Abstract: The snow leopard faces multiple threats in the Himalayan region, from habitat degradation, loss of prey, the trade in pelts, parts and live animals, and conflict with humans, primarily pastoralists. Consequently, the populations are considered to be in decline and the species is listed as Endangered in the IUCN's Red List. As a 'flagship' and 'umbrella' species the snow leopard can be a unifying biological feature to raise awareness of its plight and the need for conservation, which will benefit other facets of Himalayan biodiversity as well. Some studies of snow leopards have been conducted in the Himalayan region. But, because of its elusive nature and preference for remote and inaccessible habitat, knowledge of the ecology and behaviour of this mystical montane predator is scant. The available information, however, suggests that snow leopards occur at low densities and large areas of habitat are required to conserve a viable population. Thus, many researchers and conservationists have advocated landscape-scale approaches to conservation within a regional context, rather than focusing on individual protected areas.This regional strategy for WWF's snow leopard conservation program is built on such an approach. The following were identified as important regional issues: 1) international trade in snow leopards and parts; 2) the human-snow leopard conflict; 3) the need for a landscape approach to conservation to provide large spatial areas that can support demographically and ecologically viable snow leopard metapopulations; 4) research on snow leopard ecology to develop long-term, science-based conservation management plans; and 5) regional coordination and dialog. While the issues are regional, the WWF's in the region have developed 5-year strategic actions and activities, using the regional strategies as a touchstone, which will be implemented at national levels. The WWF's will develop proposals based on these strategic actions, with estimated budgets, for use by the network for funding and fund-raising. WWF also recognizes the need to collaborate and coordinate within the network and with other organizations in the region to achieve conservation goals in an efficient manner, and will form a working group to coordinate activities and monitor progress.

Abstract: An expert evaluation of the numbers of snow leopard and its preys, Siberian ibex and long-tailed marmot, was made on the basis of surveys conducted in Hissar nature reserve in 1999. The total number of the snow leopard is estimated at 12-16 individuals, whereas that of the Siberian ibex at 1000 individuals. An average density of the population of the long tailed marmot ranges at 4,8 individuals per ha. The ratio of the numbers between the snow leopard, Siberian ibex and long tailed marmot is 1:68:450. The major threats for the snow leopard are poaching on the borders of the nature reserve, a decrease in of preys, shrinking of the range in areas adjoining the nature reserve as a result of intensification of industrial activities and disturbing factors. For the Siberian ibex and long tailed marmot the major limiting factors are the shrinking of the areas and deterioration of the forage value of the high-mountain pastures, as well as the direct competition for forage with domestic animals at the sites adjoining the territory of the nature, as well as disturbing factors.

Abstract: Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2).