Abstract: In this study, we investigated the cross-reactivity pattern of IgE and IgG4 antibodies to the major feline allergen, Fel d I. We studied the IgE and IgG4 response of 11 cat-allergic patients against Fel d I-like structures in eight members of the Felidae family: ocelot, puma, serval, siberian tiger, lion, jaguar, snow leopard, and caracal. Hair from these “big cats” was collected, extracted, and used in a RAST system and histamine-release test. By means of a RAST-inhibition assay with affinity-purified Fel d I from cat dander, it was established that, in the Felidae species, a Fel d I equivalent is present that reacts with IgE and IgG4 antibodies. We found that all patients had cross-reacting IgE antibodies to seven of the Felidae tested; no IgE antibodies reactive with the caracal were found. Eight of 10 patients with IgG4 antibodies directed to cat dander also had IgG4 antibodies directed to several Felidae species, including the caracal. However, the correlation between the IgE and the IgG4 antibody specificity was low, indicating that, in the case of Fel d I IgE and IgG4, antibodies do not necessarily have the same specificity.

Abstract: Pastoralism and predation are two major concomitantly known facts and matters of concern for conservation biologists worldwide. Pastoralist-predator conflict constitutes a major social-ecological concern in the Pamir mountain range encompassing Afghanistan, Pakistan, and Tajikistan, and affects community attitudes and tolerance toward carnivores. Very few studies have been conducted to understand the dynamics of livestock predation by large carnivores like snow leopards (Panthera uncia) and wolves (Canis
lupus), owing to the region�s remoteness and inaccessibility. This study attempts to assess the intensity of livestock predation (and resulting perceptions) by snow leopards and wolves across the Afghani, Pakistani, and Tajik Pamir range during the period January 2008�June 2012. The study found that livestock mortality due to disease is the most serious threat to livestock (an average 3.5 animal heads per household per year) and ultimately to the rural economy (an average of US$352 per household per year) as compared to
predation (1.78 animal heads per household per year, US$191) in the three study sites. Overall, 1419 (315 per year) heads of livestock were reportedly killed by snow leopards (47%) and wolves (53%) in the study sites. People with comparatively smaller landholdings and limited earning options, other than livestock rearing, expressed negative attitudes toward both wolves and snow leopards and vice versa. Education was found to be an effective solution to dilute people�s hatred for predators. Low public tolerance of the wolf and
snow leopard in general explained the magnitude of the threat facing predators in the Pamirs. This will likely continue unless tangible and informed conservation measures like disease control and predation compensation programs are taken among others.

Abstract: Afghanistan’s position in latitude, geography and at the intersection of three biogeographic realms has resulted in a surprising biodiversity. Its wildlife includes species such as the snow leopard, Asiatic black bear, Marco Polo sheep, markhor and greater flamingo. Principal threats include high levels of deforestation, land encroachment and hunting for food and trade. Continuing security issues have also made it difficult to monitor species abundance and population trends. Over the last decade, however, survey efforts have provided the first collection of species and habitat data since the late 1970s. Initial findings are enabling the Government and rural communities to begin implementing important conservation measures. This process has included policy development and protected area planning, promoting alternative livelihoods and responsible community management, and continuing research into the status of biodiversity in the field.

Abstract: Prior to the last two decades of conflict, Afghanistan's Wakhan Corridor was considered an important area for conservation of the wildlife of high altitudes. We conducted an assessment of the status of large mammals in Wakhan after 22 years of conflict, and also made a preliminary assessment of wildlife trade
in the markets of Kabul, Faizabad and Ishkashem. The survey confirmed the continued occurrence of at least eight species of large mammals in Wakhan, of which the snow leopard Uncia uncia and Marco Polo sheep Ovis ammon are globally threatened. We found evidence of human-wildlife conflict in Wakhan due to livestock depredation by snow leopard and wolf Canis lupus. Large mammals are hunted for meat, sport, fur, and in retaliation against livestock depredation. The fur trade in Kabul is a threat to the snow leopard, wolf, lynx Lynx lynx and common leopard Panthera pardus.

Abstract: Notes personal sighting and several reports of other recent sightings of snow leopard in Afganastan. Some comments on its distribution in the country