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Author Doster, A.R.; Armstrong, D.L.; Bargar, T.W. url 
  Title Seminoma and parathyroid adenoma in a snow leopard (Panthera unica) Type Journal Article
  Year 1989 Publication J Comp Pathol Abbreviated Journal  
  Volume 100 Issue (down) 4 Pages 475-480  
  Keywords Adenoma: pathology: veterinary; Animal; Carnivora; Dysgerminoma; pathology; veterinary; Male; Microscopy; Electron; neoplasms; Multiple Primary; Parathyroid; Testicular Neoplasms; adenoma; multiple; primary; Testicular; browse; 250  
  Abstract A seminoma and parathyroid adenoma were diagnosed in an aged snow leopard. The ultrastructural appearance of the seminoma was similar to that described in the dog and in man. The lack of significant amounts of rough endoplasmic reticulum, Golgi complexes and free ribosomes in the parathyroid adenoma suggested that it was non-functional. Parathyroid adenoma has not been previously described in a large wild feline.  
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  ISSN 0021-9975 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 142 Serial 244  
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Author Fix, A.S.; Riordan, D.P.; Hill, H.T.; Gill, M.A.; Evans, M.B.   
  Title Feline panleukopena virus and subsequent canine-distemper virus infection in two snow leopards (Panthera uncia) Type Journal Article
  Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal  
  Volume 20 Issue (down) 3 Pages 273-281  
  Keywords diagnosis; fecal; Fpv; leukemia; panleukopenia; panthera uncia; snow leopard; therapy; vaccination; veterinary; Virus; zoo  
  Abstract Two adult snow leopards (Panthera uncia), male and female, both with vaccinations current, became infected with feline panleukopenia virus (FPV) at the Blank Park Zoo, Des Moines, Iowa, in late 1988. Clinical signs included weakness, hemorrhagic feces, fever, seizures, and nasal discharge. Blood analysis revealed severe lymphopenia and mild anemia. A positive enzyme-linked immunosorbent assay (ELISA) test for FPV on fecal contents from the male leopard confirmed the diagnosis. In spite of intensive therapy, both animals died. Necropsy of the female, which survived for 1 wk after onset of signs, revealed intestinal crypt necrosis, pulmonary consolidation, necrotizing laryngitis, and diffuse lymphoid depletion. The male leopard, which lived 3 wk after onset of illness, had similar enteric and lymphoid lesions. In addition, there was a severe interstitial pneumonia, with syncytial cells containing eosinophilic intracytoplasmic inclusion bodies. Ultrastructural characteristics of these inclusions featured tubular structures consistent with a paramyxovirus. Although repeated virus isolation attempts from the affected lung were negative, polyclonal and monoclonal fluorescent antibody tests were strongly positive for canine distemper virus (CDV). Frozen paired sera from each leopard demonstrated very high acute and convalescing titers to FPV; both animals also seroconverted to CDV, with titers in the male leopard higher than those in the female. Additional tests for toxoplasmosis, feline infectious peritonitis, feline rhinotracheitis, feline calicivirus, feline leukemia, canine parainfluenza, and bovine respiratory syncytial virus were all negative. The neurologic signs present in these leopards remained unexplained, but may have been attributable to CDV infection. A feral cat trapped on zoo property had feces positive for FPV by ELISA. Although the specific contributions of FPV and CDV toward the development of this case are unknown, it is likely that initial FPV-induced immunosuppression allowed the subsequent development of CDV in these snow leopards. The likelihood that initial FPV infection came from feral cats underscores the importance of feral animal control on zoo premises.  
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  Notes Addresses:FIX AS, IOWA STATE UNIV SCI & TECHNOL,DEPT VET PATHOL,AMES,IA 50011IOWA STATE UNIV SCI & TECHNOL,VET DIAGNOST LAB,AMES,IA 50011BLANK PK ZOO,DES MOINES,IA 50315NORDEN LABS INC,LINCOLN,NE 68501NATL VET SERV LABS,AMES,IA 50010 Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Connective Phrase: English Approved no  
  Call Number SLN @ rana @ 147 Serial 277  
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Author Karesh, W.B.; Asterino, R. url 
  Title Mandibular osteomyelitis in a snow leopard (Panthera-uncia) with a review of osteomyelitis in other species and man Type Journal Article
  Year 1988 Publication Journal Of Zoo Animal Medicine Abbreviated Journal  
  Volume 19 Issue (down) 3 Pages 137-142  
  Keywords osteomyelitis; veterinary; medical; medicine; zoo; zoos; browse; 1540  
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  Notes Addresses:KARESH WB, WOODLAND PK ZOOL GARDENS,5500 PHINNEY AVE N,SEATTLE,WA 98103AVIAN & EXOT ANIM HOSP,HAWTHORNE,CA Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no  
  Call Number SLN @ rana @ 132 Serial 516  
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Author Ryan, J.A.; Roudebush, P.; Shores, J.   
  Title Laryngeal obstruction associated with cuterebrosis in a snow leopard (Felis-uncia) Type Journal Article
  Year 1990 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal  
  Volume 21 Issue (down) 3 Pages 346-352  
  Keywords Cuterebrosis; medecine; veterinary; medical; zoo; zoos; medicine; browse; 1480  
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  Notes Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no  
  Call Number SLN @ rana @ 160 Serial 837  
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Author Roth, T.L.; Armstrong, D.L.; Barrie, M.T.; Wildt, D.E. url 
  Title Seasonal effects on ovarian responsiveness to exogenous gonadotrophins and successful artificial insemination in the snow leopard (Uncia uncia) Type Journal Article
  Year 1997 Publication Reprod Fertil Dev Abbreviated Journal  
  Volume 9 Issue (down) 3 Pages 285-295  
  Keywords Animal; Carnivora; anatomy; histology; Blood; physiology; Estradiol; Female; Gonadotropins; administration; dosage; pharmacology; Chorionic; Equine; Human; Insemination; artificial; methods; veterinary; Laparoscopy; Male; Oocytes; cytology; Ovary; drug; effects; Ovulation; Induction; Pregnancy; Progesterone; Seasons; Support; Non-U.S.Gov't; browse; non; us; gov't; government; 400  
  Abstract Ovaries of the seasonally-breeding snow leopard (Uncia uncia) were examined to determine whether they were responsive to exogenous gonadotrophins throughout the year. The potential of laparoscopic artificial insemination (AI) also was assessed for producing offspring. During the non-breeding, pre-breeding, breeding and post-breeding seasons, females (n = 20) were treated with a standardized, dual- hormone regimen given intramuscularly (600 I.U. of equine chorionic gonadotrophin followed 80-84 h later with 300 I.U. of human chorionic gonadotrophin (hCG)). Laparoscopy was performed 45-50 h after administration of hCG, and all ovarian structures were described. Females with fresh corpora lutea (CL) were inseminated, and anovulatory females were subjected to follicular aspiration to examine oocyte quality. Snow leopards responded to exogenous gonadotrophins throughout the year. Mean number of total ovarian structures (distinct follicles mature in appearance plus CL) did not differ (P > or = 0.05) with season, but the proportion of CL: total ovarian structures was greater (P < 0.01) for the breeding season compared with all other seasons. The proportion of females ovulating was greater (P < 0.05) during the breeding and post-breeding seasons than during the pre-breeding and non- breeding seasons respectively. No Grade-1 quality oocytes were recovered from follicles of anovulatory females. Serum concentrations of oestradiol-17 beta appeared elevated in all females, and neither oestradiol-17 beta concentrations nor progesterone concentrations differed (P > or = 0.05) among seasons. Of 15 females artificially inseminated, the only one that was inseminated in the non-breeding season became pregnant and delivered a single cub. This is the first successful pregnancy resulting from AI in this endangered species.  
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  ISSN 1031-3613 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 325 Serial 830  
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Author Calle, P.P.; Colter, S.B.; Taylor, R.A.; Wright, A.M.   
  Title Extramedullary thoracolumbar fungal (scopulariopsis-brumptii) abscesses in 2 snow leopard (Panthera-uncia) littermates Type Journal Article
  Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal  
  Volume 20 Issue (down) 3 Pages 346-353  
  Keywords medecine; veterinary; medical; zoo; medicine; thoraclumbrar-fungal; browse; 1490  
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  Call Number SLN @ rana @ 131 Serial 207  
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Author Graham, L.H.; Goodrowe, K.L.; Raeside, J.I.; Liptrap, R.M. url 
  Title Non-invasive monitoring of ovarian function in several felid species by measurement of fecal estradiol-17-beta and progestins Type Journal Article
  Year 1995 Publication Zoo Biology Abbreviated Journal  
  Volume 14 Issue (down) 3 Pages 223-237  
  Keywords Artificial-Breeding-Program; captive-management; Estradiol-17beta; Pregnancy; Progesterone; Progestin; sexual-behavior; genetics; zoo; medicine; veterinary; snow-leopard; feces; fecal-analysis; snow leopard; artificial; breeding; program; captive; management; Estradiol; 17beta; sexual; behavior; browse; snow; leopard; fecal; analysis; 1390  
  Abstract An extraction and assay procedure to measure fecal estradiol-17-beta and progestin concentrations in several cat species was developed and validated for use for noninvasive monitoring of ovarian function. Fecal samples were collected over a range of 3-20 months from female tigers (three), lions (three), snow leopards (three), cheetahs (two), caracals (two), and domestic cats (five). Samples were extracted with 90% methanol, lipids removed with petroleum ether, and the estradiol and progestins in the methanol measured by radioimmunoassay (RIA). High Performance Liquid Chromatography (HPLC) fractionation and subsequent RIA of the fractions indicated that the estradiol-17-beta antiserum cross-reacted primarily with estradiol-17-beta in the feces of lions and tigers and was assumed to be specific for estradiol-17-beta in the feces of other species as well. However, there were several immunoreactive compounds, presumably progesterone metabolites, excreted in the feces which varied both quantitatively and qualitatively among species. The behavior of tigers, lions, cheetahs, and caracals was visually monitored during the collection period and frequency of sexual behaviors was positively correlated with increases in fecal estradiol in all species observed. The mean fecal estradiol-17-beta peaks were as follows: tigers, 128.0 +- 13.1; lions, 186.0 +- 14.8; snow leopards, 136.7 +- 15.9; cheetahs, 140.9 +- 9.0; caracals, 24.5 +- 4.0; and domestic cats 158.9 +- 19.3 ng/gm. Fecal progestin concentrations rose significantly (P lt 0,001) only after breeding or during pregnancy and were as follows: tigers, 5.6 +- 0.6; lions, 1.9 +- 0.1; cheetahs, 8.4 +- 1.1; and caracals, 2.4 +- 0.4 mu-g/gm. Fecal progestins were elevated for one-half to two-thirds of the gestation length during presumed pseudopregnancy but remained elevated throughout successful pregnancies. These results suggest that ovarian function can be monitored noninvasively in the family Felidae by the measurement of fecal estradiol-17-beta and progestin concentrations.  
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  Call Number SLN @ rana @ 279 Serial 345  
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Author McVittie, R. url 
  Title Nursing behavior of snow leopard cubs Type Journal Article
  Year 1978 Publication Applied-Animal-Ethology Abbreviated Journal  
  Volume 4 Issue (down) 2 Pages 159-168  
  Keywords suckling; behavior; veterinary; zoo; zoos; medical; browse; 1580  
  Abstract Reports that a preliminary project on nursing behavior in 3 young snow leopards revealed 2 phases in suckling pattern: nonnutritive and nutritive. The latter was distinguished by stereotypic rhythmical movements of the ears associated with swallowing. The cubs also demonstrated a teat preference, but the adaptive significance of such preferences and the accompanying agonistic behavior were unclear. (27 ref) (PsycINFO Database Record (c) 2000 APA, all rights reserved)(unassigned)  
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  Call Number SLN @ rana @ 37 Serial 669  
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Author Thorel, M.F.; Karoui, C.; Varnerot, A.; Fleury, C.; Vincent, V. url 
  Title Isolation of Mycobacterium bovis from baboons, leopards and a sea-lion Type Journal Article
  Year 1998 Publication Vet Res Abbreviated Journal  
  Volume 29 Issue (down) 2 Pages 207-212  
  Keywords Animal; Animals; zoo; Carnivora; microbiology; Case; Report; Cattle; Dna; Fingerprinting; Transposable; Elements; Disease; Outbreaks; veterinary; France; Genome; Bacterial; Germany; Male; Monkey; Diseases; diagnosis; epidemiology; Mycobacterium; Infections; bovis; classification; isolation; purification; Papio; Seals; browse; 440  
  Abstract This study reports on two series of cases of Mycobacterium bovis infection in zoo animals. The first was in a captive population of baboons (Papio hamadryas) and the second in a mixed group of wild mammals, including four leopards (Panthera uncia and Panthera pardus) and a sea-lion (Otaria byrona). The isolation and identification of strains of M. bovis confirmed the presence of M. bovis infections in both zoos. The epidemiological study using genetic markers such as the IS6110-based DNA fingerprinting system made it possible to differentiate between M. bovis strains. The M. bovis strains isolated from baboons were shown to contain a single IS6110 copy, as usually do cattle isolates, whereas the M. bovis strains isolated from the other exotic animals presented multiple copies. This finding suggests that the origin of the contamination for the baboons in zoo A could be related to cattle. The origin of the contamination for the leopards and sea-lion in zoo B is more difficult to determine. In conclusion, the authors suggest some recommendations for avoiding outbreaks of tuberculosis infections in zoos.  
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  ISSN 0928-4249 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 346 Serial 966  
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Author Jalanka, H.H. url 
  Title Medetomidine-induced and ketamine-induced immobilization of snow leopards (Panthera uncia) doses, evaluation and reversal by atipamezole Type Journal Article
  Year 1989 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal  
  Volume 20 Issue (down) 2 Pages 154-162  
  Keywords immobilization; drugs; dossage; doses; medetomidine; ketamine; veterinary; medical; medicine; zoo; zoos; atipamezole; browse; 1500  
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  Notes Addresses:JALANKA HH, HELSINKI ZOO,SF-00570 HELSINKI,FINLAND Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no  
  Call Number SLN @ rana @ 146 Serial 484  
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