Abstract: It provides general information about the Hissar nature reserve (Uzbekistan), its physico-geographical features and description of flora and fauna. The following predator species inhabit the nature reserve: wolf, fox, Tien Shan brown bear (four five animals per 100 sq. km), ermine, weasel, stone marten, otter, badger, lynx (two animals per 100 sq. km) and snow leopard (about 10 animals). Wild boar and ibex are common species for the area (22 25 animals per 100 sq. km).