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Author |
Trepanier, L.A.; Cribb, A.E.; Spielberg, S.P.; Ray, K. |
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Title |
Deficiency of cytosolic arylamine N-acetylation in the domestic cat and wild felids caused by the presence of a single NAT1-like gene |
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Journal Article |
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1998 |
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Pharmacogenetics |
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8 |
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2 |
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169-179 |
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Keywords |
Acetylation; Amino; Acid; Sequence; Animal; Arylamine; N-Acetyltransferase; metabolism; Base; Blotting; Southern; Carnivora; genetics; Cats; Cytosol; enzymology; Dna; Human; Isoenzymes; Liver; Molecular; Data; Polymerase; Chain; Reaction; Rabbits; Homology; Nucleic Acid; Substrate; Specificity; Support; U.S.Gov't; P.H.S.; browse; nucleic; us; government; 130 |
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The purpose of this study was to determine the molecular basis for a relative deficiency in the cat of cytosolic arylamine N- acetyltransferase (NAT), an enzyme family that is important in the metabolism of xenobiotics and that normally consists of at least two related enzymes, NAT1 and NAT2. N-acetyltransferase in feline liver showed high affinity (mean Km = 2.1 microM) for p-aminobenzoic acid, an NAT1 selective substrate in humans and rabbits, but showed a very poor affinity (mean Km > 10 mM) for sulfamethazine, an NAT2 selective substrate in humans and rabbits. Immunoreactive N-acetyltransferase was detected in feline liver, bladder and colon using an NAT1-specific antipeptide antibody, but was not detected in any tissues using an NAT2- specific antibody. Southern blot analysis of genomic DNA demonstrated a single band in domestic cats using each of six restriction digests; single bands were also found on Southern blot analysis of six wild felids. The deduced amino acid sequence of the central portion of feline N-acetyltransferase, obtained by polymerase chain reaction amplification in both domestic cats and seven wild felids (lion, tiger, lynx, snow leopard, bobcat, Asian leopard cat and cheetah), contained three residues, Phe125, Arg127, and Tyr129, which determine NAT1-like substrate specificity in humans. These results support the conclusion that cytosolic arylamine N-acetylation activity is low in the cat because of the presence of a single N-acetyltransferase that has substrate specificity, immunogenicity and sequence characteristics similar to human NAT1, and that the unusual presence of only a single N- acetyltransferase gene appears to be a family wide trait shared by other felids. |
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0960-314x |
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Document Type: eng |
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SLN @ rana @ 345 |
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968 |
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Author |
Trivedi, P. |
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Title |
Project Snow Leopard: Participatory conservation model for the Indian Himalaya |
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Magazine Article |
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2009 |
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Mountain Forum Bulletin |
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Ix |
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2 |
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52-54 |
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assessment; biodiversity; biodiversity assessment; conservation; global; Himalaya; Icimod; indian; links; mountain; network; participatory; project; Project-snow-leopard; project snow leopard; projects; research; resource; snow-leopard; snow leopard; Support |
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Mountain Forum |
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1815-2139 |
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More details at: www.conservation.in or www.ncf-india.org and www.wii.gov.in Newsletter published biannually by Mountain Forum: www.mtnforum.org. Editorial Team: Marianne Heredge, Ujol Sherchan, Frans Neuman,
Laura Keenan, Sunita Chaudhary, Suman Jaiswal. This newlstter edition is a joint product of the Mountain Forum, GMBA and MRI with support from ICIMOD, and brings together contributions from the three networks and partners. It also has a section on links to interesting organisations, resources and projects on Mountain Biodiversity. Published by the Mountain Forum Secretariat in collaboration with the respective Nodes in
Africa, Asia-Pacific, Europe, Latin America and North America and with the assistance of the Mountain Research Initiative (MRI) and the Global Mountain Biodiversity Assessment (GMBA). |
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SLN @ rana @ 1054 |
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969 |
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Author |
Turner, L. |
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Title |
Oklahoma City Zoo-Twenty Nine Snow Leopards |
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Journal Article |
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1980 |
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Int.Ped Book of Snow Leopards |
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2 |
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96-111 |
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Keywords |
zoos; captivity; husbandry; zoo; breeding; housing; browse; 3690 |
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Discusses breeding, housing, aquisition, history |
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SLN @ rana @ 66 |
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974 |
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Tursun, H.; Wenhu, Y.; Meng, X.H. |
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Title |
Great Exploitation of the West and the Basic Thoughts of the Great Development Strategy of Xinjiang |
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2000 |
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Arid Land Geography |
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23 |
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3 |
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193-198 |
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5410 |
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In Chinese. |
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SLN @ rana @ 525 |
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975 |
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Author |
ud Din, J. |
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Title |
Assessing the Status of Snow Leopard in Torkhow Valley, District Chitral, Pakistan: Final Technical Report |
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Report |
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2008 |
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1-16 |
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Keywords |
status; snow; snow leopard; snow-leopard; leopard; valley; chitral; Pakistan; Report; study; prey; Base; conflict; threats; threat; wildlife; sign; transect; surveys; survey; Slims; Data; number; snow leopards; snow-leopards; leopards; Animals; Animal; population; livestock; livestock depredation; livestock-depredation; depredation; area; Case; ungulates; ungulate; Himalayan; himalayan ibex; ibex; rut; using; prey species; prey-species; species; marmot; game; birds; carnivores; carnivore; wolf; wolves; jackal; fox; survival; retaliatory; retaliatory killing; retaliatory-killing; killing; poisoning; poaching; loss; habitat; habitat degradation; habitat-degradation; degradation; grazing; collection; awareness; Gis; map; staff; field; training; conservation; community; distribution; resource; project; network; program |
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This study was aimed at assessing the status of Snow leopard, its major prey base, and the extent of human-Snow leopard conflict and major threats to the wildlife in north Chitral (Torkhow valley) Pakistan. Snow leopard occurrence was conformed through sign transect surveys i.e. SLIMS. Based on the data collected the number of Snow leopards in this survey block (1022 Kmý) is estimated to be 2-3 animals. Comparing this estimate with the available data from other parts of the district the population of snow leopard in Chitral district was count to be 36 animals. Livestock depredation reports collected from the area reflect the existence of human-snow leopard conflict and 138 cases were recorded affecting 102 families (in a period of eight years, 2001-2008). Ungulates (Himalayan Ibex) rut season surveys were conducted in coordination with NWFP Wildlife department. A total of 429 animals were counted using direct count (point method) surveys. Other snow leopard prey species recorded include marmot, hare, and game birds. Signs of other carnivores i.e. wolf, jackal, and fox were also noticed. Major threats to the survival of wildlife especially snow leopard reckoned include retaliatory killing (Shooting, Poisoning), poaching, loss of natural prey, habitat degradation (over grazing, fodder and fuel wood collection), lack of awareness, and over population. GIS map of the study area was developed highlighting the area searched for Snow leopard and its prey species. Capacity of the Wildlife Department staff was built in conducting SLIMS and ungulate surveys through class room and on field training. Awareness regarding the importance of wildlife conservation was highlighted to the students, teachers and general community through lectures and distribution of resource materials developed by WWF-Pakistan. |
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Project funded by Snow Leopard Network's Snow Leopard Conservation Grant Program. |
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Call Number |
SLN @ rana @ 1065 |
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978 |
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Author |
Usgs; International Snow Leopard Trust |
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Snow Leopard Habitat Map |
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Map |
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1995 |
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map; habitat; 4860; snow; snow leopard; snow-leopard; leopard; range; Pakistan; resource; Division; trust; International; symposium; Jackson |
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ISLT and World Wide Fund for Nature - Pakistan |
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Pakistan |
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Snow leopard range map published in: Proceedings of the Eighth International Snow Leopard Symposium. Held in Islamabad, Pakistan 12-16 November 1995. Editors of proceedings: Rodney Jackson and Ashiq Ahmad. Map authors U.S.G.S. Biological Resources Division and Snow Leopard Trust. Page 9. |
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SLN @ rana @ 471 |
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979 |
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Vashetko, E.; Esipov A.; Bykova, E.; Kreuzberg, E. |
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Snow Leopard Bibliography. Central Asia (Abstracts) |
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Manuscript |
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2005 |
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analysis; asia; bibliography; central; Central Asia; conservation; ecology; International; International-Snow-Leopard-Trust; international snow leopard trust; Islt; leopard; project; region; Russian; snow; snow-leopard; snow leopard; species; trust; work |
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Bibliography of the Snow Leopard included publications on the studying various questions of ecology and conservation of the Snow Leopard in Central Asia (305) for the period 1873 to 2004. The most important works on this species in the region, as well as results of the analysis of timing of publications was described. |
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English version. Also available in Russian in the SLN bibliography. Project supported by International Snow Leopard Trust (ISLT), was carried out in 2004-2005. |
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SLN @ rana @ 1061 |
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983 |
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Author |
Velte, F. |
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Snow leopards at the Seneca Zoological Park, Rochester |
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1982 |
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International Pedigree Book of Snow Leopards, Vol. 3 |
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3 |
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55-58 |
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captive; International; park; pedigree; snow-leopard; snow-leopards; snow leopard; snow leopards; zoo; zoological |
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Helsinki Zoo |
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Helsinki |
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Blomqvist, L. |
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SLN @ rana @ 1040 |
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984 |
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Vogt, P. |
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Title |
New enclosures for snow leopards (Uncia uncia) at Krefeld Zoo |
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1982 |
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International Pedigree Book of Snow Leopards, Vol. 3 |
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3 |
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67-70 |
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captive; enclosures; International; pedigree; snow-leopard; snow-leopards; snow leopard; snow leopards; uncia; Uncia-uncia; Uncia uncia; zoo |
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Helsinki Zoo |
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Helsinki |
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Blomqvist, L. |
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SLN @ rana @ 1041 |
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988 |
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Volozheninov, N.N. |
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Rare and vanishing mammals and birds in S Uzbekistan. Ecology and protection of the rare and vanishing vertebrates in Uzbekistan, Tashkent |
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1985 |
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Uzbekistan; Russia; Soviet-Union; Ussr; browse; soviet union; soviet; union; 2610; Russian |
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In Russian |
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SLN @ rana @ 90 |
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991 |
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