Abstract: Two adult snow leopards (Panthera uncia), male and female, both with vaccinations current, became infected with feline panleukopenia virus (FPV) at the Blank Park Zoo, Des Moines, Iowa, in late 1988. Clinical signs included weakness, hemorrhagic feces, fever, seizures, and nasal discharge. Blood analysis revealed severe lymphopenia and mild anemia. A positive enzyme-linked immunosorbent assay (ELISA) test for FPV on fecal contents from the male leopard confirmed the diagnosis. In spite of intensive therapy, both animals died. Necropsy of the female, which survived for 1 wk after onset of signs, revealed intestinal crypt necrosis, pulmonary consolidation, necrotizing laryngitis, and diffuse lymphoid depletion. The male leopard, which lived 3 wk after onset of illness, had similar enteric and lymphoid lesions. In addition, there was a severe interstitial pneumonia, with syncytial cells containing eosinophilic intracytoplasmic inclusion bodies. Ultrastructural characteristics of these inclusions featured tubular structures consistent with a paramyxovirus. Although repeated virus isolation attempts from the affected lung were negative, polyclonal and monoclonal fluorescent antibody tests were strongly positive for canine distemper virus (CDV). Frozen paired sera from each leopard demonstrated very high acute and convalescing titers to FPV; both animals also seroconverted to CDV, with titers in the male leopard higher than those in the female. Additional tests for toxoplasmosis, feline infectious peritonitis, feline rhinotracheitis, feline calicivirus, feline leukemia, canine parainfluenza, and bovine respiratory syncytial virus were all negative. The neurologic signs present in these leopards remained unexplained, but may have been attributable to CDV infection. A feral cat trapped on zoo property had feces positive for FPV by ELISA. Although the specific contributions of FPV and CDV toward the development of this case are unknown, it is likely that initial FPV-induced immunosuppression allowed the subsequent development of CDV in these snow leopards. The likelihood that initial FPV infection came from feral cats underscores the importance of feral animal control on zoo premises.

Abstract: Changes in economy and land use are under way in the Indian Transhimalayan region of Ladakh, creating both negative and positive prospects for wildlife conservation in this sparsely populations and previously remote area. New livestock breeds, irrigation developments, farming practices, foreign tourists, and a large military presence are changing the way people view and use the mountainous land that surrounds them. With only 0.3% of the land currently arable, changes in wildlife and natural resource conservation are most apparent on Ladakh's extensive rangelands which are apparently undergoing a redistribution of use associated with social changes and recently introduced animal husbandry and farming practices. International endangered species such as the snow leopard, several wild ungulates, and the black-necked crane provide special incentive for conservation efforts in what are some of the best remaining natural areas in the mountainous regions to the north of the Himalayan crest. The success of newly created protected areas for wildlife conservation in Ladakh rests on an understanding of the effects of various development directions, a commitment to environmentally sensitive development amid the many competing demands on Ladakh's natural resources, conservation laws appropriate to human needs, and a clear recognition that solutions can be neither directly adaptable from other mountainous areas nor even widely applicable across the Himalayan region.

Abstract: During a six-week period in Hemis National Park, Ladakh, India, snow leopards killed 10 sheep and goats and one leopard gained access to a livestock pen and killed many of the animals inside. Dholes also killed sheep and goats, and a wolf killed a young horse. Residents routinely remove snow leopard cubs from their dens to limit future damage by this species. How to deal with the plight of the people living in the area while still protecting the endangered species are major concerns of the International Snow Leopard Trust, which manages Hemis National Park. lgh.

Abstract: Indicates that snow leopard range includes all of Northern Bhutan