Abstract: A vertebrate fauna inventory in the Hissar nature reserve showed that various natural zones here are certainly inhabited by 45 species: amphibians one species; reptiles 12; mammals 32. Reptiles such as Alai snake-eyed skink and Central Asian viper and mammal species such as wolf, fox, brown bear, weasel, grey hamster can be found in all natural zones here up to 4,000 m above sea level. Snow leopard, Turkestan lynx, and long-tailed marmot can be found in the juniperous forests and higher elevations.