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Author Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B.
Title Feline papillomas and papillomaviruses Type (down) Journal Article
Year 2000 Publication Vet Pathol Abbreviated Journal
Volume 37 Issue 1 Pages 1-10
Keywords Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120
Abstract Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2).
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 385 Serial 948
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Author Lutz, H.; Hofmann-Lehmann, R.; Fehr, D.; Leutenegger, C.; Hartmann, M.; Ossent, P.; Grob, M.; Elgizoli, M.; Weilenmann, P.
Title Liberation of the wilderness of wild felids bred under human custody: Danger of release of viral infections Type (down) Journal Article
Year 1996 Publication Schweizer Archiv fuer Tierheilkunde Abbreviated Journal
Volume 138 Issue 12 Pages 579-585
Keywords endangered-species; European-Wild-Cat; Fiv; Fpv; Host; Human-Custody; infection; Pathogen; Reintroduction-Projects; Relocation-Projects; survival; Tibet; Veterinary-Medicine; Viral-Disease; Viral-Infection; Wild-Felid; Wild-Felid-Breeding; Wilderness-Liberation; Wildlife-Management; browse; endangered; species; european; wild; cat; Human; custody; reintroduction; project; relocation; veterinary; medicine; Viral; Disease; wild felid; breeding; wilderness; liberation; management; 690
Abstract There are several felidae amongst the numerous endangered species. Means of aiding survival are the reintroduction to the wild of animals bred under the auspices of man and their relocation from densely populated to thinly populated areas. It is unlikely that the dangers of such reintroduction or relocation projects have been examined sufficiently in respect to the risks of virus infections confronting individuals kept in zoos or similar situations. This report presents infections may be expected to occur when relo- three examples to illustrate that accidental virus cating and reintroducing wild cats. The first example is the reintroduction of captive snow leopards. Zoo bred snow leopards may be infected with FIV, a virus infection that is highly unlikely to occur in the original hirnalayan highlands of Tibet and China. A second example is of several cases of FIP that occured in European wild cats bred in groups in captivity. The third example mentioned is the relocation of hons from East Africa where all the commonly known feline viruses are wide-spread to the Etosha National Park. In the latter, virus infections such as FIV, FCV and FPV do not occur. The indiscriminate relocation and reintroduction of the wild cats mentioned here harbours a potential of undesirable consequences.
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Notes Document Type: German Approved no
Call Number SLN @ rana @ 287 Serial 629
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Author Machado, C.; Brown, P.; Turner, R.
Title Dental crown restorations on a snow leopard Type (down) Journal Article
Year 1984 Publication Journal Of Zoo Animal Medicine Abbreviated Journal
Volume 15 Issue 4 Pages 146-150
Keywords dentistry; veterinary; medical; medicine; zoo; zoos; captivity; browse; 1560
Abstract In the spring of 1983 the San Francisco Zoo received a female snow leopard (Panthera uncia) as part of an exotic animal exchange program with the People's Republic of China. Upon examination, it was found that this nine-yea old, seventy-five pound, wild-trapped animal had sustained considerable dental injuries, including fractures of all maxillary and mandibular anterior teeth. The purpose of this paper is to describe the dental procedures undertaken to restore the physiological function of all four canines.
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Notes Addresses:MACHADO C, SAN FRANCISCO ZOO,SAN FRANCISCO,CA Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no
Call Number SLN @ rana @ 74 Serial 633
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Author Maity, B.; Chakraborty, G.; Pradhan, K.K.
Title Toxocariasis in snow leopard (Panthera unica) Type (down) Journal Article
Year 1994 Publication Indian Veterinary Journal Abbreviated Journal
Volume 71 Issue 5 Pages 499-501
Keywords toxocariasis; India; captivity; zoo; medical; medicine; veterinary; browse; 1410
Abstract Spontaneous occurrence of toxocariasis (Toxocaracati) in captive snow leopards with symptoms of diarrhoea, general malaise, letherapy, dehydration, partial or complete anorexia, vomiting with or without expulsion of the ascarid is reported. Response to anthelmintic drug pyrantal pamoate along with antibacterial drug sulphadimethyl pyrimidine and supportive therapy is recorded.
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Notes Document Type: English Approved no
Call Number SLN @ rana @ 238 Serial 639
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Author Karesh, W.B.; Russell, R.
Title Ovarian dysgerminoma in a snow leopard (Panthera uncia) Type (down) Journal Article
Year 1988 Publication Journal Of Zoo Animal Medicine Abbreviated Journal
Volume 19 Issue 4 Pages 223-225
Keywords medicine; ovarian; Dysgerminoma; veterinary; medical; zoos; zoo; browse; 1520
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Notes Addresses:KARESH WB, WOODLAND PK ZOOLOG GARDENS,5500 PHINNEY AVE N,SEATTLE,WA 98103UNIV WASHINGTON,DIV ANIM MED,SEATTLE,WA 98195 Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no
Call Number SLN @ rana @ 115 Serial 515
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Author McVittie, R.
Title Nursing behavior of snow leopard cubs Type (down) Journal Article
Year 1978 Publication Applied-Animal-Ethology Abbreviated Journal
Volume 4 Issue 2 Pages 159-168
Keywords suckling; behavior; veterinary; zoo; zoos; medical; browse; 1580
Abstract Reports that a preliminary project on nursing behavior in 3 young snow leopards revealed 2 phases in suckling pattern: nonnutritive and nutritive. The latter was distinguished by stereotypic rhythmical movements of the ears associated with swallowing. The cubs also demonstrated a teat preference, but the adaptive significance of such preferences and the accompanying agonistic behavior were unclear. (27 ref) (PsycINFO Database Record (c) 2000 APA, all rights reserved)(unassigned)
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Call Number SLN @ rana @ 37 Serial 669
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Author Munson, L.; Worley, M.B.
Title Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks Type (down) Journal Article
Year 1991 Publication Vet Pathol Abbreviated Journal
Volume 28 Issue 1 Pages 37-45
Keywords Cirrhosis; epidemiology; Hemosiderosis; Hepadnaviridae; Hepatic; Hepatitis; pathology; Veno-Occlusive; veterinary; zoo
Abstract Livers from 54 snow leopards, 4 days to 23 years old, that had died in 23 US zoos, were evaluated histopathologically to determine if the hepatic fibrosis, which has been noted to be prevalent in this species, was due to chronic active hepatitis from hepadnaviral infection, Ito cell proliferation, or hemosiderosis. Forty-two of 54 snow leopards had subintimal vascular fibrosis with partial or total occlusion of central and sublobular veins (veno-occlusive disease) of unknown origin. All 21 leopards older than 5 years were affected. Four leopards had chronic active hepatitis, and 12 leopards had cholangiohepatitis; but these lesions were not connected anatomically to central and sublobular venous fibrosis. Hepatocellular and Kupffer cell siderosis and Ito cell proliferation were prevalent and often coexisted with perisinusoidal, central, and sublobular venous fibrosis; but fibrosis was present in leopards without siderosis or Ito cell proliferation. The pattern and prevalence of veno-occlusive disease in these leopards was similar to that reported in captive cheetah (Acinonyx jubatus), suggesting that a common extrinsic factor may cause the majority of hepatic disease in these large felid animals in captivity.
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 173 Serial 706
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Author Paul, H.A.; Bargar, W.L.; Leininger, R.
Title Total hip replacement in a snow leopard Type (down) Journal Article
Year 1985 Publication J Am Vet Med Assoc Abbreviated Journal
Volume 187 Issue 11 Pages 1262-1263
Keywords Animal; Carnivora; surgery; Case; Report; Hip; Dislocation; veterinary; Prosthesis; Male; browse; 310
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ISSN 0003-1488 ISBN Medium
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Call Number SLN @ rana @ 82 Serial 760
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Author Pfeil, A.; Lucker, H.; Pfeil, I.
Title Leiomyoma in the urinary bladder of a female snow leopard (Uncia uncia, Schreber, 1776) Type (down) Journal Article
Year 2004 Publication Tier„rztliche Praxis Kleintiere Abbreviated Journal
Volume 32 Issue 1 Pages 40-44
Keywords Bladder; captive; diagnostic; Female; german; leopard; origin; snow-leopard; snow-leopards; snow leopard; snow leopards; surgery; therapy; uncia; Uncia-uncia; Uncia uncia; urinary; veterinary; zoo
Abstract Summary

A leiomyoma of the urinary bladder in a 14-year-old female snow leopard exhibiting bloody vaginal discharge was removed by partial cystectomy. Gravel (struvite) was found in the urine of the inflammatory bladder. Additionally ovario-hysterectomy was performed. Histological findings showed a glandular-cystic hyperplasia. Tumors of the bladder are very rare in cats. Specifically the benign tumors of the bladder very often have no clinical relevance and rarely result in bladder dysfunction. Therefore they might remain undiagnosed in many cases, particularly since the diagnostic procedure in big cats is very extensive. Leiomyoma of the bladder in snow leopards have not been described yet. The present paper describes the surgery performed, the succeeding therapy, the struvit prophylaxis, and discusses the aetiology of the leiomyoma's origin on the basis of current literature. Zusammenfassung

Bei einer 14-j„hrigen Schneeleopardin mit blutigem Vaginalausfluss wurde ein Leiomyom der Blase durch partielle Zystektomie entfernt. Im Urin und in der entzndeten Blase konnte Grieá (Struvit) nachgewiesen werden. Gleichzeitig wurde eine Ovariohysterektomie durchgefhrt. Der histologische Befund ergab eine glandul„r-zystische Hyperplasie des Endometriums. Tumoren der Harnblase sind bei Katzen sehr selten. Vor allem benigne Blasentumoren haben oft keine klinische Relevanz und fhren selten zu Blasenfunktionsst”rungen. Es ist daher m”glich, dass sie insbesondere bei Groákatzen wegen der aufwendigen Diagnostik bersehen werden. Leiomyome in der Blase sind beim Schneeleoparden bisher nicht beschrieben. In diesem Artikel werden die durchgefhrte Operation, die folgende Therapie und Struvitprophylaxe beschrieben sowie m”gliche Žtiologien der Entstehung des Leiomyoms anhand der Literatur diskutiert.
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Notes In German. Title: Leiomyom in der Blase bei einem weiblichen Schneeleoparden (Uncia uncia, Schreber, 1776). Aus dem Zoologischen Garten Dresden (Direktor: Dr. H. Lcker) und der Tier„rztlichen Klinik Dr. I. Pfeil, Dresden. Approved no
Call Number SLN @ rana @ 1055 Serial 772
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Author Pollock, R.V.; Carmichael, L.E.
Title Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus Type (down) Journal Article
Year 1983 Publication Am J Vet Res Abbreviated Journal
Volume 44 Issue 2 Pages 169-175
Keywords Animal; Antibodies; Viral; biosynthesis; Dog; Diseases; microbiology; prevention; control; Dogs; Dose; Response; Relationship; Immunologic; Parvoviridae; immunology; Parvovirus; Feline; growth; development; Support; Non-U.S.Gov't; Vaccines; Attenuated; Virus; veterinary; Replication; browse; 350
Abstract Modified live feline panleukopenia virus (FPLV) vaccine protected dogs against canine parvovirus (CPV) infection. However, unlike the long- lived (greater than or equal to 20-month) immunity engendered by CPV infection, the response of dogs to living FPLV was variable. Doses of FPLV (snow leopard strain) in excess of 10(5.7) TCID50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. The duration of immunity, as measured by the persistence of hemagglutination-inhibiting antibody, was related to the magnitude of the initial response to vaccination; dogs with vigorous initial responses resisted oronasal CPV challenge exposure 6 months after vaccination, and hemagglutination-inhibiting antibodies persisted in such dogs for greater than 1 year. Limited replication of FPLV in dogs was demonstrated, but unlike CPV, the feline virus did not spread to contact dogs or cats. Adverse reactions were not associated with living FPLV vaccination, and FPLV did not interfere with simultaneous response to attenuated canine distemper virus.
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ISSN 0002-9645 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 69 Serial 784
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