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Author Schaffer, E.; Wiesner, H.; Von Hegel, G. url 
  Title Multiple ocular coloboma (MOC) with persistent pupillary membrane in the snow leopard (Panthera uncia) Type Journal Article
  Year 1988 Publication Tierarztl Prax Abbreviated Journal  
  Volume 16 Issue 1 Pages 87-91  
  Keywords Animal; Carnivora; Case; Report; Coloboma; etiology; pathology; veterinary; Comparative; study; Eyelids; abnormalities; Male; Optic; Nerve; Syndrome; browse; 270; german  
  Abstract (up) In a litter of three snow leopards, bilateral colobomata of the upper temporal eyelids, bilateral persistent pupillary membranes and a unilateral coloboma of the optic nerve entrance are described as “Multiple Ocular Colobomata” (MOC). The causal pathogenesis of each of the colobomata is discussed comparatively. The colobomata of the eyelids, essential feature of the MOC syndrome in snow leopards, are most probably not of hereditary, but rather of intrauterine infectious viral origin.  
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  ISSN 0303-6286 ISBN Medium  
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  Notes Document Type: German Approved no  
  Call Number SLN @ rana @ 112 Serial 851  
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Author Machado, C.; Brown, P.; Turner, R. url 
  Title Dental crown restorations on a snow leopard Type Journal Article
  Year 1984 Publication Journal Of Zoo Animal Medicine Abbreviated Journal  
  Volume 15 Issue 4 Pages 146-150  
  Keywords dentistry; veterinary; medical; medicine; zoo; zoos; captivity; browse; 1560  
  Abstract (up) In the spring of 1983 the San Francisco Zoo received a female snow leopard (Panthera uncia) as part of an exotic animal exchange program with the People's Republic of China. Upon examination, it was found that this nine-yea old, seventy-five pound, wild-trapped animal had sustained considerable dental injuries, including fractures of all maxillary and mandibular anterior teeth. The purpose of this paper is to describe the dental procedures undertaken to restore the physiological function of all four canines.  
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  Notes Addresses:MACHADO C, SAN FRANCISCO ZOO,SAN FRANCISCO,CA Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English Approved no  
  Call Number SLN @ rana @ 74 Serial 633  
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Author Sosnovskiy I.P. url 
  Title Backstage of the Zoo Type Miscellaneous
  Year 1981 Publication Abbreviated Journal  
  Volume Issue Pages 52-79  
  Keywords Russia; Moscow Zoo; zootechnik service; veterinary service; reptiles; birds; mammals; carnivores; snow leopard.; 8300; Russian  
  Abstract (up) It describes the Moscow Zoo services organization in a popular form; examples from every day work of the technical staff and zoo technical and veterinary service, animals' behaviour outside the cages are given.  
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  Notes Full text available in RussianJournal Title: Live museums. Approved no  
  Call Number SLN @ rana @ 808 Serial 916  
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Author Gosselin, S.J.; Loudy, D.L.; Tarr, M.J.; Balistreri, W.F.; Setchell, K.D.; Johnston, J.O.; Kramer, L.W.; Dresser, B.L. url 
  Title Veno-occlusive disease of the liver in captive cheetah Type Journal Article
  Year 1988 Publication Vet Pathol Abbreviated Journal  
  Volume 25 Issue 1 Pages 48-57  
  Keywords Animal; Feed; analysis; Carnivora; Cheetahs; Female; Hepatic; Veno; Occlusive; Disease; pathology; veterinary; Histocytochemistry; Liver; ultrastructure; Male; Microscopy; Electron; Support; Non-U.S.Gov't; Vitamin A; browse; non; us; gov't; government; 280  
  Abstract (up) Liver tissues from 126 captive cheetah were evaluated by light microscopy and histochemistry; eight animals were evaluated by electron microscopy. The main hepatic lesion, a vascular lesion resembling veno- occlusive disease (VOD) of the liver and characterized by subendothelial fibrosis and proliferation of smooth muscle-like cells in the central veins, was seen in 60% of the sexually mature cheetah. Although this hepatic vascular lesion was seen in cheetah as young as 1 year of age, the most severe lesions, usually associated with liver failure, were found in cheetah between the ages of 6 and 11. There was no sex predisposition, and in approximately 40% of the VOD cases, liver disease was not suspected clinically or at necropsy. VOD was found in other felidae, especially in the snow leopard. High levels of vitamin A in livers, as well as in diets of the cheetah, could be a contributing factor in the development of VOD in some groups of cheetah.  
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  ISSN 0300-9858 ISBN Medium  
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  Notes Document Type: Eng Approved no  
  Call Number SLN @ rana @ 127 Serial 339  
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Author Munson, L.; Worley, M.B. url 
  Title Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks Type Journal Article
  Year 1991 Publication Vet Pathol Abbreviated Journal  
  Volume 28 Issue 1 Pages 37-45  
  Keywords Cirrhosis; epidemiology; Hemosiderosis; Hepadnaviridae; Hepatic; Hepatitis; pathology; Veno-Occlusive; veterinary; zoo  
  Abstract (up) Livers from 54 snow leopards, 4 days to 23 years old, that had died in 23 US zoos, were evaluated histopathologically to determine if the hepatic fibrosis, which has been noted to be prevalent in this species, was due to chronic active hepatitis from hepadnaviral infection, Ito cell proliferation, or hemosiderosis. Forty-two of 54 snow leopards had subintimal vascular fibrosis with partial or total occlusion of central and sublobular veins (veno-occlusive disease) of unknown origin. All 21 leopards older than 5 years were affected. Four leopards had chronic active hepatitis, and 12 leopards had cholangiohepatitis; but these lesions were not connected anatomically to central and sublobular venous fibrosis. Hepatocellular and Kupffer cell siderosis and Ito cell proliferation were prevalent and often coexisted with perisinusoidal, central, and sublobular venous fibrosis; but fibrosis was present in leopards without siderosis or Ito cell proliferation. The pattern and prevalence of veno-occlusive disease in these leopards was similar to that reported in captive cheetah (Acinonyx jubatus), suggesting that a common extrinsic factor may cause the majority of hepatic disease in these large felid animals in captivity.  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 173 Serial 706  
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Author Kazensky, C.A.; Munson, L.; Seal, U.S.   
  Title The effects of melengestrol acetate on the ovaries of captive wild felids Type Journal Article
  Year 1998 Publication Journal-of-Zoo-and-Wildlife-Medicine Abbreviated Journal  
  Volume 29 Issue 1 Pages 1-5  
  Keywords Mga; zoo; felids; contraception; Melengestrol-acetate; ovaries; snow-leopard; Panthera-uncia; snow leopard; browse; uncia; panthera; melengestrol; acetate; 1260; effects; study; ovarian; Ovary; captive; wild; wild felid; Wild-Felid; species; Follicle; Cats; cat; recent; Ovulation; doses; Dose; action; Progestin; Disease; veterinary  
  Abstract (up) Melengestrol acetate (MGA) is the most widely used contraceptive in zoo felids, but the mechanism of contraception and the pathologic effects have not been investigated. For this study, the effects of MGA on folliculogenesis were assessed, and the association of MGA with ovarian lesions was evaluated. Comparisons were made among the histopathologic findings in the ovaries from 88 captive wild felids (representing 15 species) divided into three groups: 37 currently contracepted with MGA, eight previously exposed to MGA, and 43 never contracepted. Ninety-one percent of the felids evaluated had tertiary follicles, and no differences were noted between contracepted and uncontracepted cats. Some MGA-contracepted cats also had corpora lutea indicating recent ovulation. These results indicate that folliculogenesis is not suppressed by current doses of MGA and ovulation occurred in some cats. Therefore, the contraceptive actions of MGA do not occur by suppressing folliculogenesis, and MGA-contracepted felids likely have endogenous estrogens that may confound progestin effects on the uterus. Cystic rete ovarii was the most common pathologic finding, but they were not more prevalent in MGA-contracepted cats. These findings indicate that MGA is not associated with ovarian disease, including ovarian cancer, in contrast to the uterine lesions noted in MGA-treated cats.  
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  Notes Document Type: English. Affiliation: Taylor Veterinary Hospital, Turlock , California 95382, USA Approved no  
  Call Number SLN @ rana @ 348 Serial 527  
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Author Pollock, R.V.; Carmichael, L.E. url 
  Title Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus Type Journal Article
  Year 1983 Publication Am J Vet Res Abbreviated Journal  
  Volume 44 Issue 2 Pages 169-175  
  Keywords Animal; Antibodies; Viral; biosynthesis; Dog; Diseases; microbiology; prevention; control; Dogs; Dose; Response; Relationship; Immunologic; Parvoviridae; immunology; Parvovirus; Feline; growth; development; Support; Non-U.S.Gov't; Vaccines; Attenuated; Virus; veterinary; Replication; browse; 350  
  Abstract (up) Modified live feline panleukopenia virus (FPLV) vaccine protected dogs against canine parvovirus (CPV) infection. However, unlike the long- lived (greater than or equal to 20-month) immunity engendered by CPV infection, the response of dogs to living FPLV was variable. Doses of FPLV (snow leopard strain) in excess of 10(5.7) TCID50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. The duration of immunity, as measured by the persistence of hemagglutination-inhibiting antibody, was related to the magnitude of the initial response to vaccination; dogs with vigorous initial responses resisted oronasal CPV challenge exposure 6 months after vaccination, and hemagglutination-inhibiting antibodies persisted in such dogs for greater than 1 year. Limited replication of FPLV in dogs was demonstrated, but unlike CPV, the feline virus did not spread to contact dogs or cats. Adverse reactions were not associated with living FPLV vaccination, and FPLV did not interfere with simultaneous response to attenuated canine distemper virus.  
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  ISSN 0002-9645 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 69 Serial 784  
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Author Wildt, D.; Pukazhenthi, B.; Brown, J.; Monfort, S.; Howard, J.; Roth, T. url 
  Title Spermatology for understanding, managing and conserving rare species Type Journal Article
  Year 1995 Publication Reproduction Fertility and Development Abbreviated Journal  
  Volume 7 Issue 4 Pages 811-824  
  Keywords Assisted-Reproduction; Cryopreservation; reproduction; zoo; medical; veterinary; spermatology; genetics; browse; assisted; 1380  
  Abstract (up) Most conventional spermatology research involves common mammalian species including livestock, laboratory animals and humans. Yet, there are more than 4500 mammalian species inhabiting the planet for which little is known about basic reproductive biology, including sperm characteristics and function. This information is important, not just as adjunct knowledge, but because the majority of these species are threatened with extinction, largely due to human-induced pressures. The field of conservation is changing rapidly, and global cooperation is emerging among a variety of wildlife enthusiasts, ranging from management authorities of nature reserves to curators of rare zoological collections. Conservation progress depends on systematic, multidisciplinary research first to answer basic questions, with new data then applied to endangered species management plans. The reproductive physiologist is a crucial component of this scheme. Reproduction is the essence of species survival, and enormous effort needs to be directed at these 'untraditional' research species, subspecies and populations. Spermatology research combined with simultaneous efforts in endocrinology, embryology and cryopreservation (among others) can lead to the successful application of assisted reproduction. Examples from this laboratory include an array of wild felid species and a rare cervid and mustelid. Obstacles to success are formidable, including unique species-specificities, diminished genetic diversity and a general lack of resources. Nonetheless, the field offers tremendous opportunities for generating unique knowledge of comparative interest and with conservation utility.  
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  Notes Document Type: English Approved no  
  Call Number SLN @ rana @ 278 Serial 1024  
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Author Lanier, D.L.; Dewsbury, D.A. url 
  Title A quantitative study of copulatory behaviour of large Felidae Type Journal Article
  Year 1976 Publication Behavioural-Processes Abbreviated Journal  
  Volume 1 Issue 4 Pages 327-333  
  Keywords behavior; breeding; mating; copulation; veterinary; zoo; zoos; medical; reproduction; browse; 1590  
  Abstract (up) Observed a total of 109 copulations in 6 male-female pairs from 4 species of large Felidae. The mean intromission durations were 3.0 sec for Asian leopards (Panthera pardus), 3.3 sec for African leopards (P. pardus), 12.9 sec for snow leopards (Uncia uncia), 2.3 sec for spotted jaguars (P. onca), 3.3 sec for black jaguars (P. onca), and 12.4 sec for Siberian tigers (P. tigris). Behavioral patterns were qualitatively similar across species; all displayed a copulatory pattern with no lock, no intravaginal thrusting, ejaculation on a single insertion, and multiple ejaculations. Whereas domestic cats are reported to assume a neck grip and to tread prior to insertion, these larger Felidae generally did so after intromission had been achieved. After copulation, females of some pairs swiped at the male and displayed a rolling after-reaction. (18 ref) (PsycINFO Database Record (c) 2000 APA, all rights reserved)(unassigned)  
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  Notes Netherlands: Elsevier Science Publishers BV. Approved no  
  Call Number SLN @ rana @ 32 Serial 610  
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Author Roth, T.L.; Armstrong, D.L.; Barrie, M.T.; Wildt, D.E. url 
  Title Seasonal effects on ovarian responsiveness to exogenous gonadotrophins and successful artificial insemination in the snow leopard (Uncia uncia) Type Journal Article
  Year 1997 Publication Reprod Fertil Dev Abbreviated Journal  
  Volume 9 Issue 3 Pages 285-295  
  Keywords Animal; Carnivora; anatomy; histology; Blood; physiology; Estradiol; Female; Gonadotropins; administration; dosage; pharmacology; Chorionic; Equine; Human; Insemination; artificial; methods; veterinary; Laparoscopy; Male; Oocytes; cytology; Ovary; drug; effects; Ovulation; Induction; Pregnancy; Progesterone; Seasons; Support; Non-U.S.Gov't; browse; non; us; gov't; government; 400  
  Abstract (up) Ovaries of the seasonally-breeding snow leopard (Uncia uncia) were examined to determine whether they were responsive to exogenous gonadotrophins throughout the year. The potential of laparoscopic artificial insemination (AI) also was assessed for producing offspring. During the non-breeding, pre-breeding, breeding and post-breeding seasons, females (n = 20) were treated with a standardized, dual- hormone regimen given intramuscularly (600 I.U. of equine chorionic gonadotrophin followed 80-84 h later with 300 I.U. of human chorionic gonadotrophin (hCG)). Laparoscopy was performed 45-50 h after administration of hCG, and all ovarian structures were described. Females with fresh corpora lutea (CL) were inseminated, and anovulatory females were subjected to follicular aspiration to examine oocyte quality. Snow leopards responded to exogenous gonadotrophins throughout the year. Mean number of total ovarian structures (distinct follicles mature in appearance plus CL) did not differ (P > or = 0.05) with season, but the proportion of CL: total ovarian structures was greater (P < 0.01) for the breeding season compared with all other seasons. The proportion of females ovulating was greater (P < 0.05) during the breeding and post-breeding seasons than during the pre-breeding and non- breeding seasons respectively. No Grade-1 quality oocytes were recovered from follicles of anovulatory females. Serum concentrations of oestradiol-17 beta appeared elevated in all females, and neither oestradiol-17 beta concentrations nor progesterone concentrations differed (P > or = 0.05) among seasons. Of 15 females artificially inseminated, the only one that was inseminated in the non-breeding season became pregnant and delivered a single cub. This is the first successful pregnancy resulting from AI in this endangered species.  
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  ISSN 1031-3613 ISBN Medium  
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  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 325 Serial 830  
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