Abstract: A description of the Kyzylsu, Miraki, and Markakol nature reserves is given and includes as follows: data of establishment, location, physic and geographic description, types of soils, climate, vegetation, altitude zones, and fauna. In the Kyzylsu nature reserve there are 28 mammal species; in Miraki 23, and in Mirkakol 39. Snow leopard can be found in all the three nature reserves.

Abstract: It provides geobotanic and zoogeographic description of vertical landscape zoning. Particularly, in alpine meadows and meadow steppes and partially zone of mountain plateau (“syrt”) of highland, the common species are argali (Ovis ammon poloi), ibex (Capra sibirica sakeen), snow leopard (Felis uncia), Tien Shan bear (Ursus arctos leuconyx), and red pica; very numerous are marmots and vole (Microtus gregalis). The bird fauna includes Himalayan snow-cock (Tetraogallus himalayensis), Alpine chough (Pyrrhocorax graculus), chough (P. pyrrhocorax), horned lark (Eremophila alpestris), rosefinch species. There are many waterfowl birds on the lakes. There are many Central Asian, particularly Tibetan species among the animals inhabiting highlands of the Tien Shan.

Abstract: 224 animal species, including two relict and 20 endemic, are registered in the Besh Aral nature reserve (Kyrgyzstan). This nature reserve is inhabited by rare and endangered animal and bird species (e.g. Menzbier's marmot, snow leopard, Tien Shan brown bear, manul, Turkistan lynx, saker falcon, bearded vulture, golden eagle, Himalayan griffon, and others) included in the Red Data Books of Kyrgyzstan, former USSR, and Led List of IUCN.

Abstract: Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2).

Abstract: Tyzzer's disease was diagnosed histologically in 2 litters of newborn snow leopard kittens. The gross and histological lesions were similar to those reported in domestic cats and other animals. No signs of illness was noted in either of the snow leopard dams.