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Jalanka, H.H. |
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Medetomidine-induced and ketamine-induced immobilization of snow leopards (Panthera uncia) doses, evaluation and reversal by atipamezole |
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1989 |
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Journal of Zoo and Wildlife Medicine |
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20 |
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2 |
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154-162 |
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immobilization; drugs; dossage; doses; medetomidine; ketamine; veterinary; medical; medicine; zoo; zoos; atipamezole; browse; 1500 |
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Addresses:JALANKA HH, HELSINKI ZOO,SF-00570 HELSINKI,FINLAND Publisher:AMER ASSOC Z00 VETERINARIANS, MEDIA Document Type: English |
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SLN @ rana @ 146 |
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484 |
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Kazensky, C.A.; Munson, L.; Seal, U.S. |
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Title |
The effects of melengestrol acetate on the ovaries of captive wild felids |
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Journal Article |
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1998 |
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Journal-of-Zoo-and-Wildlife-Medicine |
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29 |
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1 |
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1-5 |
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Mga; zoo; felids; contraception; Melengestrol-acetate; ovaries; snow-leopard; Panthera-uncia; snow leopard; browse; uncia; panthera; melengestrol; acetate; 1260; effects; study; ovarian; Ovary; captive; wild; wild felid; Wild-Felid; species; Follicle; Cats; cat; recent; Ovulation; doses; Dose; action; Progestin; Disease; veterinary |
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Abstract |
Melengestrol acetate (MGA) is the most widely used contraceptive in zoo felids, but the mechanism of contraception and the pathologic effects have not been investigated. For this study, the effects of MGA on folliculogenesis were assessed, and the association of MGA with ovarian lesions was evaluated. Comparisons were made among the histopathologic findings in the ovaries from 88 captive wild felids (representing 15 species) divided into three groups: 37 currently contracepted with MGA, eight previously exposed to MGA, and 43 never contracepted. Ninety-one percent of the felids evaluated had tertiary follicles, and no differences were noted between contracepted and uncontracepted cats. Some MGA-contracepted cats also had corpora lutea indicating recent ovulation. These results indicate that folliculogenesis is not suppressed by current doses of MGA and ovulation occurred in some cats. Therefore, the contraceptive actions of MGA do not occur by suppressing folliculogenesis, and MGA-contracepted felids likely have endogenous estrogens that may confound progestin effects on the uterus. Cystic rete ovarii was the most common pathologic finding, but they were not more prevalent in MGA-contracepted cats. These findings indicate that MGA is not associated with ovarian disease, including ovarian cancer, in contrast to the uterine lesions noted in MGA-treated cats. |
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Document Type: English. Affiliation: Taylor Veterinary Hospital, Turlock , California 95382, USA |
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SLN @ rana @ 348 |
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527 |
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