Abstract: Due to development of new lands and increased anthropogenic pressure animals are displaced from their habitats. Intense poaching caused dying away a number of animals such as Turan tiger, moral, and kulan in Uzbekistan at the end of 19th beginning of 20th century. The endangered species are marchor, cheetah, lynx, snow leopard, caracal, and cobra. Species put on the verge of a total extermination are included in the national Red Data Book (22 mammal species, 31 bird species, five reptile and five fish species). The introduction of some species such as raccoon, European fallow deer, nylghau, and chinchilla was unsuccessful.