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Author | Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B. | ||||
Title | Feline papillomas and papillomaviruses | Type | Journal Article | ||
Year | 2000 | Publication | Vet Pathol | Abbreviated Journal | |
Volume | 37 | Issue | 1 | Pages | 1-10 |
Keywords | Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120 | ||||
Abstract | Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2). | ||||
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Language | Summary Language | Original Title | |||
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ISSN | 0300-9858 | ISBN | Medium | ||
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Document Type: eng | Approved | no | ||
Call Number | SLN @ rana @ 385 | Serial | 948 | ||
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Author | Trepanier, L.A.; Cribb, A.E.; Spielberg, S.P.; Ray, K. | ||||
Title | Deficiency of cytosolic arylamine N-acetylation in the domestic cat and wild felids caused by the presence of a single NAT1-like gene | Type | Journal Article | ||
Year | 1998 | Publication | Pharmacogenetics | Abbreviated Journal | |
Volume | 8 | Issue | 2 | Pages | 169-179 |
Keywords | Acetylation; Amino; Acid; Sequence; Animal; Arylamine; N-Acetyltransferase; metabolism; Base; Blotting; Southern; Carnivora; genetics; Cats; Cytosol; enzymology; Dna; Human; Isoenzymes; Liver; Molecular; Data; Polymerase; Chain; Reaction; Rabbits; Homology; Nucleic Acid; Substrate; Specificity; Support; U.S.Gov't; P.H.S.; browse; nucleic; us; government; 130 | ||||
Abstract | The purpose of this study was to determine the molecular basis for a relative deficiency in the cat of cytosolic arylamine N- acetyltransferase (NAT), an enzyme family that is important in the metabolism of xenobiotics and that normally consists of at least two related enzymes, NAT1 and NAT2. N-acetyltransferase in feline liver showed high affinity (mean Km = 2.1 microM) for p-aminobenzoic acid, an NAT1 selective substrate in humans and rabbits, but showed a very poor affinity (mean Km > 10 mM) for sulfamethazine, an NAT2 selective substrate in humans and rabbits. Immunoreactive N-acetyltransferase was detected in feline liver, bladder and colon using an NAT1-specific antipeptide antibody, but was not detected in any tissues using an NAT2- specific antibody. Southern blot analysis of genomic DNA demonstrated a single band in domestic cats using each of six restriction digests; single bands were also found on Southern blot analysis of six wild felids. The deduced amino acid sequence of the central portion of feline N-acetyltransferase, obtained by polymerase chain reaction amplification in both domestic cats and seven wild felids (lion, tiger, lynx, snow leopard, bobcat, Asian leopard cat and cheetah), contained three residues, Phe125, Arg127, and Tyr129, which determine NAT1-like substrate specificity in humans. These results support the conclusion that cytosolic arylamine N-acetylation activity is low in the cat because of the presence of a single N-acetyltransferase that has substrate specificity, immunogenicity and sequence characteristics similar to human NAT1, and that the unusual presence of only a single N- acetyltransferase gene appears to be a family wide trait shared by other felids. | ||||
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Series Volume | Series Issue | Edition | |||
ISSN | 0960-314x | ISBN | Medium | ||
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Document Type: eng | Approved | no | ||
Call Number | SLN @ rana @ 345 | Serial | 968 | ||
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Author | Brown, J.L.; Wasser, S.K.; Wildt, D.E.; Graham, L.H. | ||||
Title | Comparative Aspects of Steroid Hormone Metabolism and Ovarian Activity in Felids, Measured Noninvasively in Feces | Type | Journal Article | ||
Year | 1994 | Publication | Biol Reprod | Abbreviated Journal | |
Volume | 51 | Issue | 4 | Pages | 776-786 |
Keywords | Animal; Carbon; Radioisotopes; Carnivora; Cats; Chromatography; High; Pressure; Liquid; Comparative Study; Estradiol; metabolism; Estrone; feces; chemistry; Female; Ovary; physiology; Pregnancy; Progesterone; Pseudopregnancy; Support; Non-U.S.Gov't; browse; non; government; gov't; us; 170 | ||||
Abstract | Noninvasive fecal assays were used to study steroid metabolism and ovarian activity in several felid species. Using the domestic cat (Felis catus) as model, the excretory products of injected [14C]estradiol (E2) and [14C]progesterone (P4) were determined. Within 2 days, 97.0 +/- 0.6% and 96.7 +/- 0.5% of recovered E2 and P4 radioactivity, respectively, was found in feces. E2 was excreted as unconjugated estradiol and estrone (40%) and as a non-enzyme- hydrolyzable conjugate (60%). P4 was excreted primarily as non-enzyme- hydrolyzable, conjugated metabolites (78%) and as unconjugated pregnenolone epimers. A simple method for extracting fecal steroid metabolites optimized extraction efficiencies of the E2 and P4 excretion products (90.1 +/- 0.8% and 87.2 +/- 1.4%, respectively). Analysis of HPLC fractions of extracted fecal samples from the radiolabel-injected domestic cats revealed that E2 immunoreactivity coincided primarily with the unconjugated metabolized [14C]E2 peak, whereas progestogen immunoreactivity coincided with a single conjugated epimer and multiple unconjugated pregnenolone epimers. After HPLC separation, similar immunoreactive E2 and P4 metabolite profiles were observed in the leopard cat (F. bengalensis), cheetah (Acinonyx jubatus), clouded leopard (Neofelis nebulosa), and snow leopard (Panthera uncia). Longitudinal analyses demonstrated that changes in fecal E2 and P4 metabolite concentrations reflected natural or artificially induced ovarian activity. For example, severalfold increases in E2 excretion were associated with overt estrus or exogenous gonadotropin treatment, and elevated fecal P4 metabolite concentrations occurred during pregnant and nonpregnant (pseudopregnant) luteal phases. Although overall concentrations were similar, the duration of elevated fecal P4 metabolites during pseudopregnancy was approximately half that observed during pregnancy. In summary, steroid metabolism mechanisms appear to be conserved among these physically diverse, taxonomically related species. Results indicate that this hormone-monitoring approach will be extremely useful for elucidating the hormonal regulatory mechanism associated with the reproductive cycle, pregnancy, and parturition of intractable and endangered felid species. | ||||
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Series Volume | Series Issue | Edition | |||
ISSN | 0006-3363 | ISBN | Medium | ||
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Document Type: eng | Approved | no | ||
Call Number | SLN @ rana @ 251 | Serial | 198 | ||
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Author | Sunquist, F. | ||||
Title | Where cats and herders mix. (snow leopards in Tibet and Mongolia) | Type | Journal Article | ||
Year | 1997 | Publication | International Wildlife | Abbreviated Journal | |
Volume | 27 | Issue | 1 | Pages | 27-33 |
Keywords | Mongolia; Tibet; herder; livestock; snow-leopard; predator; prey; World-Wildlife-Foundation; habitat; reserve; park; refuge; Pakistan; China; herders; parks; protected-area; snow leopard; browse; Wwf; world wildlife foundation; 1110; snow; leopard; range; territory; central; Central Asia; asia; Animal; region; conservation; wildlife; foundation; border; sheep; Baltistan; enclosures; area; home; snow leopards; snow-leopards; leopards; countries; country; Feed; Cats; cat; mountain; peoples; people | ||||
Abstract | The snow leopard inhabits a huge range of territory which encompasses some of Central Asia's most bleak and inhospitable terrains. The animal herders in these regions are desperately poor and yet they have agreed to cooperate with conservation groups in protecting the snow leopard. The World Wildlife Foundation has worked to create a refuge on the Pakistan-China border. Sheep herders near Askole, a village in the Baltistan region of northern Paksitan, drive their flocks past stone enclosures. The area is also home to snow leopards. With their natural prey dminished, leopards in 13 countries of central Asia occasionally feed on livestock, putting the cats on a collision course with mountain peoples. | ||||
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COPYRIGHT 1997 National Wildlife Federation , Jan-Feb 1997 v27 n1 p26(8) Document Type: English | Approved | no | ||
Call Number | SLN @ rana @ 330 | Serial | 950 | ||
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Author | Meiers, S.T. | ||||
Title | Habitat use by captive puma (Felis concolor) and snow leopards (Pathera uncia) at the Lincoln Park Zoo, Chicago, Illinois | Type | Book Whole | ||
Year | 1992 | Publication | Abbreviated Journal | ||
Volume | Issue | Pages | 1-74 | ||
Keywords | habitat; habitat use; use; captive; felis; Felis-concolor; concolor; snow; snow leopards; snow leopard; snow-leopards; snow-leopard; leopards; leopard; uncia; park; zoo; 1990; observations; panthera; panthera uncia; Panthera-uncia; zoological; zoological gardens; zoological-gardens; gardens; behavior; species; Time budget; dens; Identity; Animals; Animal; non; Cats; cat; location; relief | ||||
Abstract | Between May 1990 and January 1991, behavioral observations were made of two captive pumas (Felis concolor Linnaeus), and two captive snow leopards (Panthera uncia Schreber) in their outdoor exhibits at the Lincoln Park Zoological Gardens, Chicago, Illinois. Behaviors compared within and between species included: 1) time spend in the different habitat types; 2) time budgets for the different behaviors: laying, moving, sitting, standing, crouching, in the tree, drinking, urinating, defecating, within their inside dens, and “behavior not determined” when the identity or behavior of the individuals could not be determined; and 3) mobility of the animals within their exhibits. Also examined were: 4) preferences for different habitat types; 5) recommendations for future exhibit designs. Both species located themselves within their exhibits in a non-random manner. The majority of cats' time was spent in elevated locations (i.e., gunite ledges approximately 1-5.5 m above ground-level). Snow leopards exhibited this tendency to a greater extent than did the pumas. Both species also spent the majority of their time in the lying-down behavior; again snow leopards displayed this tendency significantly more than the pumas. Pumas were highly mobile and changed locations and behaviors in their exhibit significantly more than the snow leopards. No significant differences were noted between conspecifics in regard to habitat type preference, or mobility within the exhibit. Suggestions for future exhibit design include elevated locations for the cats to lay and look around within and outside their exhibits, caves for access to shade or relief from inclement weather, and ground surfaces to move about on. Features for exhibit design should take into consideration the natural habitat of the cat to occupy the exhibit. | ||||
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Corporate Author | Thesis | Ph.D. thesis | |||
Publisher | DePaul University | Place of Publication | Editor | ||
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A thesis submitted to the faculty of the Department of Biological Sciences in partial fulfillment of the degree requirements for the degree of Master of Science at DePaul University. | Approved | no | ||
Call Number | SLN @ rana @ 1008 | Serial | 673 | ||
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Author | Ferretti, F., Lovari, S. | ||||
Title | Predation may counteract climatic change as a driving force for movements of mountain ungulates | Type | Report | ||
Year | 2016 | Publication | Behavioural-Processes | Abbreviated Journal | |
Volume | Issue | 129 | Pages | 101-104 | |
Keywords | Climate change, Environmental change, Interspecific interactions, Large cats, Predator-prey interactions | ||||
Abstract | Temperature variations are expected to influence altitudinal movements of mountain herbivores and, in turn, those of their predators, but relevant information is scarce. We evaluated monthly relationships between temperature and altitude used by a large mountain-dwelling herbivore, the Himalayan tahr Hemitragus jemlahicus, and its main predator, the snow leopard Panthera uncia, in an area of central Himalaya for five consecutive years (2006–2010). In contrast to expectations, there was no significant direct relationship between altitude of tahr sightings and temperature. The mean altitude of tahr sightings decreased by c. 200 m throughout our study. As expected, snow leopard movements tracked those of tahr, although the core area of the snow leopard did not move downwards. Tahr remained the staple of the snow leopard diet: we suggest that the former did not move upwards in reaction to higher temperature to avoid encounters with the latter. Avoidance of competition with the larger common leopard Panthera pardus at lower altitudes could explain why snow leopards did not shift their core area downwards. Apparently, interspecific interactions (predation; competition) influenced movements of Himalayan tahr and snow leopards more than climatic variations. |
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Call Number | SLN @ rakhee @ | Serial | 1441 | ||
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Author | McCarthy, T.; Khan, J.; Ud-Din, J.; McCarthy, K. | ||||
Title | First study of snow leopards using GPS-satellite collars underway in Pakistan | Type | Journal Article | ||
Year | 2007 | Publication | Cat News | Abbreviated Journal | |
Volume | 46 | Issue | Spring | Pages | 22-23 |
Keywords | study; snow; snow leopards; snow leopard; snow-leopards; snow-leopard; leopards; leopard; using; collars; collar; Pakistan; uncia; Uncia uncia; Uncia-uncia; habitat; Cats; cat; sound; knowledge; ecology; behavior; conserve; information; radio; radio collars; radio collar; radio-collars; radio-collar; Nepal; 1980; Mongolia; 1990; Gps; Report; Data; Satellite | ||||
Abstract | Snow leopards (Uncia uncia) are highly cryptic and occupy remote inaccessible habitat, making studying the cats difficult in the extreme. Yet sound knowledge of the cat's ecology, behavior and habitat needs is required to intelligently conserve them. This information is lacking for snow leopards, and until recently so was the means to fill that knowledge gap. Two long-term studies of snow leopards using VHF radio collars have been undertaken in Nepal (1980s) and Mongolia (1990s) but logistical and technological constraints made the findings of both studies equivocal. Technological advances in the interim, such as GPS collars which report data via satellite, make studies of snow leopards more promising, at least in theory. | ||||
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Call Number | SLN @ rana @ 1009 | Serial | 666 | ||
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Author | Jackson, R. | ||||
Title | Snow Cats of Nepal's Langue Gorge | Type | Journal Article | ||
Year | 1987 | Publication | Animal Kingdom | Abbreviated Journal | |
Volume | 4 | Issue | Pages | 44-53 | |
Keywords | Nepal; tracking; home-range; habitat; home range; home; range; browse; 3630; snow; Cats; cat; gorge | ||||
Abstract | Anecdotal account with some general research results of a four year tracking study of the snow leopard in Nepal's Langu valley | ||||
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Call Number | SLN @ rana @ 111 | Serial | 439 | ||
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Author | Green, R. | ||||
Title | Toxoplasmosis: Blood disease in cats can strike man as well | Type | Newspaper Article | ||
Year | 1977 | Publication | Seattle Times | Abbreviated Journal | |
Volume | Issue | Pages | |||
Keywords | Blood; Disease; Cats; cat | ||||
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Call Number | SLN @ rana @ 1087 | Serial | 352 | ||
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