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Author Chandra, S.; Laughlin, D.C.
Title Virus-like particles in cystic mammary adenoma of a snow leopard Type Journal Article
Year 1975 Publication Cancer Res Abbreviated Journal
Volume 35 Issue 11 Pt 1 Pages 3069-3074
Keywords Adenoma pathology veterinary; Animal; Animals; zoo; Carnivora; Cytoplasmic Granules; Endoplasmic Reticulum: ultrastructure; Inclusion Bodies; Mammae: pathology; Neoplasms: pathology: veterinary; neoplasms; pathology; mammae; inclusion; bodies; ultrastructure; reticulum; endoplasmic; granules; cytoplasmic; adenoma; veterinary; browse; 380
Abstract Virus-like particles were observed in the giant cells of a mammary adenoma of a snow leopard kept in captivity. Particles that measured 115 to 125 nm in diameter budded from the lamella of endoplasmic reticulum and were studded on their inner surfaces with dense granules (approximately 12 nm) that gave them their unique ultrastructural morphology. Such particles were not observed extracellularly. Type B or type C particles were not seen in the tumor tissue.
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ISSN (up) 0008-5472 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 27 Serial 212
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Author Kleinman, M.S.; Garman, R.H.
Title An endoscopic approach to a snow leopard Type Journal Article
Year 1978 Publication Gastroenterology Abbreviated Journal
Volume 74 Issue 6 Pages 1348
Keywords Animal; Bezoars; veterinary; Carnivora; Cats; Esophagoscopy; Male; browse; 370
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ISSN (up) 0016-5085 ISBN Medium
Area Expedition Conference
Notes Document Type: eng Approved no
Call Number SLN @ rana @ 47 Serial 536
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Author Doster, A.R.; Armstrong, D.L.; Bargar, T.W.
Title Seminoma and parathyroid adenoma in a snow leopard (Panthera unica) Type Journal Article
Year 1989 Publication J Comp Pathol Abbreviated Journal
Volume 100 Issue 4 Pages 475-480
Keywords Adenoma: pathology: veterinary; Animal; Carnivora; Dysgerminoma; pathology; veterinary; Male; Microscopy; Electron; neoplasms; Multiple Primary; Parathyroid; Testicular Neoplasms; adenoma; multiple; primary; Testicular; browse; 250
Abstract A seminoma and parathyroid adenoma were diagnosed in an aged snow leopard. The ultrastructural appearance of the seminoma was similar to that described in the dog and in man. The lack of significant amounts of rough endoplasmic reticulum, Golgi complexes and free ribosomes in the parathyroid adenoma suggested that it was non-functional. Parathyroid adenoma has not been previously described in a large wild feline.
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ISSN (up) 0021-9975 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 142 Serial 244
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Author Schmidt, R.E.; Eisenbrandt, D.L.; Hubbard, G.B.
Title Tyzzer's disease in snow leopards Type Journal Article
Year 1984 Publication J Comp Pathol Abbreviated Journal
Volume 94 Issue 1 Pages 165-167
Keywords Animal; Animals; Newborn; zoo; Bacillus; Bacterial; Infections; pathology; veterinary; Carnivora; Liver; browse; 330
Abstract Tyzzer's disease was diagnosed histologically in 2 litters of newborn snow leopard kittens. The gross and histological lesions were similar to those reported in domestic cats and other animals. No signs of illness was noted in either of the snow leopard dams.
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ISSN (up) 0021-9975 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 67 Serial 875
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Author Chaudhuri, S.; Mukherjee, S.K.; Chatterjee, A.; Ganguli, J.L.
Title Isolation of P multocida F-3, 4 from a stillborn snow leopard Type Journal Article
Year 1992 Publication Vet Rec Abbreviated Journal
Volume 130 Issue 2 Pages 36
Keywords Animal; Bacteremia; Blood; browse; Carnivora; Death; Diseases; Female; Fetal; Infections; isolation; microbiology; multocida; Pasteurella; Pregnancy; purification; veterinary
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ISSN (up) 0042-4900 ISBN Medium
Area Expedition Conference
Notes Document Type: eng Approved no
Call Number SLN @ rana @ 187 Serial 214
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Author Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B.
Title Feline papillomas and papillomaviruses Type Journal Article
Year 2000 Publication Vet Pathol Abbreviated Journal
Volume 37 Issue 1 Pages 1-10
Keywords Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120
Abstract Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2).
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ISSN (up) 0300-9858 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 385 Serial 948
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Author Munson, L.; Worley, M.B.
Title Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks Type Journal Article
Year 1991 Publication Vet Pathol Abbreviated Journal
Volume 28 Issue 1 Pages 37-45
Keywords Cirrhosis; epidemiology; Hemosiderosis; Hepadnaviridae; Hepatic; Hepatitis; pathology; Veno-Occlusive; veterinary; zoo
Abstract Livers from 54 snow leopards, 4 days to 23 years old, that had died in 23 US zoos, were evaluated histopathologically to determine if the hepatic fibrosis, which has been noted to be prevalent in this species, was due to chronic active hepatitis from hepadnaviral infection, Ito cell proliferation, or hemosiderosis. Forty-two of 54 snow leopards had subintimal vascular fibrosis with partial or total occlusion of central and sublobular veins (veno-occlusive disease) of unknown origin. All 21 leopards older than 5 years were affected. Four leopards had chronic active hepatitis, and 12 leopards had cholangiohepatitis; but these lesions were not connected anatomically to central and sublobular venous fibrosis. Hepatocellular and Kupffer cell siderosis and Ito cell proliferation were prevalent and often coexisted with perisinusoidal, central, and sublobular venous fibrosis; but fibrosis was present in leopards without siderosis or Ito cell proliferation. The pattern and prevalence of veno-occlusive disease in these leopards was similar to that reported in captive cheetah (Acinonyx jubatus), suggesting that a common extrinsic factor may cause the majority of hepatic disease in these large felid animals in captivity.
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ISSN (up) 0300-9858 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 173 Serial 706
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Author Gosselin, S.J.; Loudy, D.L.; Tarr, M.J.; Balistreri, W.F.; Setchell, K.D.; Johnston, J.O.; Kramer, L.W.; Dresser, B.L.
Title Veno-occlusive disease of the liver in captive cheetah Type Journal Article
Year 1988 Publication Vet Pathol Abbreviated Journal
Volume 25 Issue 1 Pages 48-57
Keywords Animal; Feed; analysis; Carnivora; Cheetahs; Female; Hepatic; Veno; Occlusive; Disease; pathology; veterinary; Histocytochemistry; Liver; ultrastructure; Male; Microscopy; Electron; Support; Non-U.S.Gov't; Vitamin A; browse; non; us; gov't; government; 280
Abstract Liver tissues from 126 captive cheetah were evaluated by light microscopy and histochemistry; eight animals were evaluated by electron microscopy. The main hepatic lesion, a vascular lesion resembling veno- occlusive disease (VOD) of the liver and characterized by subendothelial fibrosis and proliferation of smooth muscle-like cells in the central veins, was seen in 60% of the sexually mature cheetah. Although this hepatic vascular lesion was seen in cheetah as young as 1 year of age, the most severe lesions, usually associated with liver failure, were found in cheetah between the ages of 6 and 11. There was no sex predisposition, and in approximately 40% of the VOD cases, liver disease was not suspected clinically or at necropsy. VOD was found in other felidae, especially in the snow leopard. High levels of vitamin A in livers, as well as in diets of the cheetah, could be a contributing factor in the development of VOD in some groups of cheetah.
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ISSN (up) 0300-9858 ISBN Medium
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Notes Document Type: Eng Approved no
Call Number SLN @ rana @ 127 Serial 339
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Author Schaffer, E.; Wiesner, H.; Von Hegel, G.
Title Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) Type Journal Article
Year 1988 Publication Tierarztl Prax Abbreviated Journal
Volume 16 Issue 1 Pages 87-91
Keywords Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german
Abstract In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin.
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ISSN (up) 0303-6286 ISBN Medium
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Notes Document Type: German Approved no
Call Number SLN @ rana @ 112 Serial 851
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Author Thorel, M.F.; Karoui, C.; Varnerot, A.; Fleury, C.; Vincent, V.
Title Isolation of Mycobacterium bovis from baboons, leopards and a sea-lion Type Journal Article
Year 1998 Publication Vet Res Abbreviated Journal
Volume 29 Issue 2 Pages 207-212
Keywords Animal; Animals; zoo; Carnivora; microbiology; Case; Report; Cattle; Dna; Fingerprinting; Transposable; Elements; Disease; Outbreaks; veterinary; France; Genome; Bacterial; Germany; Male; Monkey; Diseases; diagnosis; epidemiology; Mycobacterium; Infections; bovis; classification; isolation; purification; Papio; Seals; browse; 440
Abstract This study reports on two series of cases of Mycobacterium bovis infection in zoo animals. The first was in a captive population of baboons (Papio hamadryas) and the second in a mixed group of wild mammals, including four leopards (Panthera uncia and Panthera pardus) and a sea-lion (Otaria byrona). The isolation and identification of strains of M. bovis confirmed the presence of M. bovis infections in both zoos. The epidemiological study using genetic markers such as the IS6110-based DNA fingerprinting system made it possible to differentiate between M. bovis strains. The M. bovis strains isolated from baboons were shown to contain a single IS6110 copy, as usually do cattle isolates, whereas the M. bovis strains isolated from the other exotic animals presented multiple copies. This finding suggests that the origin of the contamination for the baboons in zoo A could be related to cattle. The origin of the contamination for the leopards and sea-lion in zoo B is more difficult to determine. In conclusion, the authors suggest some recommendations for avoiding outbreaks of tuberculosis infections in zoos.
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ISSN (up) 0928-4249 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 346 Serial 966
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