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Author (up) Thorel, M.F.; Karoui, C.; Varnerot, A.; Fleury, C.; Vincent, V. url  openurl
  Title Isolation of Mycobacterium bovis from baboons, leopards and a sea-lion Type Journal Article
  Year 1998 Publication Vet Res Abbreviated Journal  
  Volume 29 Issue 2 Pages 207-212  
  Keywords Animal; Animals; zoo; Carnivora; microbiology; Case; Report; Cattle; Dna; Fingerprinting; Transposable; Elements; Disease; Outbreaks; veterinary; France; Genome; Bacterial; Germany; Male; Monkey; Diseases; diagnosis; epidemiology; Mycobacterium; Infections; bovis; classification; isolation; purification; Papio; Seals; browse; 440  
  Abstract This study reports on two series of cases of Mycobacterium bovis infection in zoo animals. The first was in a captive population of baboons (Papio hamadryas) and the second in a mixed group of wild mammals, including four leopards (Panthera uncia and Panthera pardus) and a sea-lion (Otaria byrona). The isolation and identification of strains of M. bovis confirmed the presence of M. bovis infections in both zoos. The epidemiological study using genetic markers such as the IS6110-based DNA fingerprinting system made it possible to differentiate between M. bovis strains. The M. bovis strains isolated from baboons were shown to contain a single IS6110 copy, as usually do cattle isolates, whereas the M. bovis strains isolated from the other exotic animals presented multiple copies. This finding suggests that the origin of the contamination for the baboons in zoo A could be related to cattle. The origin of the contamination for the leopards and sea-lion in zoo B is more difficult to determine. In conclusion, the authors suggest some recommendations for avoiding outbreaks of tuberculosis infections in zoos.  
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  Series Volume Series Issue Edition  
  ISSN 0928-4249 ISBN Medium  
  Area Expedition Conference  
  Notes Document Type: eng Approved no  
  Call Number SLN @ rana @ 346 Serial 966  
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