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Author Kazensky, C.A.; Munson, L.; Seal, U.S.
Title The effects of melengestrol acetate on the ovaries of captive wild felids Type Journal Article
Year 1998 Publication Journal-of-Zoo-and-Wildlife-Medicine Abbreviated Journal
Volume (down) 29 Issue 1 Pages 1-5
Keywords Mga; zoo; felids; contraception; Melengestrol-acetate; ovaries; snow-leopard; Panthera-uncia; snow leopard; browse; uncia; panthera; melengestrol; acetate; 1260; effects; study; ovarian; Ovary; captive; wild; wild felid; Wild-Felid; species; Follicle; Cats; cat; recent; Ovulation; doses; Dose; action; Progestin; Disease; veterinary
Abstract Melengestrol acetate (MGA) is the most widely used contraceptive in zoo felids, but the mechanism of contraception and the pathologic effects have not been investigated. For this study, the effects of MGA on folliculogenesis were assessed, and the association of MGA with ovarian lesions was evaluated. Comparisons were made among the histopathologic findings in the ovaries from 88 captive wild felids (representing 15 species) divided into three groups: 37 currently contracepted with MGA, eight previously exposed to MGA, and 43 never contracepted. Ninety-one percent of the felids evaluated had tertiary follicles, and no differences were noted between contracepted and uncontracepted cats. Some MGA-contracepted cats also had corpora lutea indicating recent ovulation. These results indicate that folliculogenesis is not suppressed by current doses of MGA and ovulation occurred in some cats. Therefore, the contraceptive actions of MGA do not occur by suppressing folliculogenesis, and MGA-contracepted felids likely have endogenous estrogens that may confound progestin effects on the uterus. Cystic rete ovarii was the most common pathologic finding, but they were not more prevalent in MGA-contracepted cats. These findings indicate that MGA is not associated with ovarian disease, including ovarian cancer, in contrast to the uterine lesions noted in MGA-treated cats.
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Notes Document Type: English. Affiliation: Taylor Veterinary Hospital, Turlock , California 95382, USA Approved no
Call Number SLN @ rana @ 348 Serial 527
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Author Thorel, M.F.; Karoui, C.; Varnerot, A.; Fleury, C.; Vincent, V.
Title Isolation of Mycobacterium bovis from baboons, leopards and a sea-lion Type Journal Article
Year 1998 Publication Vet Res Abbreviated Journal
Volume (down) 29 Issue 2 Pages 207-212
Keywords Animal; Animals; zoo; Carnivora; microbiology; Case; Report; Cattle; Dna; Fingerprinting; Transposable; Elements; Disease; Outbreaks; veterinary; France; Genome; Bacterial; Germany; Male; Monkey; Diseases; diagnosis; epidemiology; Mycobacterium; Infections; bovis; classification; isolation; purification; Papio; Seals; browse; 440
Abstract This study reports on two series of cases of Mycobacterium bovis infection in zoo animals. The first was in a captive population of baboons (Papio hamadryas) and the second in a mixed group of wild mammals, including four leopards (Panthera uncia and Panthera pardus) and a sea-lion (Otaria byrona). The isolation and identification of strains of M. bovis confirmed the presence of M. bovis infections in both zoos. The epidemiological study using genetic markers such as the IS6110-based DNA fingerprinting system made it possible to differentiate between M. bovis strains. The M. bovis strains isolated from baboons were shown to contain a single IS6110 copy, as usually do cattle isolates, whereas the M. bovis strains isolated from the other exotic animals presented multiple copies. This finding suggests that the origin of the contamination for the baboons in zoo A could be related to cattle. The origin of the contamination for the leopards and sea-lion in zoo B is more difficult to determine. In conclusion, the authors suggest some recommendations for avoiding outbreaks of tuberculosis infections in zoos.
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ISSN 0928-4249 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 346 Serial 966
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Author Munson, L.; Worley, M.B.
Title Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks Type Journal Article
Year 1991 Publication Vet Pathol Abbreviated Journal
Volume (down) 28 Issue 1 Pages 37-45
Keywords Cirrhosis; epidemiology; Hemosiderosis; Hepadnaviridae; Hepatic; Hepatitis; pathology; Veno-Occlusive; veterinary; zoo
Abstract Livers from 54 snow leopards, 4 days to 23 years old, that had died in 23 US zoos, were evaluated histopathologically to determine if the hepatic fibrosis, which has been noted to be prevalent in this species, was due to chronic active hepatitis from hepadnaviral infection, Ito cell proliferation, or hemosiderosis. Forty-two of 54 snow leopards had subintimal vascular fibrosis with partial or total occlusion of central and sublobular veins (veno-occlusive disease) of unknown origin. All 21 leopards older than 5 years were affected. Four leopards had chronic active hepatitis, and 12 leopards had cholangiohepatitis; but these lesions were not connected anatomically to central and sublobular venous fibrosis. Hepatocellular and Kupffer cell siderosis and Ito cell proliferation were prevalent and often coexisted with perisinusoidal, central, and sublobular venous fibrosis; but fibrosis was present in leopards without siderosis or Ito cell proliferation. The pattern and prevalence of veno-occlusive disease in these leopards was similar to that reported in captive cheetah (Acinonyx jubatus), suggesting that a common extrinsic factor may cause the majority of hepatic disease in these large felid animals in captivity.
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 173 Serial 706
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Author Wack, R.F.; Kramer, L.W.
Title Multifocal osteomyelitis in a young snow leopard (Panthera uncia) Type Journal Article
Year 1995 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume (down) 26 Issue 4 Pages 553-563
Keywords Antibacterial-Drug; Case-Study; diagnosis; Enrofloxacin; Pathophysiology; snow-leopard; veterinary; medical; osteomyelitis; snow leopard; antibacterial; drug; Case; study; snow; leopard; browse; 1370
Abstract A 5-mo-old male snow leopard (Panthera uncia) was presented for mild rear leg lameness. Osteomyelitis was suspected on the basis of radiographic changes and confirmed by histopathology of a biopsy sample from the affected bone. Aerobic cultures of the biopsies repeatedly grew Klebsiella oxytoca. Repeated anaerobic and fungal cultures did not result in growth. The leopard was treated unsuccessfully with cefadroxil, chloramphenicol, and trimethoprim/sulfadiazine despite apparent in vitro sensitivity to these antibiotics. Successful resolution was eventually achieved with enrofloxacin, 7.5 mg/kg p.o. b.i.d. for 60 days. The number of bones involved (right humerus, right and left ulna, right and left radius, right and left femur, right and left tibia, mandible, right metatarsus) made this an unusual presentation of osteomyelitis.
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Notes Document Type: English Approved no
Call Number SLN @ rana @ 277 Serial 997
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Author Gosselin, S.J.; Loudy, D.L.; Tarr, M.J.; Balistreri, W.F.; Setchell, K.D.; Johnston, J.O.; Kramer, L.W.; Dresser, B.L.
Title Veno-occlusive disease of the liver in captive cheetah Type Journal Article
Year 1988 Publication Vet Pathol Abbreviated Journal
Volume (down) 25 Issue 1 Pages 48-57
Keywords Animal; Feed; analysis; Carnivora; Cheetahs; Female; Hepatic; Veno; Occlusive; Disease; pathology; veterinary; Histocytochemistry; Liver; ultrastructure; Male; Microscopy; Electron; Support; Non-U.S.Gov't; Vitamin A; browse; non; us; gov't; government; 280
Abstract Liver tissues from 126 captive cheetah were evaluated by light microscopy and histochemistry; eight animals were evaluated by electron microscopy. The main hepatic lesion, a vascular lesion resembling veno- occlusive disease (VOD) of the liver and characterized by subendothelial fibrosis and proliferation of smooth muscle-like cells in the central veins, was seen in 60% of the sexually mature cheetah. Although this hepatic vascular lesion was seen in cheetah as young as 1 year of age, the most severe lesions, usually associated with liver failure, were found in cheetah between the ages of 6 and 11. There was no sex predisposition, and in approximately 40% of the VOD cases, liver disease was not suspected clinically or at necropsy. VOD was found in other felidae, especially in the snow leopard. High levels of vitamin A in livers, as well as in diets of the cheetah, could be a contributing factor in the development of VOD in some groups of cheetah.
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Notes Document Type: Eng Approved no
Call Number SLN @ rana @ 127 Serial 339
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Author Ryan, J.A.; Roudebush, P.; Shores, J.
Title Laryngeal obstruction associated with cuterebrosis in a snow leopard (Felis-uncia) Type Journal Article
Year 1990 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume (down) 21 Issue 3 Pages 346-352
Keywords Cuterebrosis; medecine; veterinary; medical; zoo; zoos; medicine; browse; 1480
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Notes Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no
Call Number SLN @ rana @ 160 Serial 837
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Author Jalanka, H.H.
Title Medetomidine-induced and ketamine-induced immobilization of snow leopards (Panthera uncia) doses, evaluation and reversal by atipamezole Type Journal Article
Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume (down) 20 Issue 2 Pages 154-162
Keywords immobilization; drugs; dossage; doses; medetomidine; ketamine; veterinary; medical; medicine; zoo; zoos; atipamezole; browse; 1500
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Notes Addresses:JALANKA HH, HELSINKI ZOO,SF-00570 HELSINKI,FINLAND Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no
Call Number SLN @ rana @ 146 Serial 484
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Author Calle, P.P.; Colter, S.B.; Taylor, R.A.; Wright, A.M.
Title Extramedullary thoracolumbar fungal (scopulariopsis-brumptii) abscesses in 2 snow leopard (Panthera-uncia) littermates Type Journal Article
Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume (down) 20 Issue 3 Pages 346-353
Keywords medecine; veterinary; medical; zoo; medicine; thoraclumbrar-fungal; browse; 1490
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Call Number SLN @ rana @ 131 Serial 207
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Author Fix, A.S.; Riordan, D.P.; Hill, H.T.; Gill, M.A.; Evans, M.B.
Title Feline panleukopena virus and subsequent canine-distemper virus infection in two snow leopards (Panthera uncia) Type Journal Article
Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume (down) 20 Issue 3 Pages 273-281
Keywords diagnosis; fecal; Fpv; leukemia; panleukopenia; panthera uncia; snow leopard; therapy; vaccination; veterinary; Virus; zoo
Abstract Two adult snow leopards (Panthera uncia), male and female, both with vaccinations current, became infected with feline panleukopenia virus (FPV) at the Blank Park Zoo, Des Moines, Iowa, in late 1988. Clinical signs included weakness, hemorrhagic feces, fever, seizures, and nasal discharge. Blood analysis revealed severe lymphopenia and mild anemia. A positive enzyme-linked immunosorbent assay (ELISA) test for FPV on fecal contents from the male leopard confirmed the diagnosis. In spite of intensive therapy, both animals died. Necropsy of the female, which survived for 1 wk after onset of signs, revealed intestinal crypt necrosis, pulmonary consolidation, necrotizing laryngitis, and diffuse lymphoid depletion. The male leopard, which lived 3 wk after onset of illness, had similar enteric and lymphoid lesions. In addition, there was a severe interstitial pneumonia, with syncytial cells containing eosinophilic intracytoplasmic inclusion bodies. Ultrastructural characteristics of these inclusions featured tubular structures consistent with a paramyxovirus. Although repeated virus isolation attempts from the affected lung were negative, polyclonal and monoclonal fluorescent antibody tests were strongly positive for canine distemper virus (CDV). Frozen paired sera from each leopard demonstrated very high acute and convalescing titers to FPV; both animals also seroconverted to CDV, with titers in the male leopard higher than those in the female. Additional tests for toxoplasmosis, feline infectious peritonitis, feline rhinotracheitis, feline calicivirus, feline leukemia, canine parainfluenza, and bovine respiratory syncytial virus were all negative. The neurologic signs present in these leopards remained unexplained, but may have been attributable to CDV infection. A feral cat trapped on zoo property had feces positive for FPV by ELISA. Although the specific contributions of FPV and CDV toward the development of this case are unknown, it is likely that initial FPV-induced immunosuppression allowed the subsequent development of CDV in these snow leopards. The likelihood that initial FPV infection came from feral cats underscores the importance of feral animal control on zoo premises.
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Notes Addresses:FIX AS, IOWA STATE UNIV SCI & TECHNOL,DEPT VET PATHOL,AMES,IA 50011IOWA STATE UNIV SCI & TECHNOL,VET DIAGNOST LAB,AMES,IA 50011BLANK PK ZOO,DES MOINES,IA 50315NORDEN LABS INC,LINCOLN,NE 68501NATL VET SERV LABS,AMES,IA 50010 Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Connective Phrase: English Approved no
Call Number SLN @ rana @ 147 Serial 277
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Author Jalanka, H.H.
Title Evaluation and comparison of 2 ketamine-based immobilization techniques in snow leopards (Panthera uncia) Type Journal Article
Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal
Volume (down) 20 Issue 2 Pages 163-169
Keywords ketamine; immobilization; capture; veterinary; zoo; zoos; medicine; medical; browse; 1530
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Notes Addresses:JALANKA HH, HELSINKI ZOO,SF-00570 HELSINKI,FINLAND Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no
Call Number SLN @ rana @ 148 Serial 485
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