| Records |
| Author |
Brown, J.L.; Wasser, S.K.; Wildt, D.E.; Graham, L.H. |
| Title |
Comparative Aspects of Steroid Hormone Metabolism and Ovarian Activity in Felids, Measured Noninvasively in Feces |
Type |
Journal Article |
| Year |
1994 |
Publication |
Biol Reprod |
Abbreviated Journal |
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| Volume |
51 |
Issue |
4 |
Pages |
776-786 |
| Keywords |
Animal; Carbon; Radioisotopes; Carnivora; Cats; Chromatography; High; Pressure; Liquid; Comparative Study; Estradiol; metabolism; Estrone; feces; chemistry; Female; Ovary; physiology; Pregnancy; Progesterone; Pseudopregnancy; Support; Non-U.S.Gov't; browse; non; government; gov't; us; 170 |
| Abstract |
Noninvasive fecal assays were used to study steroid metabolism and ovarian activity in several felid species. Using the domestic cat (Felis catus) as model, the excretory products of injected [14C]estradiol (E2) and [14C]progesterone (P4) were determined. Within 2 days, 97.0 +/- 0.6% and 96.7 +/- 0.5% of recovered E2 and P4 radioactivity, respectively, was found in feces. E2 was excreted as unconjugated estradiol and estrone (40%) and as a non-enzyme- hydrolyzable conjugate (60%). P4 was excreted primarily as non-enzyme- hydrolyzable, conjugated metabolites (78%) and as unconjugated pregnenolone epimers. A simple method for extracting fecal steroid metabolites optimized extraction efficiencies of the E2 and P4 excretion products (90.1 +/- 0.8% and 87.2 +/- 1.4%, respectively). Analysis of HPLC fractions of extracted fecal samples from the radiolabel-injected domestic cats revealed that E2 immunoreactivity coincided primarily with the unconjugated metabolized [14C]E2 peak, whereas progestogen immunoreactivity coincided with a single conjugated epimer and multiple unconjugated pregnenolone epimers. After HPLC separation, similar immunoreactive E2 and P4 metabolite profiles were observed in the leopard cat (F. bengalensis), cheetah (Acinonyx jubatus), clouded leopard (Neofelis nebulosa), and snow leopard (Panthera uncia). Longitudinal analyses demonstrated that changes in fecal E2 and P4 metabolite concentrations reflected natural or artificially induced ovarian activity. For example, severalfold increases in E2 excretion were associated with overt estrus or exogenous gonadotropin treatment, and elevated fecal P4 metabolite concentrations occurred during pregnant and nonpregnant (pseudopregnant) luteal phases. Although overall concentrations were similar, the duration of elevated fecal P4 metabolites during pseudopregnancy was approximately half that observed during pregnancy. In summary, steroid metabolism mechanisms appear to be conserved among these physically diverse, taxonomically related species. Results indicate that this hormone-monitoring approach will be extremely useful for elucidating the hormonal regulatory mechanism associated with the reproductive cycle, pregnancy, and parturition of intractable and endangered felid species. |
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| ISSN |
0006-3363 |
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Document Type: eng |
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no |
| Call Number |
SLN @ rana @ 251 |
Serial |
198 |
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| Author |
De Groot, H.; Van Swieten, P.; Aalberse, R.C. |
| Title |
Evidence for a Fel d I-like molecule in the “big cats” (Felidae species) |
Type |
Journal Article |
| Year |
1990 |
Publication |
J Allergy Clin Immunol |
Abbreviated Journal |
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| Volume |
86 |
Issue |
1 |
Pages |
107-116 |
| Keywords |
Adolescence; Adult; Allergens; immunology; Animal; Antibodies; Monoclonal; diagnostic; use; Antibody; Specificity; Carnivora; Cats; Comparative; study; Cross; Reactions; Hair; Histamine; Release; Human; IgE; analysis; IgG; Middle; Age; Radioallergosorbent; Test; methods; Support; Non-U.S.Gov't; browse; us; government; gov't; 240 |
| Abstract |
In this study, we investigated the cross-reactivity pattern of IgE and IgG4 antibodies to the major feline allergen, Fel d I. We studied the IgE and IgG4 response of 11 cat-allergic patients against Fel d I-like structures in eight members of the Felidae family: ocelot, puma, serval, siberian tiger, lion, jaguar, snow leopard, and caracal. Hair from these “big cats” was collected, extracted, and used in a RAST system and histamine-release test. By means of a RAST-inhibition assay with affinity-purified Fel d I from cat dander, it was established that, in the Felidae species, a Fel d I equivalent is present that reacts with IgE and IgG4 antibodies. We found that all patients had cross-reacting IgE antibodies to seven of the Felidae tested; no IgE antibodies reactive with the caracal were found. Eight of 10 patients with IgG4 antibodies directed to cat dander also had IgG4 antibodies directed to several Felidae species, including the caracal. However, the correlation between the IgE and the IgG4 antibody specificity was low, indicating that, in the case of Fel d I IgE and IgG4, antibodies do not necessarily have the same specificity. |
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0091-6749 |
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Document Type: eng |
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no |
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SLN @ rana @ 157 |
Serial |
233 |
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| Author |
Hast, M.H. |
| Title |
The larynx of roaring and non-roaring cats |
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Journal Article |
| Year |
1989 |
Publication |
J Anat |
Abbreviated Journal |
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| Volume |
163 |
Issue |
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Pages |
117-121 |
| Keywords |
Animal; Carnivora; anatomy; histology; Cats; Comparative; study; Female; Larynx; physiology; Lions; Male; Vocal; Cords; vocalization; browse; 260 |
| Abstract |
Dissections were made of the larynges of 14 species of the cat family, with representative specimens from all genera. It was found that the vocal folds of the larynx of genus Panthera (with the exception of the snow leopard) form the basic structure of a sound generator well- designed to produce a high acoustical energy. Combined with an efficient sound radiator (vocal tract) that can be adjusted in length, a Panthera can use its vocal instrument literally to blow its own horn with a 'roar'. Also, it is proposed that laryngeal morphology can be used as an anatomical character in mammalian taxonomy. |
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0021-8782 |
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| Notes |
Document Type: eng |
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no |
| Call Number |
SLN @ rana @ 143 |
Serial |
374 |
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| Author |
Hochstrasser, K.; Wachter, E.; Reisinger, P.W.; Greim, M.; Albrecht, G.J.; Gebhard, W. |
| Title |
Amino acid sequences of mammalian kazal-type proteinase inhibitors from salivary glands |
Type |
Journal Article |
| Year |
1993 |
Publication |
Comp Biochem Physiol B |
Abbreviated Journal |
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| Volume |
106 |
Issue |
1 |
Pages |
103-108 |
| Keywords |
Amino; Acid; Sequence; Animal; Carnivora; Comparative; study; Cysteine; chemistry; Glycosylation; Mink; Molecular; Data; Protease; Inhibitors; Salivary; Proteins; species; Specificity; Submandibular; Gland; Trypsin; Inhibitor; Kazal; Pancreatic; browse; 200 |
| Abstract |
1. The amino acid sequences of bikazins (the double-headed Kazal-type proteinase inhibitors from submandibular glands) isolated from the snow leopard (Unica unica), the European mink (Mustela lutreola), and the European pine marten (Martes martes) were determined. 2. N-terminal domains of bikazins are characterized by a cysteine residue spacing that differs from that of C-terminal domains of bikazins and other Kazal-type proteinase inhibitor domains. 3. N-terminal sequences of bikazins seem to be specific for, and highly conserved within, each Carnivora family. |
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0305-0491 |
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Document Type: eng |
Approved |
no |
| Call Number |
SLN @ rana @ 202 |
Serial |
385 |
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| Author |
Johnston, L.A.; Armstrong, D.L.; Brown, J.L. |
| Title |
Seasonal effects on seminal and endocrine traits in the captive snow leopard (Panthera uncia) |
Type |
Journal Article |
| Year |
1994 |
Publication |
J Reprod Fertil |
Abbreviated Journal |
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| Volume |
102 |
Issue |
1 |
Pages |
229-236 |
| Keywords |
Animal; Carnivora; physiology; Comparative; study; Fsh; Blood; Gonadotropins; Pituitary; Lh; Male; Seasons; Semen; Sperm; Motility; Spermatozoa; cytology; Testosterone; browse; 180 |
| Abstract |
The annual reproductive cycle of the male snow leopard (Panthera uncia) was characterized by evaluating seminal and endocrine traits monthly. Testicular volume was greatest (P < 0.05) during the winter months when the quality of ejaculate was optimal. Ejaculate volume, total sperm concentration ml-1, motile sperm concentration per ejaculate, sperm morphology and sperm motility index were lowest during the summer and autumn months compared with the winter and spring. Peripheral LH, FSH and testosterone concentrations were also lowest during the summer months, increasing during the autumn just before the increase in semen quality, and were maximal during the winter months. There was a direct relationship (P < 0.01) between: (1) testosterone and testicular volume, total sperm concentration ml-1, motile sperm concentration per ejaculate and ejaculate volume, and (2) LH and testicular volume and motile sperm concentration per ejaculate. In summary, although spermatozoa were recovered throughout the year, optimal gamete quality was observed during the winter and spring. Although previous studies in felids have demonstrated seasonal effects on either seminal or endocrine traits, this is the first study to demonstrate a distinct effect of season on both pituitary and testicular function. |
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0022-4251 |
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Document Type: eng |
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no |
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SLN @ rana @ 252 |
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504 |
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| Author |
Lui, C.-guang; Zheng, C.-wu; Ren, J.-rang |
| Title |
Research Foods and Food Sources About Snow Leopard (Panthera uncia) |
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Miscellaneous |
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2003 |
Publication |
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Abbreviated Journal |
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31 |
Issue |
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Pages |
154-159 |
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research; foods; food; snow; snow leopard; snow-leopard; leopard; panthera; panthera uncia; Panthera-uncia; uncia; Chinese; deer; kiang; argali; Qinghai; gansu; Sichuan; Comparative; congruence; species; distribution; variation |
| Abstract |
During 1984-1987, 1992-1995, and 1998-2001, the author researched snow leopard, white lipped deer, kiang, and argali in Qinghai, Gansu, Xingiang, and Sichuan. He collected 644 snow leopard droppings, and analyzed kinds of foods and sources from perch. Snow leopard's foods include most main foods, main foods, comparative foods and lesser foods. Studied one another
index of faunistic congruence of foods species that from various distribution and variation both perch vertical variety and foods of snow leopard. |
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Full text available in Chinese. Periodical: Journal of Shaanxi Normal University (Natural Science Edition) |
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no |
| Call Number |
SLN @ rana @ 877 |
Serial |
626 |
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| Author |
Roth, T.L.; Howard, J.G.; Donoghue, A.M.; Swanson, W.F.; Wildt, D.E. |
| Title |
Function and culture requirements of snow leopard (Panthera uncia) spermatozoa in vitro |
Type |
Journal Article |
| Year |
1994 |
Publication |
J Reprod Fertil |
Abbreviated Journal |
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| Volume |
101 |
Issue |
3 |
Pages |
563-569 |
| Keywords |
Animal; Carnivora; physiology; Cell; survival; Cells; Cultured; Comparative; study; Culture; Media; Female; Male; Pentoxifylline; Sperm; Motility; Ovum; Interactions; Spermatozoa; cytology; Support; Non-U.S.Gov't; U.S.Gov't; P.H.S.; browse; non; us; gov't; government; 190 |
| Abstract |
Electroejaculates from eight snow leopards were used to determine how the motility of spermatozoa was influenced by (i) type of media (Ham's F10, PBS, human tubal fluid or RPMI-1640); (ii) holding temperature (23 degrees C versus 37 degrees C); (iii) washing of spermatozoa and (iv) a sperm metabolic enhancer, pentoxifylline. The duration of sperm motility was assessed by evaluating samples in each treatment every hour for 6 h and a sperm motility index (a value combining percentage sperm motility and rate of forward progression) calculated. Spermatozoa from the Ham's F10, PBS and PBS plus pentoxifylline treatments were also co-incubated with zona-intact, domestic cat eggs that were fixed and evaluated for spermatozoa bound to the zona pellucida, penetrating the outer and inner layers of the zona pellucida and within the perivitelline space. During the 6 h co-incubation, the sperm motility index in PBS with pentoxifylline was greater (P < 0.05) than in PBS alone which, in turn, was greater (P < 0.05) than in the other three test media. Washing the spermatozoa enhanced (P < 0.05) motility in both PBS and PBS plus pentoxifylline relative to unwashed samples, but there was no effect (P > 0.05) of holding temperature. Pentoxifylline supplementation enhanced (P < 0.05) the proportion of cat eggs with bound, but not penetrated, snow leopard spermatozoa in the inner layer of the zona pellucida, and there were no spermatozoa in the perivitelline space.(ABSTRACT TRUNCATED AT 250 WORDS) |
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0022-4251 |
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Document Type: eng |
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no |
| Call Number |
SLN @ rana @ 253 |
Serial |
828 |
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Roth, T.L.; Swanson, W.F.; Wildt, D.E.; Collins, D.; Burton, M.; Garell, D.M. |
| Title |
Snow leopard (Panthera uncia) spermatozoa are sensitive to alkaline pH, but motility in vitro is not influenced by protein or energy supplements |
Type |
Miscellaneous |
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1996 |
Publication |
Journal of Andrology |
Abbreviated Journal |
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| Volume |
17 |
Issue |
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Pages |
558-566 |
| Keywords |
Felid,comparative biology,sperm culture medium,sperm function,capacitation,sodium bicarbonate. |
| Abstract |
To better understand the biology of snow leopard spermatozoa and to facilitate developing assisted reproduction, a series of studies was conducted to: 1) identify the component(s) of complex culture media responsible for the detrimental effect on sperm survival in vitro, 2) optimize medium for supporting sperm viability, and 3) evaluate sperm capacitation in vitro. Constituents of complex media were added systematically to phosphate-buffered saline (PBS) to isolate the factor(s) influencing snow leopard sperm motility in vitro. Sperm capacitation was also assessed following incubation in PBS with bovine serum albumin (BSA), fetal calf serum (FCS), or heparin. For maintaining sperm motility, there was no benefit (P ? 0.05) to supplementing PBS with low (5%) or high (20%) concentrations of snow leopard serum (SLS) versus FCS or BSA. Likewise, adding supplemental energy substrates (pyruvate, glucose, lactate, or glutamine) did not enhance or hinder (P ? 0.05) sperm motility. However, motility rapidly decreased (P < 0.05) with the addition of NaHCO3 to PBS or Ham's F10 nutrient mixture. Surprisingly, Ham's F10 with no buffering component or with both NaHCO3 and N-Z-hydroxyethylpiperazine-N'-2- ethanesulfonic acid (HEPES) maintained sperm motility at levels similar (P ? 0.05) to PBS. Although sperm motility in all treatments decreased with time, there was a strong inverse relationship (P < 0.01; r = 0.90) between motility and sample pH at 6 hours. Spermatozoa incubated in PBS containing FCS, BSA, or heparin did not undergo the acrosome reaction when exposed to calcium ionophore. In summary, alkaline pH has a profound detrimental effect on snow leopard sperm motility, and capacitation does not occur under conditions that normally promote this event in other felid species. These results clearly demonstrate a high degree of interspecific variation among felids in fundamental sperm function, and they provide evidence for the necessity of basic research when developing assisted reproduction in little-studied nondomestic species. |
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no |
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SLN @ rana @ 897 |
Serial |
831 |
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| Author |
Schaffer, E.; Wiesner, H.; Von Hegel, G. |
| Title |
Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) |
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Journal Article |
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1988 |
Publication |
Tierarztl Prax |
Abbreviated Journal |
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| Volume |
16 |
Issue |
1 |
Pages |
87-91 |
| Keywords |
Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german |
| Abstract |
In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin. |
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0303-6286 |
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Document Type: German |
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no |
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SLN @ rana @ 112 |
Serial |
851 |
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