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Author Nikolaevskiy A.G.
Title The Kyrgyz state nature park “Ala-Archa”. People's park of the Uzbek SSR Type Miscellaneous
Year 1985 Publication Abbreviated Journal
Volume Issue Pages 89-92
Keywords Kyrgyzsatn; Ala-Archa national park; location; climate; soils; relief; plants; Animals; mammals; snow leopard.; 7750
Abstract It provides general information about the Kyrgyz state nature park ®Ala-Archa", its physico-geographical features, relief, landscape zoning, and description of flora and fauna. Snow leopard, Tien-Shan brown bear, ibex (more than 300 animals), porcupine, stone marten, ermine, and marmot, etc. are mentioned as the most interesting animals.
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Notes 1950Journal Title: National parks. Approved no
Call Number SLN @ rana @ 753 Serial 720
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Author Potapov R.
Title On the top of ridges Type Miscellaneous
Year 1986 Publication Abbreviated Journal
Volume Issue Pages 146-162
Keywords Tajikistan; Pamir; Animals; snow leopard; ibex.; 7970; Russian
Abstract In a popular form, it says about wildlife of Pamir, unique animal kingdom of highlands. The author describes his personal encounter with snow leopard following a herd of ibex and thinks of peculiarities of this large predator and reasons for hunting it.
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Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title Tiger gully. Unknown world.
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Notes Full text available in Russian Approved no
Call Number SLN @ rana @ 775 Serial 785
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Author Yazan Yu.P.
Title The Almaty state nature reserve Type Miscellaneous
Year 1980 Publication Abbreviated Journal
Volume Issue Pages 162-164
Keywords Kazakhstan; Almaty nature reserve; establishment; climate; physiographic factors; plants; Animals; insects; reptiles; birds; mammals; snow leopard.; 8590; Russian
Abstract History of the Alma-Ata nature reserve establishment, its location physical and geographic data, climate, and vegetation zones are described. Fauna of the protected area is represented by 64 mammal species, and about 200 bird species. Briefly described are behavioural patterns of roe deer, moral, wild boar, Siberian ibex, snow leopard, lynx, brown bear, and marten, and other mammals of the mountainous area.
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Notes Full text available in RussianJournal Title: Nature reserves of the USSR. Approved no
Call Number SLN @ rana @ 836 Serial 1058
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Author Zhiryakov V.A.
Title The influence of large predators on wild mammal populations in the Almaty nature reserve Type Miscellaneous
Year 1979 Publication Abbreviated Journal
Volume Issue Pages 37-39
Keywords Kazakhstan; Almaty nature reserve; Animals; predators; snow leopard; wolf; preys.; 8760; Russian
Abstract There are following large predators in the Almaty nature reserve: wolf (5-6), snow leopard (single occasions), Turkistan lynx (single occasions), and Tien Shan brown bear (15-20). The share of wild mammals (roe-deer, ibex, wild boar, argali, gazelle, moral, and badger) being eaten by predators is 18.2 percent, about 60 percent of the entire prey falling to the share of wolf.
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Notes Full text available in RussianJournal Title: Ecologic fundamentals of protection and sustainable use of predatory mammals. Approved no
Call Number SLN @ rana @ 853 Serial 1083
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Author Zhou, S.
Title On “uncia uncia” and “meng ji” in Shan Hai Jin Type Miscellaneous
Year 1991 Publication Abbreviated Journal
Volume 13 Issue 2 Pages 84-87
Keywords Animal; area; areas; China; Chinese; description; environment; fur; habitat; habitats; historical; meng ji; mountain; mountains; native; river; uncia; Uncia-uncia; Uncia uncia
Abstract Meng ji is described in Shan Hui Jin (Classic of Mountains and Rivers) as a leopard-like animal adept in hiding with white fur and a patterned forehead. This article makes a comparison between “meng ji” and “uncia uncia” in terms of their shapes, fur colors, natural environments of habitats, habits, characteristics and native areas, and comes to the conclusion that “meng ji” is what we call “uncia uncia” nowadays. The description of “meng ji” in Shan Hui Jin should be the first record of Uncia uncia in the world.
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Notes Full text available in ChineseJournal Title: China Historical Materials of Science and Technology Approved no
Call Number SLN @ rana @ 869 Serial 1089
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Author Vipin, Golla, T. R., Sharma, V., Kumar, B. K., Gaur, A.
Title Kleptoparasitic interaction between Snow Leopard Panthera uncia and Red Fox Vulpes vulpes suggested by circumstantial evidence in Pin Valley National Park, India Type Journal Article
Year 2022 Publication Journal of Threatened Taxa Abbreviated Journal
Volume 14 Issue 10 Pages 21928-21935
Keywords Animal interaction, carnivore, mammals, prey, Trans-Himalaya.
Abstract In the present study, we describe an interspecific kleptoparasitic interaction between two sympatric mammalian carnivores in the high altitudinal Trans-Himalaya region of Himachal Pradesh, India. The study was based on the inferences drawn from the circumstantial evidence (direct and indirect) noticed in the study area in Pin Valley National Park. The inferences from the analysis of the evidence suggested the interaction between a Snow Leopard Panthera uncia, a Red Fox Vulpes vulpes, and a donkey. The arrangement of evidence in a sequential manner suggested that a donkey was killed by a Snow Leopard and a Red Fox stole the food from the carrion of the Snow Leopard’s prey. The Red Fox was killed by the Snow Leopard, which was caught while stealing. The present study represents an example of kleptoparasitic interaction between the Snow Leopard and the Red Fox. This study also proves that such interactions may cost the life of a kleptoparasite and supports the retaliation behaviour of Snow Leopards.
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Notes Approved no
Call Number SLN @ rakhee @ Serial 1702
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Author Johansson, O., Kachel, S., Weckworth, B.
Title Guidelines for Telemetry Studies on Snow Leopards Type Journal Article
Year 2022 Publication Animals Abbreviated Journal
Volume 12 Issue 1663 Pages 1-12
Keywords animal welfare; capture; collar; felid; GPS; immobilization; Panthera uncia; trapping
Abstract Animal-borne tracking devices have generated a wealth of new knowledge, allowing us to better understand, manage and conserve species. Fitting such tracking devices requires that animals are captured and often chemically immobilized. Such procedures cause stress and involve the risk of injuries and loss of life even in healthy individuals. For telemetry studies to be justifiable, it is vital that capture operations are planned and executed in an efficient and ethical way. Project objectives must be clearly articulated to address well-defined knowledge gaps, and studies designed to maximize the probability of achieving those goals. We provide guidelines for how to plan, design, and implement telemetry studies with a special emphasis on snow leopards that are typically captured using foot snares. We also describe the necessary steps to ensure that captures are conducted safely, and with minimal stress to animals.
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Notes Approved no
Call Number SLN @ rakhee @ Serial 1712
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Author Moheb, Z., Sahel, K., Fazli, M., Hakimi, M., Ismaily, S.
Title Snow Leopard Intrusions into Livestock Corrals in Badakhshan, Afghanistan: Challenges and Solutions Type Journal Article
Year 2023 Publication Snow Leopard Reports Abbreviated Journal
Volume Issue Pages 1-5
Keywords Panthera uncia, corral intrusion, livestock predation, occurrence record, problematic animal
Abstract Snow leopards (Panthera uncia) frequently prey on livestock throughout their range, posing a potential threat to human livelihoods and endangering the predator’s own survival. In this study, we document seven incidents of snow leopards intruding into livestock corrals and engaging in surplus killing in three districts of Badakhshan, Afghanistan. Six of the predation incidents were attributed to a single individual, occurring in five locations of Wakhan District and eventually in Yumgan District, where the captured animal was relocated. The remaining predation incident occurred in Keran-wa Munjan District, marking the first recorded evidence of snow leopards in this area. In all but one of the incidents, the predator was trapped in the corral it intruded and safely released back to the wild with the support of the National Environmental Protection Agency (NEPA) and Wildlife Conservation Society (WCS) team in Afghanistan. Local communities have been supportive in releasing the snow leopard despite losses of over 50 livestock. To mitigate negative interactions between snow leopards and livestock, conservation efforts should focus on conserving prey species, implementing predator- proof measures for livestock corrals, and utilizing collar tracking when a trapped snow leopard is found in a corral. Unfortunately, when an individual repeatedly enters livestock corrals and continues killing livestock, capture and relocation to captivity often become the only viable option to address the problem and ensure the animal’s safety from retaliatory action by affected herders.
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Notes Approved no
Call Number SLN @ rakhee @ Serial 1728
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Author Ale, S.; Brown, J.
Title The contingencies of group size and vigilance Type Miscellaneous
Year 2007 Publication Evolutionary Ecology Research, Abbreviated Journal
Volume 9 Issue Pages 1263-1276
Keywords attraction effect,contingency,dilution effect,fitness,group-size effect,many-eyes effect,predation risk,vigilance behaviour; predation; decline; potential; predators; predator; feeding; Animals; Animal; use; food; effects; Relationship; behaviour; methods; game; Interactions; interaction; factor; value; Energy
Abstract Background: Predation risk declines non-linearly with one's own vigilance and the vigilance of others in the group (the 'many-eyes' effect). Furthermore, as group size increases, the individual's risk of predation may decline through dilution with more potential victims, but may increase if larger groups attract more predators. These are known, respectively, as the dilution effect and the attraction effect.

Assumptions: Feeding animals use vigilance to trade-off food and safety. Net feeding rate declines linearly with vigilance.

Question: How do the many-eyes, dilution, and attraction effects interact to influence the relationship between group size and vigilance behaviour?

Mathematical methods: We use game theory and the fitness-generating function to determine the ESS level of vigilance of an individual within a group.

Predictions: Vigilance decreases with group size as a consequence of the many-eyes and dilution effects but increases with group size as a consequence of the attraction effect, when they act independent of each other. Their synergetic effects on vigilance depend upon the relative strengths of each and their interactions. Regardless, the influence of other factors on vigilance – such as encounter rate with predators, predator lethality, marginal value of energy, and value of vigilance – decline with group size.
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Notes Approved no
Call Number SLN @ rana @ 886 Serial 53
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Author Esipov V.M.
Title The status and perspective protection and rehabilitation of natural ecosystems in the Chatkal state biosphere nature reserve under the State Committee for Agriculture and Industry of the USSR Type Miscellaneous
Year 1986 Publication Abbreviated Journal
Volume Issue Pages 15-17
Keywords Uzbekistan; Chatkal nature reserve; establishment; conservation regime; Animals; snow leopard.; 6580; Russian
Abstract The area of the Chatkal nature reserve reduced as part of its territory (a land plot in the Shavasay river basin) was assigned to a military game preserve. As regime of protection worsened, number of animals such as Menzbier's marmot, snow leopard, ibex, snow cock, and black stork began to reduce.
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Notes Full text available in RussianJournal Title: Geographical problems of wildlife protection development. Approved no
Call Number SLN @ rana @ 636 Serial 265
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Author Esipov V.M.
Title The nature reserve in the spurs of Tien Shan Type Miscellaneous
Year 1978 Publication Abbreviated Journal
Volume Vol.8. Issue Pages 8
Keywords Uzbekistan; Chatkal nature reserve; location; Animals; snow leopard.; 6560; Russian
Abstract The Chatkal state mountain forest nature reserve is located in western spurs of the Chatkal ridge. The permanent inhabitants of the nature reserve are ibex, wild boar, roe-deer, bear, badger, porcupine, stone marten, fox, ermine, Menzbier's marmot, and relict suslik (gopher), and bird species such as gray partridge, snow-cock, black vulture, griffon vulture, etc. Under special protection are rare animal and bird species such as snow leopard, Menzbier's marmot, bearded vulture, golden eagle, etc.
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Notes Full text available in RussianJournal Title: Journal `Soviet Uzbekistan Today' Approved no
Call Number SLN @ rana @ 634 Serial 263
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Author Chumakova A.V.
Title The Kyzylsu, Miraki, and Markakol nature reserves Type Miscellaneous
Year 1980 Publication Abbreviated Journal
Volume Issue Pages 153-155
Keywords Central Asia; nature reserves; Kysylsu nature reserve; Miraki nature reserve; Markakol nature reserve; establishment; soil; climate; physiographic factors; researching; plants; Animals; snow leopard.; 6470; Russian
Abstract A description of the Kyzylsu, Miraki, and Markakol nature reserves is given and includes as follows: data of establishment, location, physic and geographic description, types of soils, climate, vegetation, altitude zones, and fauna. In the Kyzylsu nature reserve there are 28 mammal species; in Miraki 23, and in Mirkakol 39. Snow leopard can be found in all the three nature reserves.
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Notes Full text available in RussianJournal Title: Nature reserves of the USSR. Approved no
Call Number SLN @ rana @ 625 Serial 220
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Author Chichikin Yu.N., Y.A.I.
Title Issyk Kul nature reserve Type Miscellaneous
Year 1969 Publication Abbreviated Journal
Volume Issue Pages 475-480
Keywords Kyrgyzstan; Issyk Kul nature reserve; Jety Oguz site; establishment; climate; physiographic factors; plants; Animals; snow leopard.; 6460; Russian
Abstract A description of the Issyk Kul nature reserve (Kyrgyzstan) is given and includes as follows: data of establishment, location, physic and geographic description, climate, flora and fauna. Snow leopard inhabited in Jety Oguz site of the nature reserve.
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Notes Full text available in RussianJournal Title: Protected areas of Soviet Union. Approved no
Call Number SLN @ rana @ 624 Serial 219
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Author Golub O.N.
Title The Ramit nature reserve and its problems Type Miscellaneous
Year 1981 Publication Abbreviated Journal
Volume Issue Pages 60-61
Keywords Tajikistan; Ramit nature reserve; Animals; snow leopard; ibex; number; threats.; 6770; Russian
Abstract The following Red Data Book species inhabit the Ramit nature reserve: snow leopard, bear, lynx, otter, Bukhara deer, etc. Its population is indicated to be closely related to number of ibex (150 animals). The latter is subject to heavy anthropogenic pressure when migrating outside the nature reserve in winter.
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Notes Full text available in RussianJournal Title: The status and perspectives of wildlife protection in the USSR. Approved no
Call Number SLN @ rana @ 655 Serial 337
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Author Gvozdetskiy N.A.
Title Altitudal landscape zones Type Miscellaneous
Year 1970 Publication Abbreviated Journal
Volume Issue Pages 142-151
Keywords Central Asia; geobotany; zoogeography; mountain zones; Animals; snow leopard.; 6840; Russian
Abstract It provides geobotanic and zoogeographic description of vertical landscape zoning. Particularly, in alpine meadows and meadow steppes and partially zone of mountain plateau (“syrt”) of highland, the common species are argali (Ovis ammon poloi), ibex (Capra sibirica sakeen), snow leopard (Felis uncia), Tien Shan bear (Ursus arctos leuconyx), and red pica; very numerous are marmots and vole (Microtus gregalis). The bird fauna includes Himalayan snow-cock (Tetraogallus himalayensis), Alpine chough (Pyrrhocorax graculus), chough (P. pyrrhocorax), horned lark (Eremophila alpestris), rosefinch species. There are many waterfowl birds on the lakes. There are many Central Asian, particularly Tibetan species among the animals inhabiting highlands of the Tien Shan.
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Notes Full text available in RussianJournal Title: Physical geography of the USSR. Approved no
Call Number SLN @ rana @ 662 Serial 364
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Author Bobrinskiy N.A.
Title Mountains of Central Asia Type Miscellaneous
Year 1967 Publication Abbreviated Journal
Volume Issue Pages 296-321
Keywords Middle Asia; mountain; tien shan; Pamir; Hissar ridge; Turkestan ridge; Kopet-Dag ridge; Animals; plants; Issyk-Kul lake; Sary-Chelek; spiders; birds; lizards; marmots; wild sheep; ibex; snow leopard.; 6330; Russian
Abstract It provides a zoogeographical description of Central Asia mountains: Tien Shan (west and east), Pamir, the Turkestan and Hissar ridges, and ruinous mountains in Kyzylkum. Distribution of various animal species over the area under study is described. Data concerning Central Asia sheep, ibex, and snow leopard in the alpine meadow zone, and data concerning the otter (in the Tupalang river basin) and grey partridge is presented. The author noted that generally fauna of Tien Shan, Hissar, and Pamir is similar to that of Inner Asia. The other type of fauna more similar to that of Transcaucasia is typical for Kopet-Dag.
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Notes Full text available in RussianJournal Title: Fauna and nature of the USSR. Approved no
Call Number SLN @ rana @ 611 Serial 180
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Author Izold, J.
Title Snow Leopard Enterprise: a conservation project that saves an endangered species and supports needy families Type Journal Article
Year 2008 Publication Anim.Keepers' Forum Abbreviated Journal
Volume 9 Issue 5 Pages 359-364
Keywords snow; snow leopard; snow-leopard; leopard; conservation; project; endangered; endangered species; endangered-species; species; Support; union; uncia; Uncia uncia; Uncia-uncia; snow leopards; snow-leopards; leopards; wild; Iucn; Animals; Animal; tiger; extinction; former; zoo; Freeman; trust; work; cat; community-based; projects; Sle; impact; poverty; community; Mongolia; Kyrgyz; Kyrgyz-Republic; republic; Pakistan; 300; economic; incentives; prey; sustainable; herding; number; territory; income; training; products; wool; local; local people; people; zoos; Woodland-Park-Zoo; park; zoological; ecosystem
Abstract The World Conservation Union listed the snow leopard (Uncia uncia) as endangered in 1974. With as few as 3,500 snow leopards left in the wild, scientists placed the snow leopard on the IUCN Red List of critically endangered species shared by animals such as the giant panda and tiger. In an effort to save the snow leopard from extinction, former zoo employee Helen Freeman founded the Snow Leopard Trust in 1981. The Snow Leopard Trust works to save this elusive cat by incorporating community-based conservation projects. One of these project Leopard Enterprise (SLE), impacts poverty stricken communities in Mongolia, Kyrgyz Republic, and Pakistan. It assists over 300 families in its conservation efforts. The economic incentives provided via SLE have led participating communities not to harm the snow leopard or its prey, and to practice sustainable herding. Since the project began in 1997, the number of snow leopards harmed around the communities' territories has dropped to near zero. Additionally, the annual income of families that utilize the benefits of SLE has increased by 25% to 40%. SLE creates this economic benefit by providing the training and equipment necessary to make desirable products from the wool of herd animals. Snow Leopard Trust then purchases these handicraft items from the local people and them globally. Zoos can expand their conservation efforts by simply offering these items in their gift shops. Woodland Park Zoo (WPZ) was the first zoological institution to sell the products, and WPZ continues to generate revenue from them. SLE is a golden opportunity for zoos to increase revenue, assist poor families, and save an endangered species and fragile ecosystem.
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Publisher American Association of Zoo Keepers Place of Publication Topeka, Kansas Editor
Language Summary Language Original Title
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Notes Author from Cleveland Metroparks Zoo, Cleveland, OH, USA Approved no
Call Number SLN @ rana @ 976 Serial 425
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Author Barpiev I.M.
Title Peculiarities of biodiversity in the Besh-Aral nature reserve Type Miscellaneous
Year 2002 Publication Abbreviated Journal
Volume Issue Pages 25-26
Keywords Kyrgyzstan; Besh Aral nature reserve; Animals; endangered species; snow leopard.; 6170; Russian
Abstract 224 animal species, including two relict and 20 endemic, are registered in the Besh Aral nature reserve (Kyrgyzstan). This nature reserve is inhabited by rare and endangered animal and bird species (e.g. Menzbier's marmot, snow leopard, Tien Shan brown bear, manul, Turkistan lynx, saker falcon, bearded vulture, golden eagle, Himalayan griffon, and others) included in the Red Data Books of Kyrgyzstan, former USSR, and Led List of IUCN.
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Notes Full text available in RussianJournal Title: Biological diversity of the West Tien Shan. Approved no
Call Number SLN @ rana @ 595 Serial 120
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Author Bannikov A.G.
Title Mountains of Middle Asia and Kazakhstan Type Miscellaneous
Year 1966 Publication Abbreviated Journal
Volume Issue Pages 222-223
Keywords Middle Asia; Kazakhstan; nature reserves; plants; Animals; snow leopard; preys.; 6130
Abstract The data on geographical location, plants and animals of mountain nature reserves of Middle Asia and Kazakhstan are given. Snow leopard and its preys (wild ibexes and sheep) were recorded in both Almaty and Aksu Jabagly nature reserves.
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Notes Full text available in RussianJournal Title: Visiting of Soviet Union nature reserves. Approved no
Call Number SLN @ rana @ 591 Serial 112
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Author Pollock, R.V.; Carmichael, L.E.
Title Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus Type Journal Article
Year 1983 Publication Am J Vet Res Abbreviated Journal
Volume 44 Issue 2 Pages 169-175
Keywords Animal; Antibodies; Viral; biosynthesis; Dog; Diseases; microbiology; prevention; control; Dogs; Dose; Response; Relationship; Immunologic; Parvoviridae; immunology; Parvovirus; Feline; growth; development; Support; Non-U.S.Gov't; Vaccines; Attenuated; Virus; veterinary; Replication; browse; 350
Abstract Modified live feline panleukopenia virus (FPLV) vaccine protected dogs against canine parvovirus (CPV) infection. However, unlike the long- lived (greater than or equal to 20-month) immunity engendered by CPV infection, the response of dogs to living FPLV was variable. Doses of FPLV (snow leopard strain) in excess of 10(5.7) TCID50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. The duration of immunity, as measured by the persistence of hemagglutination-inhibiting antibody, was related to the magnitude of the initial response to vaccination; dogs with vigorous initial responses resisted oronasal CPV challenge exposure 6 months after vaccination, and hemagglutination-inhibiting antibodies persisted in such dogs for greater than 1 year. Limited replication of FPLV in dogs was demonstrated, but unlike CPV, the feline virus did not spread to contact dogs or cats. Adverse reactions were not associated with living FPLV vaccination, and FPLV did not interfere with simultaneous response to attenuated canine distemper virus.
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ISSN (up) 0002-9645 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 69 Serial 784
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Author Paul, H.A.; Bargar, W.L.; Leininger, R.
Title Total hip replacement in a snow leopard Type Journal Article
Year 1985 Publication J Am Vet Med Assoc Abbreviated Journal
Volume 187 Issue 11 Pages 1262-1263
Keywords Animal; Carnivora; surgery; Case; Report; Hip; Dislocation; veterinary; Prosthesis; Male; browse; 310
Abstract
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ISSN (up) 0003-1488 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 82 Serial 760
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Author White, S.D.; Stannard, A.A.; Ihrke, P.J.; Rosser, E.J.
Title Therapy of demodicosis in snow leopard challenged Type Journal Article
Year 1981 Publication J Am Vet Med Assoc Abbreviated Journal
Volume 178 Issue 9 Pages 877-878
Keywords Amoxicillin: therapeutic use; Animal; Animals; zoo; Calcium: therapeutic use; Carnivora; Mite Infestations: drug therapy; veterinary; Sulfides: therapeutic use; Thiosulfates: therapeutic use; amoxicillin; therapeutic; calcium; mite; infestations; drug; therapy; drug therapy; sulfides; thiosulfates; browse; use; 360
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 57 Serial 1020
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Author Mainka, S.A.
Title Bilateral separation of the olecranon and proximal epiphysis from the ulnar diaphysis in a snow leopard cub Type Journal Article
Year 1986 Publication J Am Vet Med Assoc Abbreviated Journal
Volume 189 Issue 9 Pages 1204-1205
Keywords Animal; Carnivora; injuries; Case-Report; Epiphyses; Forelimb; Male; Ulna; browse; 290
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 97 Serial 636
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Author Karesh, W.B.; Kunz, L.L.
Title Bilateral testicular seminoma in a snow leopard Type Journal Article
Year 1986 Publication J Am Vet Med Assoc Abbreviated Journal
Volume 189 Issue 9 Pages 1201
Keywords Animal; Carnivora; Case Report; Dysgerminoma; pathology; veterinary; Male; Testicular; neoplasms; Testis; browse; 300
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 98 Serial 514
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Author Brown, J.L.; Wasser, S.K.; Wildt, D.E.; Graham, L.H.
Title Comparative Aspects of Steroid Hormone Metabolism and Ovarian Activity in Felids, Measured Noninvasively in Feces Type Journal Article
Year 1994 Publication Biol Reprod Abbreviated Journal
Volume 51 Issue 4 Pages 776-786
Keywords Animal; Carbon; Radioisotopes; Carnivora; Cats; Chromatography; High; Pressure; Liquid; Comparative Study; Estradiol; metabolism; Estrone; feces; chemistry; Female; Ovary; physiology; Pregnancy; Progesterone; Pseudopregnancy; Support; Non-U.S.Gov't; browse; non; government; gov't; us; 170
Abstract Noninvasive fecal assays were used to study steroid metabolism and ovarian activity in several felid species. Using the domestic cat (Felis catus) as model, the excretory products of injected [14C]estradiol (E2) and [14C]progesterone (P4) were determined. Within 2 days, 97.0 +/- 0.6% and 96.7 +/- 0.5% of recovered E2 and P4 radioactivity, respectively, was found in feces. E2 was excreted as unconjugated estradiol and estrone (40%) and as a non-enzyme- hydrolyzable conjugate (60%). P4 was excreted primarily as non-enzyme- hydrolyzable, conjugated metabolites (78%) and as unconjugated pregnenolone epimers. A simple method for extracting fecal steroid metabolites optimized extraction efficiencies of the E2 and P4 excretion products (90.1 +/- 0.8% and 87.2 +/- 1.4%, respectively). Analysis of HPLC fractions of extracted fecal samples from the radiolabel-injected domestic cats revealed that E2 immunoreactivity coincided primarily with the unconjugated metabolized [14C]E2 peak, whereas progestogen immunoreactivity coincided with a single conjugated epimer and multiple unconjugated pregnenolone epimers. After HPLC separation, similar immunoreactive E2 and P4 metabolite profiles were observed in the leopard cat (F. bengalensis), cheetah (Acinonyx jubatus), clouded leopard (Neofelis nebulosa), and snow leopard (Panthera uncia). Longitudinal analyses demonstrated that changes in fecal E2 and P4 metabolite concentrations reflected natural or artificially induced ovarian activity. For example, severalfold increases in E2 excretion were associated with overt estrus or exogenous gonadotropin treatment, and elevated fecal P4 metabolite concentrations occurred during pregnant and nonpregnant (pseudopregnant) luteal phases. Although overall concentrations were similar, the duration of elevated fecal P4 metabolites during pseudopregnancy was approximately half that observed during pregnancy. In summary, steroid metabolism mechanisms appear to be conserved among these physically diverse, taxonomically related species. Results indicate that this hormone-monitoring approach will be extremely useful for elucidating the hormonal regulatory mechanism associated with the reproductive cycle, pregnancy, and parturition of intractable and endangered felid species.
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ISSN (up) 0006-3363 ISBN Medium
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Notes Document Type: eng Approved no
Call Number SLN @ rana @ 251 Serial 198
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