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Author Schaffer, E.; Wiesner, H.; Von Hegel, G. url 
  Title Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) Type Journal Article
  Year 1988 Publication Tierarztl Prax Abbreviated Journal  
  Volume 16 Issue (up) 1 Pages 87-91  
  Keywords Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german  
  Abstract In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin.  
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  Series Volume Series Issue Edition  
  ISSN 0303-6286 ISBN Medium  
  Area Expedition Conference  
  Notes Document Type: German Approved no  
  Call Number SLN @ rana @ 112 Serial 851  
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Author Schmidt, R.E.; Eisenbrandt, D.L.; Hubbard, G.B. url 
  Title Tyzzer's disease in snow leopards Type Journal Article
  Year 1984 Publication J Comp Pathol Abbreviated Journal  
  Volume 94 Issue (up) 1 Pages 165-167  
  Keywords Animal; Animals; Newborn; zoo; Bacillus; Bacterial; Infections; pathology; veterinary; Carnivora; Liver; browse; 330  
  Abstract Tyzzer's disease was diagnosed histologically in 2 litters of newborn snow leopard kittens. The gross and histological lesions were similar to those reported in domestic cats and other animals. No signs of illness was noted in either of the snow leopard dams.  
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  ISSN 0021-9975 ISBN Medium  
  Area Expedition Conference  
  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 67 Serial 875  
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Author Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B. url 
  Title Feline papillomas and papillomaviruses Type Journal Article
  Year 2000 Publication Vet Pathol Abbreviated Journal  
  Volume 37 Issue (up) 1 Pages 1-10  
  Keywords Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120  
  Abstract Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2).  
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  ISSN 0300-9858 ISBN Medium  
  Area Expedition Conference  
  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 385 Serial 948  
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Author Desch, C. url 
  Title A new species of hair follicle mite (Acari: Demodecidae) from the snow leopard, Panthera uncia (Schreber, 1775) (Felidae) Type Journal Article
  Year 1993 Publication International Journal of Acarology Abbreviated Journal  
  Volume 19 Issue (up) 1 Pages 63-67  
  Keywords snow-leopard; mites; mite; zoo; zoos; veterinary; medical; medicine; snow leopard; browse; 1440  
  Abstract A new species of Demodex is described, in all instars, from the rare and endangered snow leopard, Panthera uncia. This represents only the second demodecid from the family Felidae and the first from a wild cat species. The mite specimens were taken from juvenile hosts raised in captivity. Demodex uncii sp. nov. closely resembles Demodex cati.  
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  Notes Document Type: English Approved no  
  Call Number SLN @ rana @ 190 Serial 236  
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Author Kolmstetter, C.; Munson, L.; Ramsay, E.C. url 
  Title Degenerative spinal disease in large felids Type Journal Article
  Year 2000 Publication J Zoo Wildl Med Abbreviated Journal  
  Volume 31 Issue (up) 1 Pages 15-19  
  Keywords Age-Factors; Animal; Animals; zoo; Autopsy; veterinary; Carnivora; Female; Lions; Male; Age; factor; browse; 110  
  Abstract Degenerative spinal disorders, including intervertebral disc disease and spondylosis, seldom occur in domestic cats. In contrast, a retrospective study of 13 lions (Panthera leo), 16 tigers (Panthera tigris), 4 leopards (Panthera pardis), 1 snow leopard (Panthera uncia), and 3 jaguars (Panthera onca) from the Knoxville Zoo that died or were euthanatized from 1976 to 1996 indicated that degenerative spinal disease is an important problem in large nondomestic felids. The medical record, radiographic data, and the necropsy report of each animal were examined for evidence of intervertebral disc disease or spondylosis. Eight (three lions, four tigers, and one leopard) animals were diagnosed with degenerative spinal disease. Clinical signs included progressively decreased activity, moderate to severe rear limb muscle atrophy, chronic intermittent rear limb paresis, and ataxia. The age at onset of clinical signs was 10-19 yr (median = 18 yr). Radiographic evaluation of the spinal column was useful in assessing the severity of spinal lesions, and results were correlated with necropsy findings. Lesions were frequently multifocal, included intervertebral disc mineralization or herniation with collapsed intervertebral disc spaces, and were most common in the lumbar area but also involved cervical and thoracic vertebrae. Marked spondylosis was present in the cats with intervertebral disc disease, presumably subsequent to vertebral instability. Six of the animals' spinal cords were examined histologically, and five had acute or chronic damage to the spinal cord secondary to disc protrusion. Spinal disease should be suspected in geriatric large felids with decreased appetite or activity. Radiographic evaluation of the spinal column is the most useful method to assess the type and severity of spinal lesions.  
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  ISSN 1042-7260 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 384 Serial 545  
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Author Kazensky, C.A.; Munson, L.; Seal, U.S.   
  Title The effects of melengestrol acetate on the ovaries of captive wild felids Type Journal Article
  Year 1998 Publication Journal-of-Zoo-and-Wildlife-Medicine Abbreviated Journal  
  Volume 29 Issue (up) 1 Pages 1-5  
  Keywords Mga; zoo; felids; contraception; Melengestrol-acetate; ovaries; snow-leopard; Panthera-uncia; snow leopard; browse; uncia; panthera; melengestrol; acetate; 1260; effects; study; ovarian; Ovary; captive; wild; wild felid; Wild-Felid; species; Follicle; Cats; cat; recent; Ovulation; doses; Dose; action; Progestin; Disease; veterinary  
  Abstract Melengestrol acetate (MGA) is the most widely used contraceptive in zoo felids, but the mechanism of contraception and the pathologic effects have not been investigated. For this study, the effects of MGA on folliculogenesis were assessed, and the association of MGA with ovarian lesions was evaluated. Comparisons were made among the histopathologic findings in the ovaries from 88 captive wild felids (representing 15 species) divided into three groups: 37 currently contracepted with MGA, eight previously exposed to MGA, and 43 never contracepted. Ninety-one percent of the felids evaluated had tertiary follicles, and no differences were noted between contracepted and uncontracepted cats. Some MGA-contracepted cats also had corpora lutea indicating recent ovulation. These results indicate that folliculogenesis is not suppressed by current doses of MGA and ovulation occurred in some cats. Therefore, the contraceptive actions of MGA do not occur by suppressing folliculogenesis, and MGA-contracepted felids likely have endogenous estrogens that may confound progestin effects on the uterus. Cystic rete ovarii was the most common pathologic finding, but they were not more prevalent in MGA-contracepted cats. These findings indicate that MGA is not associated with ovarian disease, including ovarian cancer, in contrast to the uterine lesions noted in MGA-treated cats.  
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  Notes Document Type: English. Affiliation: Taylor Veterinary Hospital, Turlock , California 95382, USA Approved no  
  Call Number SLN @ rana @ 348 Serial 527  
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Author Paul, H.A.; Bargar, W.L.; Leininger, R. url 
  Title Total hip replacement in a snow leopard Type Journal Article
  Year 1985 Publication J Am Vet Med Assoc Abbreviated Journal  
  Volume 187 Issue (up) 11 Pages 1262-1263  
  Keywords Animal; Carnivora; surgery; Case; Report; Hip; Dislocation; veterinary; Prosthesis; Male; browse; 310  
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  Series Volume Series Issue Edition  
  ISSN 0003-1488 ISBN Medium  
  Area Expedition Conference  
  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 82 Serial 760  
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Author Chandra, S.; Laughlin, D.C. url 
  Title Virus-like particles in cystic mammary adenoma of a snow leopard Type Journal Article
  Year 1975 Publication Cancer Res Abbreviated Journal  
  Volume 35 Issue (up) 11 Pt 1 Pages 3069-3074  
  Keywords Adenoma pathology veterinary; Animal; Animals; zoo; Carnivora; Cytoplasmic Granules; Endoplasmic Reticulum: ultrastructure; Inclusion Bodies; Mammae: pathology; Neoplasms: pathology: veterinary; neoplasms; pathology; mammae; inclusion; bodies; ultrastructure; reticulum; endoplasmic; granules; cytoplasmic; adenoma; veterinary; browse; 380  
  Abstract Virus-like particles were observed in the giant cells of a mammary adenoma of a snow leopard kept in captivity. Particles that measured 115 to 125 nm in diameter budded from the lamella of endoplasmic reticulum and were studded on their inner surfaces with dense granules (approximately 12 nm) that gave them their unique ultrastructural morphology. Such particles were not observed extracellularly. Type B or type C particles were not seen in the tumor tissue.  
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  ISSN 0008-5472 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 27 Serial 212  
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Author Lutz, H.; Hofmann-Lehmann, R.; Fehr, D.; Leutenegger, C.; Hartmann, M.; Ossent, P.; Grob, M.; Elgizoli, M.; Weilenmann, P. url 
  Title Liberation of the wilderness of wild felids bred under human custody: Danger of release of viral infections Type Journal Article
  Year 1996 Publication Schweizer Archiv fuer Tierheilkunde Abbreviated Journal  
  Volume 138 Issue (up) 12 Pages 579-585  
  Keywords endangered-species; European-Wild-Cat; Fiv; Fpv; Host; Human-Custody; infection; Pathogen; Reintroduction-Projects; Relocation-Projects; survival; Tibet; Veterinary-Medicine; Viral-Disease; Viral-Infection; Wild-Felid; Wild-Felid-Breeding; Wilderness-Liberation; Wildlife-Management; browse; endangered; species; european; wild; cat; Human; custody; reintroduction; project; relocation; veterinary; medicine; Viral; Disease; wild felid; breeding; wilderness; liberation; management; 690  
  Abstract There are several felidae amongst the numerous endangered species. Means of aiding survival are the reintroduction to the wild of animals bred under the auspices of man and their relocation from densely populated to thinly populated areas. It is unlikely that the dangers of such reintroduction or relocation projects have been examined sufficiently in respect to the risks of virus infections confronting individuals kept in zoos or similar situations. This report presents infections may be expected to occur when relo- three examples to illustrate that accidental virus cating and reintroducing wild cats. The first example is the reintroduction of captive snow leopards. Zoo bred snow leopards may be infected with FIV, a virus infection that is highly unlikely to occur in the original hirnalayan highlands of Tibet and China. A second example is of several cases of FIP that occured in European wild cats bred in groups in captivity. The third example mentioned is the relocation of hons from East Africa where all the commonly known feline viruses are wide-spread to the Etosha National Park. In the latter, virus infections such as FIV, FCV and FPV do not occur. The indiscriminate relocation and reintroduction of the wild cats mentioned here harbours a potential of undesirable consequences.  
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  Notes Document Type: German Approved no  
  Call Number SLN @ rana @ 287 Serial 629  
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Author McVittie, R. url 
  Title Nursing behavior of snow leopard cubs Type Journal Article
  Year 1978 Publication Applied-Animal-Ethology Abbreviated Journal  
  Volume 4 Issue (up) 2 Pages 159-168  
  Keywords suckling; behavior; veterinary; zoo; zoos; medical; browse; 1580  
  Abstract Reports that a preliminary project on nursing behavior in 3 young snow leopards revealed 2 phases in suckling pattern: nonnutritive and nutritive. The latter was distinguished by stereotypic rhythmical movements of the ears associated with swallowing. The cubs also demonstrated a teat preference, but the adaptive significance of such preferences and the accompanying agonistic behavior were unclear. (27 ref) (PsycINFO Database Record (c) 2000 APA, all rights reserved)(unassigned)  
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  Area Expedition Conference  
  Notes Document Type: English Approved no  
  Call Number SLN @ rana @ 37 Serial 669  
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