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Jalanka, H.H. |
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Medetomidine-induced and ketamine-induced immobilization of snow leopards (Panthera uncia) doses, evaluation and reversal by atipamezole |
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1989 |
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Journal of Zoo and Wildlife Medicine |
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20 |
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2 |
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154-162 |
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immobilization; drugs; dossage; doses; medetomidine; ketamine; veterinary; medical; medicine; zoo; zoos; atipamezole; browse; 1500 |
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Addresses:JALANKA HH, HELSINKI ZOO,SF-00570 HELSINKI,FINLAND Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English |
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SLN @ rana @ 146 |
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484 |
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Kazensky, C.A.; Munson, L.; Seal, U.S. |
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Title |
The effects of melengestrol acetate on the ovaries of captive wild felids |
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Journal Article |
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1998 |
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Journal-of-Zoo-and-Wildlife-Medicine |
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29 |
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1 |
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1-5 |
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Mga; zoo; felids; contraception; Melengestrol-acetate; ovaries; snow-leopard; Panthera-uncia; snow leopard; browse; uncia; panthera; melengestrol; acetate; 1260; effects; study; ovarian; Ovary; captive; wild; wild felid; Wild-Felid; species; Follicle; Cats; cat; recent; Ovulation; doses; Dose; action; Progestin; Disease; veterinary |
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Melengestrol acetate (MGA) is the most widely used contraceptive in zoo felids, but the mechanism of contraception and the pathologic effects have not been investigated. For this study, the effects of MGA on folliculogenesis were assessed, and the association of MGA with ovarian lesions was evaluated. Comparisons were made among the histopathologic findings in the ovaries from 88 captive wild felids (representing 15 species) divided into three groups: 37 currently contracepted with MGA, eight previously exposed to MGA, and 43 never contracepted. Ninety-one percent of the felids evaluated had tertiary follicles, and no differences were noted between contracepted and uncontracepted cats. Some MGA-contracepted cats also had corpora lutea indicating recent ovulation. These results indicate that folliculogenesis is not suppressed by current doses of MGA and ovulation occurred in some cats. Therefore, the contraceptive actions of MGA do not occur by suppressing folliculogenesis, and MGA-contracepted felids likely have endogenous estrogens that may confound progestin effects on the uterus. Cystic rete ovarii was the most common pathologic finding, but they were not more prevalent in MGA-contracepted cats. These findings indicate that MGA is not associated with ovarian disease, including ovarian cancer, in contrast to the uterine lesions noted in MGA-treated cats. |
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Document Type: English. Affiliation: Taylor Veterinary Hospital, Turlock , California 95382, USA |
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SLN @ rana @ 348 |
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527 |
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Pollock, R.V.; Carmichael, L.E. |
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Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus |
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1983 |
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Am J Vet Res |
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44 |
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2 |
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169-175 |
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Animal; Antibodies; Viral; biosynthesis; Dog; Diseases; microbiology; prevention; control; Dogs; Dose; Response; Relationship; Immunologic; Parvoviridae; immunology; Parvovirus; Feline; growth; development; Support; Non-U.S.Gov't; Vaccines; Attenuated; Virus; veterinary; Replication; browse; 350 |
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Modified live feline panleukopenia virus (FPLV) vaccine protected dogs against canine parvovirus (CPV) infection. However, unlike the long- lived (greater than or equal to 20-month) immunity engendered by CPV infection, the response of dogs to living FPLV was variable. Doses of FPLV (snow leopard strain) in excess of 10(5.7) TCID50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. The duration of immunity, as measured by the persistence of hemagglutination-inhibiting antibody, was related to the magnitude of the initial response to vaccination; dogs with vigorous initial responses resisted oronasal CPV challenge exposure 6 months after vaccination, and hemagglutination-inhibiting antibodies persisted in such dogs for greater than 1 year. Limited replication of FPLV in dogs was demonstrated, but unlike CPV, the feline virus did not spread to contact dogs or cats. Adverse reactions were not associated with living FPLV vaccination, and FPLV did not interfere with simultaneous response to attenuated canine distemper virus. |
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0002-9645 |
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Document Type: eng |
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SLN @ rana @ 69 |
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784 |
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