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Author  |
Chandra, S.; Laughlin, D.C. |
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Title |
Virus-like particles in cystic mammary adenoma of a snow leopard |
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Journal Article |
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Year |
1975 |
Publication |
Cancer Res |
Abbreviated Journal |
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Volume |
35 |
Issue |
11 Pt 1 |
Pages |
3069-3074 |
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Keywords |
Adenoma pathology veterinary; Animal; Animals; zoo; Carnivora; Cytoplasmic Granules; Endoplasmic Reticulum: ultrastructure; Inclusion Bodies; Mammae: pathology; Neoplasms: pathology: veterinary; neoplasms; pathology; mammae; inclusion; bodies; ultrastructure; reticulum; endoplasmic; granules; cytoplasmic; adenoma; veterinary; browse; 380 |
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Abstract |
Virus-like particles were observed in the giant cells of a mammary adenoma of a snow leopard kept in captivity. Particles that measured 115 to 125 nm in diameter budded from the lamella of endoplasmic reticulum and were studded on their inner surfaces with dense granules (approximately 12 nm) that gave them their unique ultrastructural morphology. Such particles were not observed extracellularly. Type B or type C particles were not seen in the tumor tissue. |
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0008-5472 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 27 |
Serial |
212 |
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Author |
Doster, A.R.; Armstrong, D.L.; Bargar, T.W. |
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Title |
Seminoma and parathyroid adenoma in a snow leopard (Panthera unica) |
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Journal Article |
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Year |
1989 |
Publication |
J Comp Pathol |
Abbreviated Journal |
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Volume |
100 |
Issue |
4 |
Pages |
475-480 |
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Keywords |
Adenoma: pathology: veterinary; Animal; Carnivora; Dysgerminoma; pathology; veterinary; Male; Microscopy; Electron; neoplasms; Multiple Primary; Parathyroid; Testicular Neoplasms; adenoma; multiple; primary; Testicular; browse; 250 |
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Abstract |
A seminoma and parathyroid adenoma were diagnosed in an aged snow leopard. The ultrastructural appearance of the seminoma was similar to that described in the dog and in man. The lack of significant amounts of rough endoplasmic reticulum, Golgi complexes and free ribosomes in the parathyroid adenoma suggested that it was non-functional. Parathyroid adenoma has not been previously described in a large wild feline. |
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0021-9975 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 142 |
Serial |
244 |
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Author |
Gosselin, S.J.; Loudy, D.L.; Tarr, M.J.; Balistreri, W.F.; Setchell, K.D.; Johnston, J.O.; Kramer, L.W.; Dresser, B.L. |
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Title |
Veno-occlusive disease of the liver in captive cheetah |
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Journal Article |
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Year |
1988 |
Publication |
Vet Pathol |
Abbreviated Journal |
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Volume |
25 |
Issue |
1 |
Pages |
48-57 |
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Keywords |
Animal; Feed; analysis; Carnivora; Cheetahs; Female; Hepatic; Veno; Occlusive; Disease; pathology; veterinary; Histocytochemistry; Liver; ultrastructure; Male; Microscopy; Electron; Support; Non-U.S.Gov't; Vitamin A; browse; non; us; gov't; government; 280 |
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Abstract |
Liver tissues from 126 captive cheetah were evaluated by light microscopy and histochemistry; eight animals were evaluated by electron microscopy. The main hepatic lesion, a vascular lesion resembling veno- occlusive disease (VOD) of the liver and characterized by subendothelial fibrosis and proliferation of smooth muscle-like cells in the central veins, was seen in 60% of the sexually mature cheetah. Although this hepatic vascular lesion was seen in cheetah as young as 1 year of age, the most severe lesions, usually associated with liver failure, were found in cheetah between the ages of 6 and 11. There was no sex predisposition, and in approximately 40% of the VOD cases, liver disease was not suspected clinically or at necropsy. VOD was found in other felidae, especially in the snow leopard. High levels of vitamin A in livers, as well as in diets of the cheetah, could be a contributing factor in the development of VOD in some groups of cheetah. |
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0300-9858 |
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Document Type: Eng |
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no |
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Call Number |
SLN @ rana @ 127 |
Serial |
339 |
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Author |
Karesh, W.B.; Kunz, L.L. |
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Title |
Bilateral testicular seminoma in a snow leopard |
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Journal Article |
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Year |
1986 |
Publication |
J Am Vet Med Assoc |
Abbreviated Journal |
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Volume |
189 |
Issue |
9 |
Pages |
1201 |
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Keywords |
Animal; Carnivora; Case Report; Dysgerminoma; pathology; veterinary; Male; Testicular; neoplasms; Testis; browse; 300 |
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0003-1488 |
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Document Type: eng |
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no |
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Call Number |
SLN @ rana @ 98 |
Serial |
514 |
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Author |
Munson, L.; Worley, M.B. |
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Title |
Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks |
Type |
Journal Article |
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Year |
1991 |
Publication |
Vet Pathol |
Abbreviated Journal |
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Volume |
28 |
Issue |
1 |
Pages |
37-45 |
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Keywords |
Cirrhosis; epidemiology; Hemosiderosis; Hepadnaviridae; Hepatic; Hepatitis; pathology; Veno-Occlusive; veterinary; zoo |
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Abstract |
Livers from 54 snow leopards, 4 days to 23 years old, that had died in 23 US zoos, were evaluated histopathologically to determine if the hepatic fibrosis, which has been noted to be prevalent in this species, was due to chronic active hepatitis from hepadnaviral infection, Ito cell proliferation, or hemosiderosis. Forty-two of 54 snow leopards had subintimal vascular fibrosis with partial or total occlusion of central and sublobular veins (veno-occlusive disease) of unknown origin. All 21 leopards older than 5 years were affected. Four leopards had chronic active hepatitis, and 12 leopards had cholangiohepatitis; but these lesions were not connected anatomically to central and sublobular venous fibrosis. Hepatocellular and Kupffer cell siderosis and Ito cell proliferation were prevalent and often coexisted with perisinusoidal, central, and sublobular venous fibrosis; but fibrosis was present in leopards without siderosis or Ito cell proliferation. The pattern and prevalence of veno-occlusive disease in these leopards was similar to that reported in captive cheetah (Acinonyx jubatus), suggesting that a common extrinsic factor may cause the majority of hepatic disease in these large felid animals in captivity. |
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0300-9858 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 173 |
Serial |
706 |
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Author |
Schaffer, E.; Wiesner, H.; Von Hegel, G. |
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Title |
Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) |
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Journal Article |
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Year |
1988 |
Publication |
Tierarztl Prax |
Abbreviated Journal |
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Volume |
16 |
Issue |
1 |
Pages |
87-91 |
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Keywords |
Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german |
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Abstract |
In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin. |
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0303-6286 |
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Document Type: German |
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Call Number |
SLN @ rana @ 112 |
Serial |
851 |
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Author |
Schmidt, R.E.; Eisenbrandt, D.L.; Hubbard, G.B. |
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Title |
Tyzzer's disease in snow leopards |
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Journal Article |
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Year |
1984 |
Publication |
J Comp Pathol |
Abbreviated Journal |
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Volume |
94 |
Issue |
1 |
Pages |
165-167 |
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Keywords |
Animal; Animals; Newborn; zoo; Bacillus; Bacterial; Infections; pathology; veterinary; Carnivora; Liver; browse; 330 |
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Tyzzer's disease was diagnosed histologically in 2 litters of newborn snow leopard kittens. The gross and histological lesions were similar to those reported in domestic cats and other animals. No signs of illness was noted in either of the snow leopard dams. |
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0021-9975 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 67 |
Serial |
875 |
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Author |
Sundberg, J.P.; Van Ranst, M.; Montali, R.; Homer, B.L.; Miller, W.H.; Rowland, P.H.; Scott, D.W.; England, J.J.; Dunstan, R.W.; Mikaelian, I.; Jenson, A.B. |
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Title |
Feline papillomas and papillomaviruses |
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Journal Article |
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Year |
2000 |
Publication |
Vet Pathol |
Abbreviated Journal |
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Volume |
37 |
Issue |
1 |
Pages |
1-10 |
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Keywords |
Animal; Antibodies; Monoclonal; Carnivora; pathology; virology; Cats; Dna; Viral; chemistry; Epitope; Mapping; veterinary; Female; Immunohistochemistry; Lions; Male; Microscopy; Electron; Papilloma; Papillomavirus; Papovaviridae; Infections; skin; neoplasms; Tongue; browse; 120 |
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Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are rarely reported, we identified productive infections in six cat species. PV-induced proliferative skin or mucous membrane lesions were confirmed by immunohistochemical screening for papillomavirus-specific capsid antigens. Seven monoclonal antibodies, each of which reacts with an immunodominant antigenic determinant of the bovine papillomavirus L1 gene product, revealed that feline PV capsid epitopes were conserved to various degrees. This battery of monoclonal antibodies established differential expression patterns among cutaneous and oral PVs of snow leopards and domestic cats, suggesting that they represent distinct viruses. Clinically, the lesions in all species and anatomic sites were locally extensive and frequently multiple. Histologically, the areas of epidermal hyperplasia were flat with a similarity to benign tumors induced by cutaneotropic, carcinogenic PVs in immunosuppressed human patients. Limited restriction endonuclease analyses of viral genomic DNA confirmed the variability among three viral genomes recovered from available frozen tissue. Because most previous PV isolates have been species specific, these studies suggest that at least eight different cat papillomaviruses infect the oral cavity (tentative designations: Asian lion, Panthera leo, P1PV; snow leopard, Panthera uncia, PuPV-1; bobcat, Felis rufus, FrPV; Florida panther, Felis concolor, FcPV; clouded leopard, Neofelis nebulosa, NnPV; and domestic cat, Felis domesticus, FdPV-2) or skin (domestic cat, F. domesticus, FdPV-1; and snow leopard, P. uncia, PuPV-2). |
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0300-9858 |
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Document Type: eng |
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Call Number |
SLN @ rana @ 385 |
Serial |
948 |
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