; Glycosylation; Mink; Molecular; Data; Protease; Inhibitors; Salivary; Proteins; species; Specificity; Submandibular; Gland; Trypsin; Inhibitor; Kazal; Pancreatic; browse; 200
Abstract 1. The amino acid sequences of bikazins (the double-headed Kazal-type proteinase inhibitors from submandibular glands) isolated from the snow leopard (Unica unica), the European mink (Mustela lutreola), and the European pine marten (Martes martes) were determined. 2. N-terminal domains of bikazins are characterized by a cysteine residue spacing that differs from that of C-terminal domains of bikazins and other Kazal-type proteinase inhibitor domains. 3. N-terminal sequences of bikazins seem to be specific for, and highly conserved within, each Carnivora family.
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ISSN 0305-0491 ISBN Medium
Area Expedition Conference
Notes Document Type: eng Approved no
Call Number SLN @ rana @ 202 Serial 385
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Author Jackson, R.; Zongyi, W.; Xuedong, L.; Yun, C.
Title Snow Leopards in the Qomolangma Nature Preserve of Tibet Autonomous Region Type Conference Article
Year (up) 1994 Publication Abbreviated Journal
Volume Issue Pages 85-95
Keywords Qomolangma; protected-area; parks; preserves; refuge; Nepal; Tibet; China; field-study; blue-sheep; scrapes; sprays; scat; feces; pug-marks; sign; transects; interviews; herders; livestock; predation; predator; traps; trapping; habitat; status; distribution; threats; hunting; pelts; skins; fur; coats; poaching; bones; medicine; Cites; conflict; trade; conservation; management; protected area; protected; area; areas; protected areas; field study; field; study; pug marks; blue; sheep; browse; pug; marks; 3490
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Publisher Islt Place of Publication Usa Editor J.L.Fox; D.Jizeng
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Notes Full Text at URLTitle, Monographic: Seventh International Snow Leopard SymposiumPlace of Meeting: ChinaDate of Copyright: 1994 Approved no
Call Number SLN @ rana @ 231 Serial 452
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Author Roth, T.L.; Howard, J.G.; Donoghue, A.M.; Swanson, W.F.; Wildt, D.E.
Title Function and culture requirements of snow leopard (Panthera uncia) spermatozoa in vitro Type Journal Article
Year (up) 1994 Publication J Reprod Fertil Abbreviated Journal
Volume 101 Issue 3 Pages 563-569
Keywords Animal; Carnivora; physiology; Cell; survival; Cells; Cultured; Comparative; study; Culture; Media; Female; Male; Pentoxifylline; Sperm; Motility; Ovum; Interactions; Spermatozoa; cytology; Support; Non-U.S.Gov't; U.S.Gov't; P.H.S.; browse; non; us; gov't; government; 190
Abstract Electroejaculates from eight snow leopards were used to determine how the motility of spermatozoa was influenced by (i) type of media (Ham's F10, PBS, human tubal fluid or RPMI-1640); (ii) holding temperature (23 degrees C versus 37 degrees C); (iii) washing of spermatozoa and (iv) a sperm metabolic enhancer, pentoxifylline. The duration of sperm motility was assessed by evaluating samples in each treatment every hour for 6 h and a sperm motility index (a value combining percentage sperm motility and rate of forward progression) calculated. Spermatozoa from the Ham's F10, PBS and PBS plus pentoxifylline treatments were also co-incubated with zona-intact, domestic cat eggs that were fixed and evaluated for spermatozoa bound to the zona pellucida, penetrating the outer and inner layers of the zona pellucida and within the perivitelline space. During the 6 h co-incubation, the sperm motility index in PBS with pentoxifylline was greater (P < 0.05) than in PBS alone which, in turn, was greater (P < 0.05) than in the other three test media. Washing the spermatozoa enhanced (P < 0.05) motility in both PBS and PBS plus pentoxifylline relative to unwashed samples, but there was no effect (P > 0.05) of holding temperature. Pentoxifylline supplementation enhanced (P < 0.05) the proportion of cat eggs with bound, but not penetrated, snow leopard spermatozoa in the inner layer of the zona pellucida, and there were no spermatozoa in the perivitelline space.(ABSTRACT TRUNCATED AT 250 WORDS)
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Series Volume Series Issue Edition
ISSN 0022-4251 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 253 Serial 828
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Author Johnston, L.A.; Armstrong, D.L.; Brown, J.L.
Title Seasonal effects on seminal and endocrine traits in the captive snow leopard (Panthera uncia) Type Journal Article
Year (up) 1994 Publication J Reprod Fertil Abbreviated Journal
Volume 102 Issue 1 Pages 229-236
Keywords Animal; Carnivora; physiology; Comparative; study; Fsh; Blood; Gonadotropins; Pituitary; Lh; Male; Seasons; Semen; Sperm; Motility; Spermatozoa; cytology; Testosterone; browse; 180
Abstract The annual reproductive cycle of the male snow leopard (Panthera uncia) was characterized by evaluating seminal and endocrine traits monthly. Testicular volume was greatest (P < 0.05) during the winter months when the quality of ejaculate was optimal. Ejaculate volume, total sperm concentration ml-1, motile sperm concentration per ejaculate, sperm morphology and sperm motility index were lowest during the summer and autumn months compared with the winter and spring. Peripheral LH, FSH and testosterone concentrations were also lowest during the summer months, increasing during the autumn just before the increase in semen quality, and were maximal during the winter months. There was a direct relationship (P < 0.01) between: (1) testosterone and testicular volume, total sperm concentration ml-1, motile sperm concentration per ejaculate and ejaculate volume, and (2) LH and testicular volume and motile sperm concentration per ejaculate. In summary, although spermatozoa were recovered throughout the year, optimal gamete quality was observed during the winter and spring. Although previous studies in felids have demonstrated seasonal effects on either seminal or endocrine traits, this is the first study to demonstrate a distinct effect of season on both pituitary and testicular function.
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ISSN 0022-4251 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 252 Serial 504
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Author Brown, J.L.; Wasser, S.K.; Wildt, D.E.; Graham, L.H.
Title Comparative Aspects of Steroid Hormone Metabolism and Ovarian Activity in Felids, Measured Noninvasively in Feces Type Journal Article
Year (up) 1994 Publication Biol Reprod Abbreviated Journal
Volume 51 Issue 4 Pages 776-786
Keywords Animal; Carbon; Radioisotopes; Carnivora; Cats; Chromatography; High; Pressure; Liquid; Comparative Study; Estradiol; metabolism; Estrone; feces; chemistry; Female; Ovary; physiology; Pregnancy; Progesterone; Pseudopregnancy; Support; Non-U.S.Gov't; browse; non; government; gov't; us; 170
Abstract Noninvasive fecal assays were used to study steroid metabolism and ovarian activity in several felid species. Using the domestic cat (Felis catus) as model, the excretory products of injected [14C]estradiol (E2) and [14C]progesterone (P4) were determined. Within 2 days, 97.0 +/- 0.6% and 96.7 +/- 0.5% of recovered E2 and P4 radioactivity, respectively, was found in feces. E2 was excreted as unconjugated estradiol and estrone (40%) and as a non-enzyme- hydrolyzable conjugate (60%). P4 was excreted primarily as non-enzyme- hydrolyzable, conjugated metabolites (78%) and as unconjugated pregnenolone epimers. A simple method for extracting fecal steroid metabolites optimized extraction efficiencies of the E2 and P4 excretion products (90.1 +/- 0.8% and 87.2 +/- 1.4%, respectively). Analysis of HPLC fractions of extracted fecal samples from the radiolabel-injected domestic cats revealed that E2 immunoreactivity coincided primarily with the unconjugated metabolized [14C]E2 peak, whereas progestogen immunoreactivity coincided with a single conjugated epimer and multiple unconjugated pregnenolone epimers. After HPLC separation, similar immunoreactive E2 and P4 metabolite profiles were observed in the leopard cat (F. bengalensis), cheetah (Acinonyx jubatus), clouded leopard (Neofelis nebulosa), and snow leopard (Panthera uncia). Longitudinal analyses demonstrated that changes in fecal E2 and P4 metabolite concentrations reflected natural or artificially induced ovarian activity. For example, severalfold increases in E2 excretion were associated with overt estrus or exogenous gonadotropin treatment, and elevated fecal P4 metabolite concentrations occurred during pregnant and nonpregnant (pseudopregnant) luteal phases. Although overall concentrations were similar, the duration of elevated fecal P4 metabolites during pseudopregnancy was approximately half that observed during pregnancy. In summary, steroid metabolism mechanisms appear to be conserved among these physically diverse, taxonomically related species. Results indicate that this hormone-monitoring approach will be extremely useful for elucidating the hormonal regulatory mechanism associated with the reproductive cycle, pregnancy, and parturition of intractable and endangered felid species.
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ISSN 0006-3363 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 251 Serial 198
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Author Wack, R.F.; Kramer, L.W.
Title Multifocal osteomyelitis in a young snow leopard (Panthera uncia) Type Journal Article
Year (up) 1995 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume 26 Issue 4 Pages 553-563
Keywords Antibacterial-Drug; Case-Study; diagnosis; Enrofloxacin; Pathophysiology; snow-leopard; veterinary; medical; osteomyelitis; snow leopard; antibacterial; drug; Case; study; snow; leopard; browse; 1370
Abstract A 5-mo-old male snow leopard (Panthera uncia) was presented for mild rear leg lameness. Osteomyelitis was suspected on the basis of radiographic changes and confirmed by histopathology of a biopsy sample from the affected bone. Aerobic cultures of the biopsies repeatedly grew Klebsiella oxytoca. Repeated anaerobic and fungal cultures did not result in growth. The leopard was treated unsuccessfully with cefadroxil, chloramphenicol, and trimethoprim/sulfadiazine despite apparent in vitro sensitivity to these antibiotics. Successful resolution was eventually achieved with enrofloxacin, 7.5 mg/kg p.o. b.i.d. for 60 days. The number of bones involved (right humerus, right and left ulna, right and left radius, right and left femur, right and left tibia, mandible, right metatarsus) made this an unusual presentation of osteomyelitis.
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Notes Document Type: English Approved no
Call Number SLN @ rana @ 277 Serial 997
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Author Jackson, R.; Hunter, D.O.
Title Snow Leopard Survey and Conservation Handbook (2nd Edition) Type Book Whole
Year (up) 1995 Publication Abbreviated Journal
Volume Issue Pages
Keywords surveys; survey; transect; field-study; browse; field study; field; study; 2790
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Publisher ISLT and National Biological Survey Place of Publication Editor
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Notes Approved no
Call Number SLN @ rana @ 281 Serial 454
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Author Hunter, D.
Title Mongolian-American Snow Leopard Project Type Journal Article
Year (up) 1997 Publication Cat News Abbreviated Journal
Volume 26 Issue Pages 15-16
Keywords asia; Mongolia; panthera uncia; endangered; threatened species; mammals; study methods; techniques; telemetry; snow leopard project; distribution; Gobi Desert; threatened; species; snow; leopard; snow-leopard; project; study; methods; panthera; uncia; browse; 630
Abstract A snow leopard project is underway to study snow leopards in Mongolia. The project, called the Mongolian-American Snow Leopard Project, involves the Wildlife Conservation Society, the Mongolian Association for the Conservation of Nature and Environment, the National Geographic Society, the Mongolian Ministry of Nature and the Environment, the U.S. National Biological Service, and the International Snow Leopard Trust. The objective of the study is to survey the distribution and status of Mongolia's snow leopards, including those living in the Gobi Desert. klf.
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Notes AUTHOR ADDRESS: Natl. Biol. Surv., MESC, 4512 McMurray Ave., Fort Collins, CO 80525-3400, NOTES: reprinted from: Snow Line (Intl. Snow Leopard Trust) Vol. XIV, 1996. Document Type: English Call Number: WR97-008333 Approved no
Call Number SLN @ rana @ 310 Serial 392
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