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Author |
Brown, J.L.; Wasser, S.K.; Wildt, D.E.; Graham, L.H. |
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Title |
Comparative Aspects of Steroid Hormone Metabolism and Ovarian Activity in Felids, Measured Noninvasively in Feces |
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Journal Article |
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Year |
1994 |
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Biol Reprod |
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51 |
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4 |
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776-786 |
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Animal; Carbon; Radioisotopes; Carnivora; Cats; Chromatography; High; Pressure; Liquid; Comparative Study; Estradiol; metabolism; Estrone; feces; chemistry; Female; Ovary; physiology; Pregnancy; Progesterone; Pseudopregnancy; Support; Non-U.S.Gov't; browse; non; government; gov't; us; 170 |
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Noninvasive fecal assays were used to study steroid metabolism and ovarian activity in several felid species. Using the domestic cat (Felis catus) as model, the excretory products of injected [14C]estradiol (E2) and [14C]progesterone (P4) were determined. Within 2 days, 97.0 +/- 0.6% and 96.7 +/- 0.5% of recovered E2 and P4 radioactivity, respectively, was found in feces. E2 was excreted as unconjugated estradiol and estrone (40%) and as a non-enzyme- hydrolyzable conjugate (60%). P4 was excreted primarily as non-enzyme- hydrolyzable, conjugated metabolites (78%) and as unconjugated pregnenolone epimers. A simple method for extracting fecal steroid metabolites optimized extraction efficiencies of the E2 and P4 excretion products (90.1 +/- 0.8% and 87.2 +/- 1.4%, respectively). Analysis of HPLC fractions of extracted fecal samples from the radiolabel-injected domestic cats revealed that E2 immunoreactivity coincided primarily with the unconjugated metabolized [14C]E2 peak, whereas progestogen immunoreactivity coincided with a single conjugated epimer and multiple unconjugated pregnenolone epimers. After HPLC separation, similar immunoreactive E2 and P4 metabolite profiles were observed in the leopard cat (F. bengalensis), cheetah (Acinonyx jubatus), clouded leopard (Neofelis nebulosa), and snow leopard (Panthera uncia). Longitudinal analyses demonstrated that changes in fecal E2 and P4 metabolite concentrations reflected natural or artificially induced ovarian activity. For example, severalfold increases in E2 excretion were associated with overt estrus or exogenous gonadotropin treatment, and elevated fecal P4 metabolite concentrations occurred during pregnant and nonpregnant (pseudopregnant) luteal phases. Although overall concentrations were similar, the duration of elevated fecal P4 metabolites during pseudopregnancy was approximately half that observed during pregnancy. In summary, steroid metabolism mechanisms appear to be conserved among these physically diverse, taxonomically related species. Results indicate that this hormone-monitoring approach will be extremely useful for elucidating the hormonal regulatory mechanism associated with the reproductive cycle, pregnancy, and parturition of intractable and endangered felid species. |
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0006-3363 |
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SLN @ rana @ 251 |
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198 |
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White, S.D.; Stannard, A.A.; Ihrke, P.J.; Rosser, E.J. |
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Title |
Therapy of demodicosis in snow leopard challenged |
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Journal Article |
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Year |
1981 |
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J Am Vet Med Assoc |
Abbreviated Journal |
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178 |
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9 |
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877-878 |
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Amoxicillin: therapeutic use; Animal; Animals; zoo; Calcium: therapeutic use; Carnivora; Mite Infestations: drug therapy; veterinary; Sulfides: therapeutic use; Thiosulfates: therapeutic use; amoxicillin; therapeutic; calcium; mite; infestations; drug; therapy; drug therapy; sulfides; thiosulfates; browse; use; 360 |
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0003-1488 |
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SLN @ rana @ 57 |
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1020 |
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Johnston, L.A.; Donoghue, A.M.; O'Brien, S.J.; Wildt, D.E. |
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Title |
Rescue and maturation in vitro of follicular oocytes collected from nondomestic felid species |
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Journal Article |
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1991 |
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Biol Reprod |
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45 |
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6 |
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898-906 |
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Animal; Carnivora; anatomy; histology; physiology; Cells; Cultured; Female; Fertilization; Vitro; inVitro; Male; Oocytes; cytology; growth; development; ovarian; Follicle; Spermatozoa; Support; Non-U.S.Gov't; U.S.Gov't; P.H.S.; browse; non; us; gov't; government; 230 |
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The potential for rescuing immature oocytes from the ovaries of females of rare felid species which die or undergo medical ovariohysterectomy was evaluated. Ovaries were recovered from 13 species representing 35 individuals in good-to-poor health. Although the majority of females were 10 yr of age or older and in fair-to-poor health, a total of 846 oocytes were recovered of which 608 (71.9%) were classified as fair-to- excellent quality. One hundred of these oocytes were used for initial maturation classification and as parthogenetic controls. Overall, of the 508 fair-to-excellent quality oocytes placed in culture, 164 (32.3%) matured to metaphase II in vitro. For species in which 3 or more individuals yielded oocytes, mean oocyte maturation rates were as follows: 36.2%, tiger; 27.9% leopard; and 8.3%, cheetah. In vitro insemination of oocytes resulted in fertilization (2 polar bodies, 2 pronuclei, or cleavage) rates of 9.1% to 28.6% (leopard) using homologous fresh spermatozoa and 4.0% (lion) to 40.0% (puma) using homologous frozen-thawed spermatozoa. Inseminations using heterologous (domestic cat) spermatozoa also resulted in fertilized oocytes in the tiger, leopard, snow leopard, puma, serval, and Geoffroy's cat (range in fertilization rate, 5.0% for leopard to 46.2% for puma). Cleaved embryos resulted from the insemination of leopard oocytes with homologous sperm (n = 1 embryo) and puma oocytes with domestic cat sperm (n = 3 embryos). These results demonstrate that immature ovarian oocytes from rare felid species can be stimulated to mature in vitro despite an excision-to-culture interval as long as 36 h.(ABSTRACT TRUNCATED AT 250 WORDS) |
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0006-3363 |
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Document Type: eng |
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SLN @ rana @ 172 |
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503 |
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Author |
Karesh, W.B.; Kunz, L.L. |
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Title |
Bilateral testicular seminoma in a snow leopard |
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Journal Article |
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Year |
1986 |
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J Am Vet Med Assoc |
Abbreviated Journal |
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189 |
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9 |
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1201 |
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Animal; Carnivora; Case Report; Dysgerminoma; pathology; veterinary; Male; Testicular; neoplasms; Testis; browse; 300 |
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0003-1488 |
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Document Type: eng |
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SLN @ rana @ 98 |
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514 |
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Author |
Mainka, S.A. |
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Title |
Bilateral separation of the olecranon and proximal epiphysis from the ulnar diaphysis in a snow leopard cub |
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Journal Article |
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1986 |
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J Am Vet Med Assoc |
Abbreviated Journal |
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189 |
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9 |
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1204-1205 |
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Animal; Carnivora; injuries; Case-Report; Epiphyses; Forelimb; Male; Ulna; browse; 290 |
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0003-1488 |
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SLN @ rana @ 97 |
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636 |
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Paul, H.A.; Bargar, W.L.; Leininger, R. |
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Title |
Total hip replacement in a snow leopard |
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Journal Article |
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1985 |
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J Am Vet Med Assoc |
Abbreviated Journal |
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187 |
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11 |
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1262-1263 |
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Animal; Carnivora; surgery; Case; Report; Hip; Dislocation; veterinary; Prosthesis; Male; browse; 310 |
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0003-1488 |
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Document Type: eng |
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SLN @ rana @ 82 |
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760 |
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Author |
Ale, S.; Brown, J. |
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Title |
The contingencies of group size and vigilance |
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Miscellaneous |
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2007 |
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Evolutionary Ecology Research, |
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9 |
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1263-1276 |
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attraction effect,contingency,dilution effect,fitness,group-size effect,many-eyes effect,predation risk,vigilance behaviour; predation; decline; potential; predators; predator; feeding; Animals; Animal; use; food; effects; Relationship; behaviour; methods; game; Interactions; interaction; factor; value; Energy |
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Background: Predation risk declines non-linearly with one's own vigilance and the vigilance of others in the group (the 'many-eyes' effect). Furthermore, as group size increases, the individual's risk of predation may decline through dilution with more potential victims, but may increase if larger groups attract more predators. These are known, respectively, as the dilution effect and the attraction effect.
Assumptions: Feeding animals use vigilance to trade-off food and safety. Net feeding rate declines linearly with vigilance.
Question: How do the many-eyes, dilution, and attraction effects interact to influence the relationship between group size and vigilance behaviour?
Mathematical methods: We use game theory and the fitness-generating function to determine the ESS level of vigilance of an individual within a group.
Predictions: Vigilance decreases with group size as a consequence of the many-eyes and dilution effects but increases with group size as a consequence of the attraction effect, when they act independent of each other. Their synergetic effects on vigilance depend upon the relative strengths of each and their interactions. Regardless, the influence of other factors on vigilance – such as encounter rate with predators, predator lethality, marginal value of energy, and value of vigilance – decline with group size. |
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SLN @ rana @ 886 |
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53 |
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Kleinman, M.S.; Garman, R.H. |
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Title |
An endoscopic approach to a snow leopard |
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1978 |
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Gastroenterology |
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74 |
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6 |
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1348 |
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Animal; Bezoars; veterinary; Carnivora; Cats; Esophagoscopy; Male; browse; 370 |
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0016-5085 |
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SLN @ rana @ 47 |
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536 |
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Woodroffe, R.; Ginsberg, J.R. |
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Title |
Edge effects and the extinction of populations inside protected areas |
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Journal Article |
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1998 |
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Science Washington D.C. |
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280 |
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5372 |
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2126-2128 |
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edge-effects; extinction; human-animal-conflict; mortality; population-size; protected-areas; browse; edge effects; Human; Animal; conflict; population; protected; area; 590 |
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Theory predicts that small populations may be driven to extinction by random fluctuations in demography and loss of genetic diversity through drift. However, population size is a poor predictor of extinction in large carnivores inhabiting protected areas. Conflict with people on reserve borders is the major cause of mortality in such populations, so that border areas represent population sinks. The species most likely to disappear from small reserves are those that range widely-and are therefore most exposed to threats on reserve borders-irrespective of population size. Conservation efforts that combat only stochastic processes are therefore unlikely to avert extinction. |
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Document Type: English |
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SLN @ rana @ 351 |
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1028 |
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Chandra, S.; Laughlin, D.C. |
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Virus-like particles in cystic mammary adenoma of a snow leopard |
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Journal Article |
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1975 |
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Cancer Res |
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35 |
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11 Pt 1 |
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3069-3074 |
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Adenoma pathology veterinary; Animal; Animals; zoo; Carnivora; Cytoplasmic Granules; Endoplasmic Reticulum: ultrastructure; Inclusion Bodies; Mammae: pathology; Neoplasms: pathology: veterinary; neoplasms; pathology; mammae; inclusion; bodies; ultrastructure; reticulum; endoplasmic; granules; cytoplasmic; adenoma; veterinary; browse; 380 |
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Virus-like particles were observed in the giant cells of a mammary adenoma of a snow leopard kept in captivity. Particles that measured 115 to 125 nm in diameter budded from the lamella of endoplasmic reticulum and were studded on their inner surfaces with dense granules (approximately 12 nm) that gave them their unique ultrastructural morphology. Such particles were not observed extracellularly. Type B or type C particles were not seen in the tumor tissue. |
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0008-5472 |
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SLN @ rana @ 27 |
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212 |
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