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Author Pfeil, A.; Lucker, H.; Pfeil, I.   
  Title Leiomyoma in the urinary bladder of a female snow leopard (Uncia uncia, Schreber, 1776) Type Journal Article
  Year 2004 Publication Tier„rztliche Praxis Kleintiere Abbreviated Journal  
  Volume 32 Issue 1 Pages 40-44  
  Keywords Bladder; captive; diagnostic; Female; german; leopard; origin; snow-leopard; snow-leopards; snow leopard; snow leopards; surgery; therapy; uncia; Uncia-uncia; Uncia uncia; urinary; veterinary; zoo  
  Abstract Summary

A leiomyoma of the urinary bladder in a 14-year-old female snow leopard exhibiting bloody vaginal discharge was removed by partial cystectomy. Gravel (struvite) was found in the urine of the inflammatory bladder. Additionally ovario-hysterectomy was performed. Histological findings showed a glandular-cystic hyperplasia. Tumors of the bladder are very rare in cats. Specifically the benign tumors of the bladder very often have no clinical relevance and rarely result in bladder dysfunction. Therefore they might remain undiagnosed in many cases, particularly since the diagnostic procedure in big cats is very extensive. Leiomyoma of the bladder in snow leopards have not been described yet. The present paper describes the surgery performed, the succeeding therapy, the struvit prophylaxis, and discusses the aetiology of the leiomyoma's origin on the basis of current literature. Zusammenfassung

Bei einer 14-j„hrigen Schneeleopardin mit blutigem Vaginalausfluss wurde ein Leiomyom der Blase durch partielle Zystektomie entfernt. Im Urin und in der entzndeten Blase konnte Grieá (Struvit) nachgewiesen werden. Gleichzeitig wurde eine Ovariohysterektomie durchgefhrt. Der histologische Befund ergab eine glandul„r-zystische Hyperplasie des Endometriums. Tumoren der Harnblase sind bei Katzen sehr selten. Vor allem benigne Blasentumoren haben oft keine klinische Relevanz und fhren selten zu Blasenfunktionsst”rungen. Es ist daher m”glich, dass sie insbesondere bei Groákatzen wegen der aufwendigen Diagnostik bersehen werden. Leiomyome in der Blase sind beim Schneeleoparden bisher nicht beschrieben. In diesem Artikel werden die durchgefhrte Operation, die folgende Therapie und Struvitprophylaxe beschrieben sowie m”gliche Žtiologien der Entstehung des Leiomyoms anhand der Literatur diskutiert.
 
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  Notes In German. Title: Leiomyom in der Blase bei einem weiblichen Schneeleoparden (Uncia uncia, Schreber, 1776). Aus dem Zoologischen Garten Dresden (Direktor: Dr. H. Lcker) und der Tier„rztlichen Klinik Dr. I. Pfeil, Dresden. Approved no  
  Call Number SLN @ rana @ 1055 Serial 772  
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Author Paul, H.A.; Bargar, W.L.; Leininger, R. url 
  Title Total hip replacement in a snow leopard Type Journal Article
  Year 1985 Publication J Am Vet Med Assoc Abbreviated Journal  
  Volume 187 Issue 11 Pages 1262-1263  
  Keywords Animal; Carnivora; surgery; Case; Report; Hip; Dislocation; veterinary; Prosthesis; Male; browse; 310  
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  ISSN 0003-1488 ISBN (down) Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 82 Serial 760  
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Author Munson, L.; Worley, M.B. url 
  Title Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks Type Journal Article
  Year 1991 Publication Vet Pathol Abbreviated Journal  
  Volume 28 Issue 1 Pages 37-45  
  Keywords Cirrhosis; epidemiology; Hemosiderosis; Hepadnaviridae; Hepatic; Hepatitis; pathology; Veno-Occlusive; veterinary; zoo  
  Abstract Livers from 54 snow leopards, 4 days to 23 years old, that had died in 23 US zoos, were evaluated histopathologically to determine if the hepatic fibrosis, which has been noted to be prevalent in this species, was due to chronic active hepatitis from hepadnaviral infection, Ito cell proliferation, or hemosiderosis. Forty-two of 54 snow leopards had subintimal vascular fibrosis with partial or total occlusion of central and sublobular veins (veno-occlusive disease) of unknown origin. All 21 leopards older than 5 years were affected. Four leopards had chronic active hepatitis, and 12 leopards had cholangiohepatitis; but these lesions were not connected anatomically to central and sublobular venous fibrosis. Hepatocellular and Kupffer cell siderosis and Ito cell proliferation were prevalent and often coexisted with perisinusoidal, central, and sublobular venous fibrosis; but fibrosis was present in leopards without siderosis or Ito cell proliferation. The pattern and prevalence of veno-occlusive disease in these leopards was similar to that reported in captive cheetah (Acinonyx jubatus), suggesting that a common extrinsic factor may cause the majority of hepatic disease in these large felid animals in captivity.  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 173 Serial 706  
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Author McVittie, R. url 
  Title Nursing behavior of snow leopard cubs Type Journal Article
  Year 1978 Publication Applied-Animal-Ethology Abbreviated Journal  
  Volume 4 Issue 2 Pages 159-168  
  Keywords suckling; behavior; veterinary; zoo; zoos; medical; browse; 1580  
  Abstract Reports that a preliminary project on nursing behavior in 3 young snow leopards revealed 2 phases in suckling pattern: nonnutritive and nutritive. The latter was distinguished by stereotypic rhythmical movements of the ears associated with swallowing. The cubs also demonstrated a teat preference, but the adaptive significance of such preferences and the accompanying agonistic behavior were unclear. (27 ref) (PsycINFO Database Record (c) 2000 APA, all rights reserved)(unassigned)  
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  Notes Document Type: English Approved no  
  Call Number SLN @ rana @ 37 Serial 669  
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Author Worley, M.B. url 
  Title Chronic liver disease in snow leopards: A possible viral etiology Type Book Chapter
  Year 1982 Publication International Pedigree Book of Snow Leopards, Vol. 3 Abbreviated Journal  
  Volume 3 Issue Pages 131-133  
  Keywords captive; Chronic; Disease; etiology; International; Liver; pedigree; snow-leopard; snow-leopards; snow leopard; snow leopards; veterinary; Viral; zoo  
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  Publisher Helsinki Zoo Place of Publication Helsinki Editor Blomqvist, L.  
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  Notes Approved no  
  Call Number SLN @ rana @ 1046 Serial 1030  
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Author Roth, T.L.; Armstrong, D.L.; Barrie, M.T.; Wildt, D.E. url 
  Title Seasonal effects on ovarian responsiveness to exogenous gonadotrophins and successful artificial insemination in the snow leopard (Uncia uncia) Type Journal Article
  Year 1997 Publication Reprod Fertil Dev Abbreviated Journal  
  Volume 9 Issue 3 Pages 285-295  
  Keywords Animal; Carnivora; anatomy; histology; Blood; physiology; Estradiol; Female; Gonadotropins; administration; dosage; pharmacology; Chorionic; Equine; Human; Insemination; artificial; methods; veterinary; Laparoscopy; Male; Oocytes; cytology; Ovary; drug; effects; Ovulation; Induction; Pregnancy; Progesterone; Seasons; Support; Non-U.S.Gov't; browse; non; us; gov't; government; 400  
  Abstract Ovaries of the seasonally-breeding snow leopard (Uncia uncia) were examined to determine whether they were responsive to exogenous gonadotrophins throughout the year. The potential of laparoscopic artificial insemination (AI) also was assessed for producing offspring. During the non-breeding, pre-breeding, breeding and post-breeding seasons, females (n = 20) were treated with a standardized, dual- hormone regimen given intramuscularly (600 I.U. of equine chorionic gonadotrophin followed 80-84 h later with 300 I.U. of human chorionic gonadotrophin (hCG)). Laparoscopy was performed 45-50 h after administration of hCG, and all ovarian structures were described. Females with fresh corpora lutea (CL) were inseminated, and anovulatory females were subjected to follicular aspiration to examine oocyte quality. Snow leopards responded to exogenous gonadotrophins throughout the year. Mean number of total ovarian structures (distinct follicles mature in appearance plus CL) did not differ (P > or = 0.05) with season, but the proportion of CL: total ovarian structures was greater (P < 0.01) for the breeding season compared with all other seasons. The proportion of females ovulating was greater (P < 0.05) during the breeding and post-breeding seasons than during the pre-breeding and non- breeding seasons respectively. No Grade-1 quality oocytes were recovered from follicles of anovulatory females. Serum concentrations of oestradiol-17 beta appeared elevated in all females, and neither oestradiol-17 beta concentrations nor progesterone concentrations differed (P > or = 0.05) among seasons. Of 15 females artificially inseminated, the only one that was inseminated in the non-breeding season became pregnant and delivered a single cub. This is the first successful pregnancy resulting from AI in this endangered species.  
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  ISSN 1031-3613 ISBN (down) Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 325 Serial 830  
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Author Ryan, J.A.; Roudebush, P.; Shores, J.   
  Title Laryngeal obstruction associated with cuterebrosis in a snow leopard (Felis-uncia) Type Journal Article
  Year 1990 Publication Journal of Zoo and Wildlife Medicine Abbreviated Journal  
  Volume 21 Issue 3 Pages 346-352  
  Keywords Cuterebrosis; medecine; veterinary; medical; zoo; zoos; medicine; browse; 1480  
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  Notes Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no  
  Call Number SLN @ rana @ 160 Serial 837  
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Author Schaffer, E.; Wiesner, H.; Von Hegel, G. url 
  Title Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) Type Journal Article
  Year 1988 Publication Tierarztl Prax Abbreviated Journal  
  Volume 16 Issue 1 Pages 87-91  
  Keywords Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german  
  Abstract In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin.  
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  ISSN 0303-6286 ISBN (down) Medium  
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  Notes Document Type: German Approved no  
  Call Number SLN @ rana @ 112 Serial 851  
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Author Schmidt, R.E.; Eisenbrandt, D.L.; Hubbard, G.B. url 
  Title Tyzzer's disease in snow leopards Type Journal Article
  Year 1984 Publication J Comp Pathol Abbreviated Journal  
  Volume 94 Issue 1 Pages 165-167  
  Keywords Animal; Animals; Newborn; zoo; Bacillus; Bacterial; Infections; pathology; veterinary; Carnivora; Liver; browse; 330  
  Abstract Tyzzer's disease was diagnosed histologically in 2 litters of newborn snow leopard kittens. The gross and histological lesions were similar to those reported in domestic cats and other animals. No signs of illness was noted in either of the snow leopard dams.  
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  ISSN 0021-9975 ISBN (down) Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 67 Serial 875  
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Author Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B. url 
  Title Feline papillomas and papillomaviruses Type Journal Article
  Year 2000 Publication Vet Pathol Abbreviated Journal  
  Volume 37 Issue 1 Pages 1-10  
  Keywords Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120  
  Abstract Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2).  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 385 Serial 948  
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