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Author |
Chandra, S.; Laughlin, D.C. |
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Title |
Virus-like particles in cystic mammary adenoma of a snow leopard |
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Journal Article |
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Year |
1975 |
Publication |
Cancer Res |
Abbreviated Journal |
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Volume |
35 |
Issue |
11 Pt 1 |
Pages |
3069-3074 |
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Keywords  |
Adenoma pathology veterinary; Animal; Animals; zoo; Carnivora; Cytoplasmic Granules; Endoplasmic Reticulum: ultrastructure; Inclusion Bodies; Mammae: pathology; Neoplasms: pathology: veterinary; neoplasms; pathology; mammae; inclusion; bodies; ultrastructure; reticulum; endoplasmic; granules; cytoplasmic; adenoma; veterinary; browse; 380 |
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Abstract |
Virus-like particles were observed in the giant cells of a mammary adenoma of a snow leopard kept in captivity. Particles that measured 115 to 125 nm in diameter budded from the lamella of endoplasmic reticulum and were studded on their inner surfaces with dense granules (approximately 12 nm) that gave them their unique ultrastructural morphology. Such particles were not observed extracellularly. Type B or type C particles were not seen in the tumor tissue. |
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0008-5472 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 27 |
Serial |
212 |
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Author |
Doster, A.R.; Armstrong, D.L.; Bargar, T.W. |
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Title |
Seminoma and parathyroid adenoma in a snow leopard (Panthera unica) |
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Journal Article |
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Year |
1989 |
Publication |
J Comp Pathol |
Abbreviated Journal |
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Volume |
100 |
Issue |
4 |
Pages |
475-480 |
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Keywords |
Adenoma: pathology: veterinary; Animal; Carnivora; Dysgerminoma; pathology; veterinary; Male; Microscopy; Electron; neoplasms; Multiple Primary; Parathyroid; Testicular Neoplasms; adenoma; multiple; primary; Testicular; browse; 250 |
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Abstract |
A seminoma and parathyroid adenoma were diagnosed in an aged snow leopard. The ultrastructural appearance of the seminoma was similar to that described in the dog and in man. The lack of significant amounts of rough endoplasmic reticulum, Golgi complexes and free ribosomes in the parathyroid adenoma suggested that it was non-functional. Parathyroid adenoma has not been previously described in a large wild feline. |
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0021-9975 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 142 |
Serial |
244 |
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Author |
Kolmstetter, C.; Munson, L.; Ramsay, E.C. |
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Title |
Degenerative spinal disease in large felids |
Type |
Journal Article |
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Year |
2000 |
Publication |
J Zoo Wildl Med |
Abbreviated Journal |
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Volume |
31 |
Issue |
1 |
Pages |
15-19 |
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Keywords |
Age-Factors; Animal; Animals; zoo; Autopsy; veterinary; Carnivora; Female; Lions; Male; Age; factor; browse; 110 |
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Abstract |
Degenerative spinal disorders, including intervertebral disc disease and spondylosis, seldom occur in domestic cats. In contrast, a retrospective study of 13 lions (Panthera leo), 16 tigers (Panthera tigris), 4 leopards (Panthera pardis), 1 snow leopard (Panthera uncia), and 3 jaguars (Panthera onca) from the Knoxville Zoo that died or were euthanatized from 1976 to 1996 indicated that degenerative spinal disease is an important problem in large nondomestic felids. The medical record, radiographic data, and the necropsy report of each animal were examined for evidence of intervertebral disc disease or spondylosis. Eight (three lions, four tigers, and one leopard) animals were diagnosed with degenerative spinal disease. Clinical signs included progressively decreased activity, moderate to severe rear limb muscle atrophy, chronic intermittent rear limb paresis, and ataxia. The age at onset of clinical signs was 10-19 yr (median = 18 yr). Radiographic evaluation of the spinal column was useful in assessing the severity of spinal lesions, and results were correlated with necropsy findings. Lesions were frequently multifocal, included intervertebral disc mineralization or herniation with collapsed intervertebral disc spaces, and were most common in the lumbar area but also involved cervical and thoracic vertebrae. Marked spondylosis was present in the cats with intervertebral disc disease, presumably subsequent to vertebral instability. Six of the animals' spinal cords were examined histologically, and five had acute or chronic damage to the spinal cord secondary to disc protrusion. Spinal disease should be suspected in geriatric large felids with decreased appetite or activity. Radiographic evaluation of the spinal column is the most useful method to assess the type and severity of spinal lesions. |
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ISSN |
1042-7260 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 384 |
Serial |
545 |
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Author |
White, S.D.; Stannard, A.A.; Ihrke, P.J.; Rosser, E.J. |
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Title |
Therapy of demodicosis in snow leopard challenged |
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Journal Article |
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Year |
1981 |
Publication |
J Am Vet Med Assoc |
Abbreviated Journal |
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Volume |
178 |
Issue |
9 |
Pages |
877-878 |
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Keywords |
Amoxicillin: therapeutic use; Animal; Animals; zoo; Calcium: therapeutic use; Carnivora; Mite Infestations: drug therapy; veterinary; Sulfides: therapeutic use; Thiosulfates: therapeutic use; amoxicillin; therapeutic; calcium; mite; infestations; drug; therapy; drug therapy; sulfides; thiosulfates; browse; use; 360 |
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ISSN |
0003-1488 |
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Document Type: eng |
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no |
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Call Number |
SLN @ rana @ 57 |
Serial |
1020 |
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Author |
Schmidt, R.E.; Eisenbrandt, D.L.; Hubbard, G.B. |
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Title |
Tyzzer's disease in snow leopards |
Type |
Journal Article |
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Year |
1984 |
Publication |
J Comp Pathol |
Abbreviated Journal |
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Volume |
94 |
Issue |
1 |
Pages |
165-167 |
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Keywords |
Animal; Animals; Newborn; zoo; Bacillus; Bacterial; Infections; pathology; veterinary; Carnivora; Liver; browse; 330 |
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Abstract |
Tyzzer's disease was diagnosed histologically in 2 litters of newborn snow leopard kittens. The gross and histological lesions were similar to those reported in domestic cats and other animals. No signs of illness was noted in either of the snow leopard dams. |
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0021-9975 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 67 |
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875 |
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Author |
Thorel, M.F.; Karoui, C.; Varnerot, A.; Fleury, C.; Vincent, V. |
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Title |
Isolation of Mycobacterium bovis from baboons, leopards and a sea-lion |
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Journal Article |
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Year |
1998 |
Publication |
Vet Res |
Abbreviated Journal |
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Volume |
29 |
Issue |
2 |
Pages |
207-212 |
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Keywords |
Animal; Animals; zoo; Carnivora; microbiology; Case; Report; Cattle; Dna; Fingerprinting; Transposable; Elements; Disease; Outbreaks; veterinary; France; Genome; Bacterial; Germany; Male; Monkey; Diseases; diagnosis; epidemiology; Mycobacterium; Infections; bovis; classification; isolation; purification; Papio; Seals; browse; 440 |
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Abstract |
This study reports on two series of cases of Mycobacterium bovis infection in zoo animals. The first was in a captive population of baboons (Papio hamadryas) and the second in a mixed group of wild mammals, including four leopards (Panthera uncia and Panthera pardus) and a sea-lion (Otaria byrona). The isolation and identification of strains of M. bovis confirmed the presence of M. bovis infections in both zoos. The epidemiological study using genetic markers such as the IS6110-based DNA fingerprinting system made it possible to differentiate between M. bovis strains. The M. bovis strains isolated from baboons were shown to contain a single IS6110 copy, as usually do cattle isolates, whereas the M. bovis strains isolated from the other exotic animals presented multiple copies. This finding suggests that the origin of the contamination for the baboons in zoo A could be related to cattle. The origin of the contamination for the leopards and sea-lion in zoo B is more difficult to determine. In conclusion, the authors suggest some recommendations for avoiding outbreaks of tuberculosis infections in zoos. |
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0928-4249 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 346 |
Serial |
966 |
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Author |
Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B. |
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Title |
Feline papillomas and papillomaviruses |
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Journal Article |
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Year |
2000 |
Publication |
Vet Pathol |
Abbreviated Journal |
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Volume |
37 |
Issue |
1 |
Pages |
1-10 |
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Keywords |
Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120 |
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Abstract |
Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2). |
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0300-9858 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 385 |
Serial |
948 |
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Author |
Pollock, R.V.; Carmichael, L.E. |
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Title |
Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus |
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Journal Article |
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Year |
1983 |
Publication |
Am J Vet Res |
Abbreviated Journal |
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Volume |
44 |
Issue |
2 |
Pages |
169-175 |
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Keywords |
Animal; Antibodies; Viral; biosynthesis; Dog; Diseases; microbiology; prevention; control; Dogs; Dose; Response; Relationship; Immunologic; Parvoviridae; immunology; Parvovirus; Feline; growth; development; Support; Non-U.S.Gov't; Vaccines; Attenuated; Virus; veterinary; Replication; browse; 350 |
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Modified live feline panleukopenia virus (FPLV) vaccine protected dogs against canine parvovirus (CPV) infection. However, unlike the long- lived (greater than or equal to 20-month) immunity engendered by CPV infection, the response of dogs to living FPLV was variable. Doses of FPLV (snow leopard strain) in excess of 10(5.7) TCID50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. The duration of immunity, as measured by the persistence of hemagglutination-inhibiting antibody, was related to the magnitude of the initial response to vaccination; dogs with vigorous initial responses resisted oronasal CPV challenge exposure 6 months after vaccination, and hemagglutination-inhibiting antibodies persisted in such dogs for greater than 1 year. Limited replication of FPLV in dogs was demonstrated, but unlike CPV, the feline virus did not spread to contact dogs or cats. Adverse reactions were not associated with living FPLV vaccination, and FPLV did not interfere with simultaneous response to attenuated canine distemper virus. |
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0002-9645 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 69 |
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784 |
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Author |
Chaudhuri, S.; Mukherjee, S.K.; Chatterjee, A.; Ganguli, J.L. |
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Title |
Isolation of P multocida F-3, 4 from a stillborn snow leopard |
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Journal Article |
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Year |
1992 |
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Vet Rec |
Abbreviated Journal |
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130 |
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2 |
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36 |
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Animal; Bacteremia; Blood; browse; Carnivora; Death; Diseases; Female; Fetal; Infections; isolation; microbiology; multocida; Pasteurella; Pregnancy; purification; veterinary |
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0042-4900 |
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Document Type: eng |
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SLN @ rana @ 187 |
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214 |
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Author |
Kleinman, M.S.; Garman, R.H. |
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Title |
An endoscopic approach to a snow leopard |
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Journal Article |
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1978 |
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Gastroenterology |
Abbreviated Journal |
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74 |
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6 |
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1348 |
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Animal; Bezoars; veterinary; Carnivora; Cats; Esophagoscopy; Male; browse; 370 |
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0016-5085 |
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Document Type: eng |
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SLN @ rana @ 47 |
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536 |
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