Abstract: Being one of nine nature reserves in Uzbekistan, Chatkal was established in 1947. Its area changed its size and administrative jurisdiction. Foothills adjacent to the nature reserve were long ago inhabited and developed by people. In Middle Ages, the area of juniperous forest reduced considerably because of mining operations. There are rare mammal species in the nature reserve, such as snow leopard, bear, Menzbier's marmot, and six rare bird species